original ) (raw )Interference of Glycine Transporter 1: Modulation of Cognitive Functions Via Activation of Glycine-B Site of the NMDA Receptor
Benjamin K Yee
Central Nervous System Agents in Medicinal Chemistry, 2007
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Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels
Marzia Martina
Journal of Physiology-london, 2004
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Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo
Long Chen
Journal of neurophysiology, 2003
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Enhancement of the NMDA receptor function by reduction of glycine transporter-1 expression
Daniela Alberati
Neuroscience Letters, 2004
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Gene knockout of glycine transporter 1: Characterization of the behavioral phenotype
Marzia Martina
Proceedings of The National Academy of Sciences, 2004
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Reduced glycine transporter type 1 expression leads to major changes in glutamatergic neurotransmission of CA1 hippocampal neurones in mice
Marzia Martina
Journal of Physiology-london, 2005
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The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia
Joseph T Coyle
Psychopharmacology, 2004
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Glycine transporters: crucial roles of pharmacological interest revealed by gene deletion
Beatriz López-Corcuera
Trends in Pharmacological Sciences, 2005
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Blockade of glycine transporter 1 by SSR504734 promotes cognitive flexibility in glycine/NMDA receptor-dependent manner
Dominik Rafa
Neuropharmacology, 2011
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Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant nonhabituating hyperactivity
Vincent Mutel
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002
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Localization of the GLYT1 Glycine Transporter at Glutamatergic Synapses in the Rat Brain
F. Zafra
Cerebral Cortex, 2005
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Prepulse inhibition deficits of the startle reflex in neonatal ventral hippocampal–lesioned rats: reversal by glycine and a glycine transporter inhibitor
Daniela Alberati , Edilio Borroni
Biological Psychiatry, 2003
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Cloning and expression of a glycine transporter from mouse brain
Nathan Nelson
FEBS Letters, 1992
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Activation of the glycine site in the NMDA receptor is necessary for the induction of LTP
graham collingridge
Neuroscience Letters, 1990
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High concentrations of glycine induce long-lasting changes in synaptic efficacy in rat hippocampal slices
Michel Baudry
Neuroscience Letters, 1993
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A NMDA receptor glycine site partial agonist, GLYX-13, simultaneously enhances LTP and reduces LTD at Schaffer collateral–CA1 synapses in hippocampus
Patric Stanton , Joseph Moskal , Xiao-lei Zhang
Neuropharmacology, 2008
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L-687,414, a low efficacy NMDA receptor glycine site partial agonist in vitro, does not prevent hippocampal LTP in vivo at plasma levels known to be neuroprotective
Tony Priestley , Raymond Hill
British Journal of Pharmacology, 1998
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The cognitive effects of modulating the glycine site of the NMDA receptor with high-dose glycine in healthy controls
Pradeep Nathan
Human Psychopharmacology: Clinical and Experimental, 2008
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Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site
Gerhard Trube , Vincent Mutel
The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000
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Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity level
Silvia Sacchi
Nature Communications, 2013
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Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia☆
Guy Griebel
Pharmacology Biochemistry and Behavior, 2008
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Glycine action on receptors in rat hippocampal neurons
O. Krishtal
Neuroscience Letters, 1989
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Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia: latent inhibition studies in the rat
Michal Arad
Psychopharmacology, 2009
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Glycine site associated with the NMDA receptor modulates long-term potentiation
Frank Schottler
Synapse, 1990
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Glycine transporters: essential regulators of synaptic transmission
Volker Eulenburg
Biochemical Society Transactions, 2006
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Neurotransmitters: NMDA receptors: do glia hold the key?
Stuart Cull-candy
Current Biology, 1995
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Molecular biology of glycinergic neurotransmission
F. Zafra
Molecular Neurobiology, 1997
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