Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells (original) (raw)
Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1 and regulatory T cell induction
Mark Boothby
2013
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The TSC-mTOR Signaling Pathway Regulates the Innate Inflammatory Response
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Convergence of the Mammalian Target of Rapamycin Complex 1-and Glycogen Synthase Kinase 3-�����Signaling Pathways Regulates the Innate Inflammatory Response
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Toll-like receptor–mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway
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Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony
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Rapamycin Induces Mitogen-activated Protein (MAP) Kinase Phosphatase-1 (MKP-1) Expression through Activation of Protein Kinase B and Mitogen-activated Protein Kinase Kinase Pathways
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Multifaceted role of mTOR (mammalian target of rapamycin) signaling pathway in human health and disease
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Interleukin-6 influences stress-signalling by reducing the expression of the mTOR-inhibitor REDD1 in a STAT3-dependent manner
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Rapamycin Blocks IL-2-Driven T Cell Cycle Progression While Preserving T Cell Survival
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Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes
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The emerging role of microRNA in regulating the mTOR signaling pathway in immune and inflammatory responses
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Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling
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Converging TLR9 and PI3Kgamma signaling induces sterile inflammation and organ damage
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mTORC1-S6K Activation by Endotoxin Contributes to Cytokine Up-Regulation and Early Lethality in Animals
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Differential modulation of the cytokine-induced MMP-9/TIMP-1 protease–antiprotease system by the mTOR inhibitor rapamycin
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Mammalian target of rapamycin inhibition in macrophages of asymptomatic HIV+ persons reverses the decrease in TLR-4-mediated TNF-α release through prolongation of MAPK pathway activation
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A Role for Mammalian Target of Rapamycin in Regulating T Cell Activation versus Anergy
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TLR Crosstalk Activates LRP1 to Recruit Rab8a and PI3Kγ for Suppression of Inflammatory Responses
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mTOR Regulation of Lymphoid Cells in Immunity to Pathogens
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The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists
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Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR)
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mTOR Signaling pathway as a master regulator of memory CD8+ T‐cells, Th17, and NK cells development and their functional properties
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mTOR-Mediated Regulation of Immune Responses in Cancer and Tumor Microenvironment
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The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock
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TIRAP/Mal Positively Regulates TLR8-Mediated Signaling via IRF5 in Human Cells
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mTOR: A Cellular Regulator Interface in Health and Disease
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RIP1 is an essential mediator of Toll-like receptor 3–induced NF-κB activation
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