Reversible protein precipitation to ensure stability during encapsulation within PLGA microspheres (original) (raw)

Improved Enzyme Activity and Stability in Polymer Microspheres by Encapsulation of Protein Nanospheres

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Effect of additives on the release of a model protein from PLGA microspheres

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Protein Encapsulation into PLGA Nanoparticles by a Novel Phase Separation Method Using Non-Toxic Solvents

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Effect of various additives and polymers on lysozyme release from PLGA microspheres prepared by an s/o/w emulsion technique

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Preparing Poly (Lactic-co-Glycolic Acid) (PLGA) Microspheres Containing Lysozyme-Zinc Precipitate Using a Modified Double Emulsion Method

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FTIR characterization of the secondary structure of proteins encapsulated within PLGA microspheres1An article of related interest has been published by Yang et al. in J. Pharm. Sci., 88(2), Feb. 1999, accepted Nov. 1998.1

Kai Griebenow

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Effect of the molecular weight of poly(ethylene glycol) used as emulsifier on α-chymotrypsin stability upon encapsulation in PLGA microspheres

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The influence of protein solubilisation, conformation and size on the burst release from poly(lactide-co-glycolide) microspheres

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Development of polylactide microspheres for protein encapsulation and delivery

Thomas Chandy

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Reservoir-Type Microcapsules Prepared by the Solvent Exchange Method: Effect of Formulation Parameters on Microencapsulation of Lysozyme

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Two-step nanoprecipitation for the production of protein-loaded PLGA nanospheres

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Results in Pharma Sciences, 2012

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Non-aqueous encapsulation of excipient-stabilized spray-freeze dried BSA into poly(lactide-co-glycolide) microspheres results in release of native protein

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Protein encapsulation within poly(ethylene glycol)-coated nanospheres. II. Controlled release properties

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Controlled Release of Lysozyme from Double-Walled Poly(Lactide-Co-Glycolide) (PLGA) Microspheres

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Encapsulation of bovine serum albumin in poly(lactide-co-glycolide) microspheres by the solid-in-oil-in-water technique

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Polysaccharides-based spray-dried microspheres for maintained stability and controlled release of protein

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Chemical and spatial analysis of protein loaded PLGA microspheres for drug delivery applications

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Encapsulation of lysozyme in a biodegradable polymer by precipitation with a vapor-over-liquid antisolvent

Kenji Mishima

Journal of Pharmaceutical Sciences, 1999

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A potential approach for decreasing the burst effect of protein from PLGA microspheres

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Journal of Pharmaceutical Sciences, 2003

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Preparation of protein-loaded-PLGA microspheres by an emulsion/solvent evaporation process employing LTCC micromixers

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Protein bioactivity and polymer orientation is affected by stabilizer incorporation for double-walled microspheres

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Journal of Controlled Release, 2010

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Effect of cyclodextrins on α-chymotrypsin stability and loading in PLGA microspheres upon S/O/W encapsulation

Kai Griebenow

Journal of Pharmaceutical Sciences, 2006

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Effect of salts on lysozyme stability at the water–oil interface and upon encapsulation in poly(lactic-co-glycolic) acid microspheres

Kai Griebenow

Biotechnology and Bioengineering, 2003

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Prevention of structural perturbations and aggregation upon encapsulation of bovine serum albumin into poly(lactide-co-glycolide) microspheres using the solid-in-oil-in-water technique

Kai Griebenow

Journal of Pharmacy and Pharmacology, 2001

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One-Step Production of Protein-Loaded PLGA Microparticles via Spray Drying Using 3-Fluid Nozzle

Camilla Foged

Pharmaceutical Research, 2014

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Molecular Mechanism of Improved Structural Integrity of Protein in Polymer Based Microsphere Delivery System

Sanjay Rawat

Molecular Pharmaceutics, 2012

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Effective protein release from PEG/PLA nano-particles produced by compressed gas anti-solvent precipitation techniques

Stefano Salmaso

Journal of Controlled Release, 2004

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