Phospholipase A2 and phospholipase C activities of platelets. Differential substrate specificity, Ca2+ requirement, pH dependence, and cellular localization (original ) (raw )Human platelet phospholipase A2 activity is responsive in vitro to pH and Ca2+ variations which parallel those occurring after platelet activation in vivo
Lee Limbird
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1988
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Properties and distribution of phosphatidylinositol-specific phospholipase C in human and horse platelets
Eduardo Lapetina
Biochimica et biophysica acta, 1983
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Localisation of phospholipase A2 and diglyceride lipase activities in human platelet intracellular membranes
Michel Lagarde
FEBS Letters, 1981
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Characterization of phosphoinositide-specific phospholipase C from human platelets
Veeraswamy Manne
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Degradation of phosphatidylinositol-4,5-bisphosphate is insensitive to Ca2+ mobilization in stimulated platelets
Md Motasim Billah
Biochemical and Biophysical Research Communications, 1982
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Organization and role of platelet membrane phospholipids as studied with phospholipases A2 from various venoms and phospholipases C from bacterial origin
Gerard Mauco
Toxicon, 1982
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1,2-Diacylglycerols do not potentiate the action of phospholipases A2 and C in human platelets
Eduardo Lapetina
Biochemical and Biophysical Research Communications, 1984
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The Relationship between Phospholipases A 2 and C in Signal Transduction
Eduardo Lapetina
Ann N Y Acad Sci, 1989
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Secretory phospholipase A2 is not required for arachidonic acid liberation during platelet activation
Bernardo Vargaftig
European Journal of Biochemistry, 1993
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Different susceptibilities of platelet phospholipids to various phospholipases and modifications induced by thrombin. Possible evidence of rearrangement of lipid domains
W. Tsai
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1987
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Estimation of the phospholipid distribution in the human platelet plasma membrane based on the effect of phospholipase A2 from Naja nigricollis
Young-Ji Shiao
Biochimica et Biophysica Acta (BBA) - Biomembranes, 1986
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No direct correlation between Ca2+ mobilization and dissociation of Gi during platelet phospholipase A2 activation
Eduardo Lapetina
Biochemical and Biophysical Research Communications, 1988
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Human platelet activation by bacterial phospholipase C: Mechanism of inhibition by flurazepam
Khursheed Anwer
Thrombosis Research, 1988
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Biochimica et biophysica acta, 1994
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Phosphorylation of the 47 KDa protein in gamma-thrombin-stimulated human platelets does not activate phospholipase A2: Evidence against lipocortin
Eduardo Lapetina
Biochemical and Biophysical Research Communications, 1986
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Restoration of Responsiveness of Phospholipase Cγ2-Deficient Platelets by Enforced Expression of Phospholipase Cγ1
Peter Newman
PLOS ONE, 2015
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Hypersensitivity of phospholipase C in platelets of spontaneously hypertensive rats
Adnane Remmal
Hypertension, 1987
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Carrageenan-induced activation of human platelets is dependent on the phospholipase C Pathway
Jacques Randon
British Journal of Haematology, 1993
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Studies on enzymes related to diacylglycerol production in activated plateletsI. phosphatidylinositol-specific phospholipasec: Further characterization using a simple method for determination of activity
Gerard Mauco
Biochimica Et Biophysica Acta Lipids and Lipid Metabolism, 1984
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Identification of the Phosphorylation Sites of Cytosolic Phospholipase A2 in Agonist-stimulated Human Platelets and HeLa Cells
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Journal of Biological Chemistry, 1998
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Christopher Stubbs
Lipids, 1992
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Thrombosis Research, 1993
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Regulation of Plasma Membrane Ca2+-ATPase by Small GTPases and Phosphoinositides in Human Platelets
Juan Rosado
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Targeting of Porcine Pancreatic Phospholipase A2 to Human Platelets. Introduction of an RGD Sequence and Acyl-Group by Chemical Modification
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European Journal of Biochemistry, 1996
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A Critical Role for Phospholipase C 2 in IIb 3-mediated Platelet Spreading
David Vaux
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Specific binding of [alpha-32P]GTP to cytosolic and membrane-bound proteins of human platelets correlates with the activation of phospholipase C
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Proceedings of the National Academy of Sciences, 1987
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Phospholipid-platelet activating factor interactions probed by monolayers, pyrene fluorescence and phospholipase A2
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Correlation between changes in Na+/H+-exchange and cytoplasmic Ca concentration during platelet activation
deependra soni
Bulletin of Experimental Biology and Medicine, 1988
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A role for protein phosphorylation in modulating Ca2+ elevation in rabbit platelets treated with thapsigargin
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