NGF and ProNGF: Regulation of neuronal and neoplastic responses through receptor signaling (original) (raw)

The trk tyrosine protein kinase mediates the mitogenic properties of nerve growth factor and neurotrophin-3

Shuqian Jing

Cell, 1991

View PDFchevron_right

Biological Activity of Nerve Growth Factor Precursor Is Dependent upon Relative Levels of Its Receptors

Shelley Allen

Journal of Biological Chemistry, 2009

View PDFchevron_right

ProNGF, but Not NGF, Switches from Neurotrophic to Apoptotic Activity in Response to Reductions in TrkA Receptor Levels

Margaret Fahnestock

International journal of molecular sciences, 2017

View PDFchevron_right

The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor

Margaret Fahnestock

Journal of Neurochemistry, 2004

View PDFchevron_right

Transcriptional down-regulation of epidermal growth factor (EGF) receptors by nerve growth factor (NGF) in PC12 cells

Keren Ettinger, Gadi Cohen, Philip Lazarovici

Journal of molecular neuroscience : MN, 2014

View PDFchevron_right

Fibroblast Growth Factor Receptors Participate in the Control of Mitogen-activated Protein Kinase Activity during Nerve Growth Factor-induced Neuronal Differentiation of PC12 Cells

Andreas Bikfalvi

Journal of Biological Chemistry, 1999

View PDFchevron_right

Expression of the nerve growth factor receptors TrkA and p75 in malignant mesothelioma

Philip Lazarovici

Lung Cancer, 2004

View PDFchevron_right

The trkA receptor mediates growth cone turning toward a localized source of nerve growth factor

Paul Letourneau

The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997

View PDFchevron_right

TrkA Tyrosine Residues Involved in NGF-induced Neurite Outgrowth of PC12 Cells

Dan Lindholm

European Journal of Neuroscience, 1995

View PDFchevron_right

Two Restricted Sites on the Surface of the Nerve Growth Factor Molecule Independently Determine Specific TrkA Receptor Binding and Activation

Ted Ebendal

Journal of Biological Chemistry, 1997

View PDFchevron_right

TrkA receptor mediates growth cone turning toward a localized source of nerve growth factor

Paul Letourneau

The Journal of Neuroscience : The Official Journal of the Society for Neuroscience

View PDFchevron_right

Characterization and growth-dependent regulation of the nerve growth factor receptor gp140trk in rat C6 glioma cells

Roberto Dal Toso

Molecular Brain Research, 1994

View PDFchevron_right

Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3

Susan Meakin

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2006

View PDFchevron_right

Nerve growth factor employs multiple pathways to induce primary response genes in PC12 cells

Cinzia Volonté

Molecular Biology of the Cell, 1992

View PDFchevron_right

Differential Activity of the Nerve Growth Factor (NGF) Antagonist PD90780 [7-(Benzolylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic Acid] Suggests Altered NGF-p75NTR Interactions in the Presence of TrkA

Igor Shamovsky

Journal of Pharmacology and Experimental Therapeutics, 2004

View PDFchevron_right

Nerve Growth Factor Stimulates Multisite Tyrosine Phosphorylation and Activation of the Atypical Protein Kinase C's via a src Kinase Pathway

Lamar Seibenhener

Molecular and Cellular Biology, 2001

View PDFchevron_right

On the role of the low-affinity neurotrophin receptor p75LNTR in nerve growth factor induction of differentiation and AP 1 binding activity in PC12 cells

Ewa Kontny

Journal of Molecular Neuroscience, 1997

View PDFchevron_right

A Novel p75 Neurotrophin Receptor-Related Protein, NRH2, Regulates Nerve Growth Factor Binding to the TrkA Receptor

Pilar Perez

Journal of Neuroscience, 2004

View PDFchevron_right

A Kinase Insert Isoform of Rat TrkA Supports Nerve Growth Factor-Dependent Cell Survival but Not Neurite Outgrowth

Ela Gryz

Journal of Neurochemistry, 2002

View PDFchevron_right

Nerve growth factor induced stimulation of Ras requires Trk interaction with Shc but does not involve phosphoinositide 3-OH kinase.

David Loeb

Oncogene, 1998

View PDFchevron_right

Mapping of Atypical Protein Kinase C within the Nerve Growth Factor Signaling Cascade: Relationship to Differentiation and Survival of PC12 Cells

Lamar Seibenhener

Molecular and Cellular Biology, 2000

View PDFchevron_right

Nerve growth factor as potential target in central nervous system disorders: A review

World Journal of Pharmaceutical Sciences

View PDFchevron_right

Competitive signaling between TrkA and p75 nerve growth factor receptors determines cell survival

Patrizia Casaccia

The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998

View PDFchevron_right

Nerve growth factor promotes activation of the alpha, beta and gamma isoforms of protein kinase B in PC12 pheochromocytoma cells

mirjana andjelkovic

European Journal of Biochemistry, 1998

View PDFchevron_right

Autocrine regulation of nerve growth factor expression by Trk receptors

Alessandra Mallei

Journal of Neurochemistry, 2004

View PDFchevron_right

Cell cycle phase-specific surface expression of nerve growth factor receptors TrkA and p75(NTR)

D. Martín-zanca, Muriel Andrieu

The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998

View PDFchevron_right

Association of protein kinases ERK1 and ERK2 with p75 nerve growth factor receptors

Cinzia Volonté

The Journal of biological chemistry, 1993

View PDFchevron_right

A quantitative bioassay for nerve growth factor, using PC12 clones expressing different levels of trkA receptors

Dalia Shabashov, Philip Lazarovici

2002

View PDFchevron_right

NF-κB Signaling Promotes Both Cell Survival and Neurite Process Formation in Nerve Growth Factor-Stimulated PC12 Cells

Erik Foehr

The Journal of Neuroscience

View PDFchevron_right

A TrkA-selective, Fast Internalizing Nerve Growth Factor-Antibody Complex Induces Trophic but Not Neuritogenic Signals

Amine Kamen

Journal of Biological Chemistry, 1998

View PDFchevron_right