PCOS Guideline Management of Polycystic Ovary Syndrome in India (original) (raw)
Related papers
Polycystic Ovary Syndrome ( Pcos ) and Related Diseases
2018
Humira Jeelani 1 , Mohd Ashraf Ganie 2 , Shajrul Amin 1 , Iram Ashaq Kawa 1 , Qudsia Fatima 1 , Zainab Drabu 3 , Fouzia Rashid 1 * 1 Department of Biochemistry/Clinical Biochemistry, University of Kashmir, Srinagar, Jammu and Kashmir, INDIA 2 Professor, Department of Endocrinology, Sher-I-Kashmir Institute of Medical Sciences, Soura, Srinagar, Jammu and Kashmir, INDIA 3 Consultant, Gynecology & Obstetrics, Govt. Lal Ded Hospital, Srinagar, Jammu and Kashmir, INDIA REVIEW _______________________________
Polycystic Ovary Syndrome (PCOS)
The endocrine disorders among females are of various types but the most common one is the polycystic ovary syndrome (PCOS) which is basically an inherited disorder and can be received from either parent. The chances of occurrence of this disorder vary from 5-10% among the females of age group of 12-45 resulting in female sub-fertility. This endocrine disorder can be identified by anovulation which is diagnosed by irregular menstruation, amenorrhea, polycystic ovaries, ovulation-related infertility, excessive secretion of androgenic hormones that cause hirsutism and acne. High cholesterol level, type 2 diabetes, insulin resistance are other known symptoms. All these symptoms vary among different individuals. The disorder is known by a number of other names like polycystic ovary disease, functional ovarian hyperandrogenism, ovarian hyperthecosis and Stein-Leventhal syndrome. A polycystic ovary has abnormal number of eggs that can be viewed near its surface resembling cysts.
2004
Since the 1990 NIH-sponsored conference on polycystic ovary syndrome (PCOS), it has become appreciated that the syndrome encompasses a broader spectrum of signs and symptoms of ovarian dysfunction than those de®ned by the original diagnostic criteria. The 2003 Rotterdam consensus workshop concluded that PCOS is a syndrome of ovarian dysfunction along with the cardinal features hyperandrogenism and polycystic ovary (PCO) morphology. PCOS remains a syndrome and, as such, no single diagnostic criterion (such as hyperandrogenism or PCO) is suf®cient for clinical diagnosis. Its clinical manifestations may include: menstrual irregularities, signs of androgen excess, and obesity. Insulin resistance and elevated serum LH levels are also common features in PCOS. PCOS is associated with an increased risk of type 2 diabetes and cardiovascular events.
Polycystic Ovary Syndrome (PCOS): A Concerning Hormonal Condition and its Bodily Impact on Women
BioScientific Review
Polycystic Ovary Syndrome (PCOS) is a prevalent hormonal disorder that have severe health consequences for women. It arises in the early puberty stage and affects a large percentage of the world’s population. While the exact cause is unknown, it’s known to cause hyperandrogenism, insulin resistance, menstrual irregularities, and ovulatory dysfunction, all of which can lead to infertility and endometrial cancer. Long-term cardiometabolic risks and comorbidities are seen in both slim and obese PCOS patients. Given these serious implications, it’scritical to fully comprehend the pathophysiological relationships that underpin PCOS, so that better treatment plans can be developed and the standard of living for women having this condition may improve. This condition is diagnosed using three separate criteria. Rotterdam criterion is mostly utilized for PCOS diagnosis. Different symptoms of PCOS are treated in different ways. It’s imperative to comprehensively treat these patients as soon a...
HUMAN REPRODUCTION, 2004
Since the 1990 NIH-sponsored conference on polycystic ovary syndrome (PCOS), it has become appreciated that the syndrome encompasses a broader spectrum of signs and symptoms of ovarian dysfunction than those defined by the original diagnostic criteria. The 2003 Rotterdam consensus workshop concluded that PCOS is a syndrome of ovarian dysfunction along with the cardinal features hyperandrogenism and polycystic ovary (PCO) morphology. PCOS remains a syndrome and, as such, no single diagnostic criterion (such as hyperandrogenism or PCO) is sufficient for clinical diagnosis. Its clinical manifestations may include: menstrual irregularities, signs of androgen excess, and obesity. Insulin resistance and elevated serum LH levels are also common features in PCOS. PCOS is associated with an increased risk of type 2 diabetes and cardiovascular events.
Hormonal Profile of Polycystic Ovary Syndrome (PCOS) In Indian Women
2012
Hormonal profile of PCOS was studied in 102 Indian women. Serum levels of Luteinizing hormone (LH), Follicle stimulating hormone (FSH), LH:FSH ratio, Prolactin (PRL), Thyroid stimulating hormone (TSH), Dehydroepiandrosterone (DHEA), Testosterone, fasting blood glucose (FBG), fasting insulin levels and Homeostasis Model Assessment (HOMA) value were estimated. The mean LH and FSH levels are 12.54 ± 5.87 and 5.70 ± 1.80 (IU/L) respectively. The mean LH : FSH ratio is reversed and is more than two (2.23±0.94). Mean PRL, TSH, and testosterone levels show normal ranges. Mean fasting insulin (16.27±13.27 mU/ml) and HOMA (3.509±2.621) are high with 79.31% prevalence of insulin resistance. In all the patients, both LH and FSH are positively correlated with testosterone. In normal weight patients, PRL and LH: FSH are positively correlated. In overweight/obese serum LH and DHEA are positively correlated. A positive correlation is observed between testosterone and PRL in overweight/obese. On su...
A Clinical Study on PCOS Patients in a Tertiary Hospital
Medicine Today, 2010
Polycystic ovary syndrome (PCOS) is a common condition characterized by menstrual abnormalities and clinical or biochemical features of hyperandrogenism and may manifest at any age. The present study was carried out at Bangabandhu Sheikh Mujib Medical University, Dhaka, from January 2008 to March 2009, on 50 women with PCOS which was diagnosed by three criteria: (1) oligo and/or anovulation, (2) hyperandrogenism and (3) polycystic ovaries, to evaluate their characteristics and laboratory investigation findings. Most common age was 2125 years (44%), mean BMI 27.10 kg/m2, menstrual cycle irregularity 80%, oligomenorrhoea 28%, dysmenorrhoea 18%, nulliparity 90%, history of abortion 10%, acne in 52%, hirsutism in 50%, and per vaginal findings were anteverted uterus 100%, free fornices 98% and healthy cervix 94%. Laboratory findings were low (2.8 mIU/ml) serum FSH 2%, raised (>14.7 mIU/ml) serum LH 56%, raised (7.8 mmol/L) blood sugar (2hr after 75 g glucose load) 30%, raised (>25...
Polycystic ovary syndrome (PCOS), characterized by chronic anovulation and hyperandrogenism, is common in women of childbearing age. Most of these women also have insulin resistance, and insulin sensitizing agents-metformin and the thiazolidinediones-can restore ovulation and often fertility. Treatment of hirsutism and depression are important components of therapy. The increased risk for uterine cancer because of unopposed estrogen can be managed with progestin therapy. Women with PCOS are also at greater risk for both type 2 diabetes and cardiovascular disease.
An Observational Study on 100 Patients with Polycystic Ovarian Syndrome (PCOS)
Journal of Enam Medical College, 2014
Background: Women with polycystic ovarian syndrome (PCOS) have chronic anovulation and androgen excess not attributable to another cause. The fundamental pathophysiologic defect is unknown. Defects in LH secretion, LH/FSH ratio, amplitude of LH pulsations have been described; but the prevalence of these defects is not still clearly determined. Objective: To review the variable clinical presentations of polycystic ovarian syndrome. Materials and Methods: This observational study was carried out in Combined Military Hospitals of Jessore, Rangpur and Ghatail during November 2008 to June 2013. One hundred patients attending Gynaecology Outpatient Department (GOPD) having at least two of the following criteria hyperandrogenism, chronic oligo- or anovulation and ultrasonographic findings were selected. In all selected women LH and FSH serum levels were determined and LH/FSH ratios were calculated. Body mass index (BMI) was measured and was scored to classify their state of obesity. The ...