Glycine transporters: crucial roles of pharmacological interest revealed by gene deletion (original) (raw)

Interference of Glycine Transporter 1: Modulation of Cognitive Functions Via Activation of Glycine-B Site of the NMDA Receptor

Benjamin K Yee

Central Nervous System Agents in Medicinal Chemistry, 2007

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Enhancement of the NMDA receptor function by reduction of glycine transporter-1 expression

Daniela Alberati

Neuroscience Letters, 2004

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Localization of the GLYT1 Glycine Transporter at Glutamatergic Synapses in the Rat Brain

F. Zafra

Cerebral Cortex, 2005

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Molecular biology of glycinergic neurotransmission

F. Zafra

Molecular Neurobiology, 1997

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Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels

Marzia Martina

Journal of Physiology-london, 2004

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Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo

Long Chen

Journal of neurophysiology, 2003

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Gene knockout of glycine transporter 1: Characterization of the behavioral phenotype

Marzia Martina

Proceedings of The National Academy of Sciences, 2004

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Glycine transporters: essential regulators of synaptic transmission

Volker Eulenburg

Biochemical Society Transactions, 2006

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Glycine as a neurotransmitter in the forebrain: a short review

Lanfranco R P Troncone

Journal of neural transmission (Vienna, Austria : 1996), 2009

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Localization of Glycine Neurotransmitter Transporter (GLYT2) Reveals Correlation with the Distribution of Glycine Receptor

Nathan Nelson

Journal of Neurochemistry, 2002

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Glycine action on receptors in rat hippocampal neurons

O. Krishtal

Neuroscience Letters, 1989

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Glycine transporters are differentially expressed among CNS cells

F. Zafra

The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995

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Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses

Stéphane Dieudonné, Philippe Ascher

Journal of neurophysiology, 1998

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Cloning and expression of a glycine transporter from mouse brain

Nathan Nelson

FEBS Letters, 1992

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Activation of the glycine site in the NMDA receptor is necessary for the induction of LTP

graham collingridge

Neuroscience Letters, 1990

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Identity of endogenous NMDAR glycine site agonist in amygdala is determined by synaptic activity level

Silvia Sacchi

Nature Communications, 2013

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Development of synaptic inhibition in glycine transporter 2 deficient mice

Volker Eulenburg

Molecular and Cellular Neuroscience, 2010

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Antagonists and agonists at the glycine site of the NMDA receptor for therapeutic interventions

Gerd Dannhardt

European Journal of Medicinal Chemistry, 2003

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Neurotransmitters: NMDA receptors: do glia hold the key?

Stuart Cull-candy

Current Biology, 1995

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The glycine receptor

Lynch Peter

Pharmacology & Therapeutics, 1997

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Modulation of glycine receptor function: a novel approach for therapeutic intervention at inhibitory synapses?

Bodo Laube

Trends in Pharmacological Sciences, 2002

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Reduced glycine transporter type 1 expression leads to major changes in glutamatergic neurotransmission of CA1 hippocampal neurones in mice

Marzia Martina

Journal of Physiology-london, 2005

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Synergistic Control of Transmitter Turnover at Glycinergic Synapses by GlyT1, GlyT2 and ASC-1

Volker Eulenburg

International Journal of Molecular Sciences, 2022

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The discovery of a structurally novel class of inhibitors of the type 1 glycine transporter

John Lowe

Bioorganic & Medicinal Chemistry Letters, 2009

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The glycine transporter GLYT2 is a reliable marker for glycine-immunoreactive neurons

F. Zafra, Irene Poyatos

Molecular Brain Research, 1997

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Electrophysiological Analysis of the Modulation of NMDA-Receptors Function by d-Serine and Glycine in the Central Nervous System

Glenn Dallérac, Jean-pierre Mothet

Methods in Molecular Biology, 2011

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The Inhibitory Glycine Receptor—Simple Views of a Complicated Channel

Hans-Georg Breitinger

ChemBioChem, 2002

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Glycine-dependent activation of NMDA receptors

Gabriela K Popescu

The Journal of general physiology, 2015

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Glycine Site Agonists of the NMDA Receptor: A Review

John Krystal

CNS Drug Reviews, 1995

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Glycine taken up through GLYT1 and GLYT2 heterotransporters into glutamatergic axon terminals of mouse spinal cord elicits release of glutamate by homotransporter reversal and through anion channels

Antonella Termine

Biochemical Pharmacology, 2005

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