A new function for the fragile X mental retardation protein in regulation of PSD-95 mRNA stability (original) (raw)
The fragile X mental retardation protein and group I metabotropic glutamate receptors regulate levels of mRNA granules in brain
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Proceedings of The National Academy of Sciences, 2005
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Fragile X Mental Retardation Protein Targets G Quartet mRNAs Important for Neuronal Function
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Microarray Identification of FMRP-Associated Brain mRNAs and Altered mRNA Translational Profiles in Fragile X Syndrome
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Dysregulated Metabotropic Glutamate Receptor-Dependent Translation of AMPA Receptor and Postsynaptic Density-95 mRNAs at Synapses in a Mouse Model of Fragile X Syndrome
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The Journal of Neuroscience, 2007
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Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation
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role of FMRP in regulating translation in
Amir Ahmadian
2003
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FMRP acts as a key messenger for dopamine modulation in the forebrain
Min Zhuo
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Impaired activity-dependent FMRP translation and enhanced mGluR-dependent LTD in Fragile X premutation mice
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Cell Type-Specific mRNA Dysregulation in Hippocampal CA1 Pyramidal Neurons of the Fragile X Syndrome Mouse Model
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The fragile X mental retardation protein–RNP granules show an mGluR-dependent localization in the post-synaptic spines
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Molecular and Cellular Neuroscience, 2007
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Fragile X mental retardation protein regulates translation by binding directly to the ribosome
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Advances in understanding of fragile X pathogenesis and FMRP function, and in identification of X linked mental retardation genes
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Function of FMRP domains in regulating distinct roles of neuronal protein synthesis
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Ultrastructural analysis of the functional domains in FMRP using primary hippocampal mouse neurons
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Neurobiology of Disease, 2009
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FXR2P Exerts a Positive Translational Control and Is Required for the Activity-Dependent Increase of PSD95 Expression
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015
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A Novel Function for Fragile X Mental Retardation Protein in Translational Activation
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Mutational Analysis Establishes a Critical Role for the N Terminus of Fragile X Mental Retardation Protein FMRP
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Journal of Neuroscience, 2008
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Fragile X Related Protein 1 Clusters with Ribosomes and Messenger RNAs at a Subset of Dendritic Spines in the Mouse Hippocampus
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Fragile X mental retardation protein interactions with a G quadruplex structure in the 3′-untranslated region of NR2B mRNA
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Molecular BioSystems, 2015
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The Fragile X Mental Retardation Protein FMRP Binds Elongation Factor 1A mRNA and Negatively Regulates Its Translation in Vivo
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Journal of Biological Chemistry, 2003
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Dephosphorylation-Induced Ubiquitination and Degradation of FMRP in Dendrites: A Role in Immediate Early mGluR-Stimulated Translation
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012
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The Fragile X Mental Retardation Protein Regulates Matrix Metalloproteinase 9 mRNA at Synapses.pdf
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Fmr1 deficiency promotes age-dependent alterations in the cortical synaptic proteome
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Proceedings of the National Academy of Sciences of the United States of America, 2015
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FXR1P Limits Long-Term Memory, Long-Lasting Synaptic Potentiation, and De Novo GluA2 Translation
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FMRP-Driven Neuropathology in Autistic Spectrum Disorder and Alzheimer's disease: A Losing Game
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Frontiers in Molecular Biosciences, 2021
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Fragile X-like behaviors and abnormal cortical dendritic spines in Cytoplasmic FMR1-interacting protein 2-mutant mice
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Fragile X Mental Retardation Protein: Many Partners and Multiple Targets for a Promiscuous Function
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