8-Cl-cAMP antagonizes mitogen-activated protein kinase activation and cell growth stimulation induced by epidermal growth factor (original) (raw)
Up-regulated EGF receptors undergo to rapid internalization and ubiquitin-dependent degradation in human cancer cells exposed to 8-Cl-cAMP
Alfredo Budillon
FEBS Letters, 1999
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cAMP-mediated Growth Inhibition in Fibroblasts Is Not Mediated via Mitogen-activated Protein (MAP) Kinase (ERK) Inhibition. cAMP-DEPENDENT PROTEIN KINASE INDUCES A TEMPORAL SHIFT IN GROWTH FACTOR-STIMULATED MAP KINASES
Jacques Pouysségur
Journal of Biological Chemistry, 1996
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Elisa Grassi
PLOS One, 2011
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Antitumor Activity of Combined Blockade of Epidermal Growth Factor Receptor and Protein Kinase A
Roberto Bianco
JNCI Journal of the National Cancer Institute, 1996
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Epidermal growth factor receptor levels are reduced in mice with targeted disruption of the protein kinase A catalytic subunit
Anne-katrine Kvissel
BMC Cell Biology, 2008
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Involvement of AMP-activated protein kinase and p38 mitogen-activated protein kinase in 8-Cl-cAMP-induced growth inhibition
Navin Viswakarma
Journal of Cellular Physiology, 2009
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Epidermal growth factor (EGF) receptor kinase-independent signaling by EGF
Lark Wong
2001
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Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with In Vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785)
Ramaswamy Nilakantan
Biochemical Pharmacology, 1999
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Evaluation of Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors
Marc Lippman
Breast Cancer Research and Treatment, 2004
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Differential Modulation of Mitogen-activated Protein (MAP) Kinase/Extracellular Signal-related Kinase Kinase and MAP Kinase Activities by a Mutant Epidermal Growth Factor Receptor
David Moscatello
Journal of Biological Chemistry, 1995
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Biochemical Characterization of Extracellular cAMP-Dependent Protein Kinase as a Tumor Marker
saleh mohamed
Biochemical and Biophysical Research Communications, 2000
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Stimulation of Mitogenic Pathways through Kinase-Impaired Mutants of the Epidermal Growth Factor Receptor
Jonathan Ewald
Experimental Cell Research, 2001
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Effects of MAP kinase inhibitors on epidermal growth factor-induced neoplastic transformation of human keratinocytes
Yong Yeon Cho
Molecular Carcinogenesis, 2005
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Identification of a human epidermal growth factor receptor-associated protein kinase as a new member of the mitogen-activated protein kinase/extracellular signal-regulated protein kinase family
Steven Pelech
Journal of Biological Chemistry, 1993
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cAMP abrogates the p21ras-mitogen-activated protein kinase pathway in fibroblasts
Kees Jalink
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Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals
Václav Maťoška
The EMBO Journal, 1993
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Daniela Mari
Cancer Biology & Therapy, 2009
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Priority paper Fibroblast growth factor-2 has opposite effects on human breast cancer MCF-7 cell growth depending on the activation level of the mitogen-activated protein kinase pathway
Tarik Issad
European Journal of Biochemistry, 1998
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Activation of the Ras/Mitogen-Activated Protein Kinase Pathway by Kinase-Defective Epidermal Growth Factor Receptors Results in Cell Survival but Not Proliferation
Normand Pouliot
1998
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Inhibition of growth of primary human tumour cell cultures by a 4-anilinoquinazoline inhibitor of the epidermal growth factor receptor family of tyrosine kinases
Karen Holdaway
European Journal of Cancer, 1998
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Epidermal growth factor induces rapid tyrosine phosphorylation of proteins in A431 human tumor cells
Tony Hunter
Cell, 1981
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Activated Extracellular Signal-regulated Kinases: Association with Epidermal Growth Factor Receptor/Transforming Growth Factor Expression in Head and Neck Squamous Carcinoma and Inhibition by Anti-Epidermal Growth Factor Receptor Treatments1
Judit Anido
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8-Chloro-cyclic AMP inhibits autocrine and angiogenic growth factor production in human colorectal and breast cancer
Roberta Caputo
Clinical cancer research : an official journal of the American Association for Cancer Research, 1997
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Elevated intracellular cAMP concentration mediates growth suppression in glioma cells
Dewi ayu Safitri
2019
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Blockade of the epidermal growth factor receptor tyrosine kinase suppresses tumorigenesis in MMTV/Neu + MMTV/TGF-alpha bigenic mice
A. Lenferink
Proceedings of the National Academy of Sciences, 2000
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Isolation and characterization of two growth factor-stimulated protein kinases that phosphorylate the epidermal growth factor receptor at threonine 669
Fernando Gonzalez
The Journal of biological chemistry, 1991
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Identification of epidermal growth factor Thr-669 phosphorylation site peptide kinases as distinct MAP kinases and p34cdc2
David Warburton
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1992
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8-Chloro-cAMP induces apoptotic cell death in a human mammary carcinoma cell (MCF-7) line
Olav Vintermyr
1995
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Large-scale purification and characterisation of a recombinant epidermal growth-factor receptor protein-tyrosine kinase. Modulation of activity by multiple factors
Helmut Mett
European Journal of Biochemistry, 1992
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Pituitary Adenylate Cyclase-Activating Polypeptide Causes Tyrosine Phosphorylation of the Epidermal Growth Factor Receptor in Lung Cancer Cells
Lisa Ridnour
Journal of Pharmacology and Experimental Therapeutics, 2012
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Involvement of the cAMP/protein kinase A pathway and of mitogen-activated …
Manuel Guzman
FEBS letters
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