Interleukin-7 is a critical growth factor in early human T-cell development (original) (raw)
Differential IL-7 responses in developing human thymocytes
Justin Van De Wiele
Human Immunology, 2010
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Effects of IL-7 on Early Human Thymocyte Progenitor Cells In Vitro and in SCID-hu Thy/Liv Mice
Mary Beth Hanley
The Journal of Immunology, 2003
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IL-7 Enhances Thymic Human T Cell Development in "Human Immune System" Rag2-/-IL-2R c-/- Mice without Affecting Peripheral T Cell Homeostasis
Arjen Bakker
The Journal of Immunology, 2009
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Distinct Requirements for IL-7 in Development of TCR Cells During Fetal and Adult Life
Robert Tigelaar
The Journal of Immunology, 2003
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Tracing the expression of CD7 and other antigens during T- and myeloid-cell differentiation in the human fetal liver and thymus
Marcus O Muench
Leukemia & lymphoma, 1995
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Distinct Requirements for IL-7 in Development of TCRγδ Cells During Fetal and Adult Life
Robert Tigelaar
Journal of Immunology, 2003
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CD34-expressing human thymocyte precursors proliferate in response to interleukin-7 but have lost myeloid differentiation potential
Claudine Schmitt
Blood, 1993
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IL-7 Produced by Thymic Epithelial Cells Plays a Major Role in the Development of Thymocytes and TCR + Intraepithelial Lymphocytes
Georg Holländer
The Journal of Immunology, 2013
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Interleukin 7 receptor engagement stimulates tyrosine phosphorylation, inositol phospholipid turnover, proliferation, and selective differentiation to the CD4 lineage by human fetal thymocytes
Ilker Dibirdik
Proceedings of the National Academy of Sciences, 1991
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Ontogeny and regulation of IL-7-expressing thymic epithelial cells
Nancy Manley
Journal of immunology (Baltimore, Md. : 1950), 2005
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Overexpression of IL-7Rα provides a competitive advantage during early T-cell development
Yasmina Laouar
Blood, 2004
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TCR{gamma}{delta} Cells Extrathymic Development of The Role of IL7 in Thymic and
Ma Lak
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Interleukin‐7 treatment promotes the differentiation pathway of T‐cell‐receptor‐αβ cells selectively to the CD8 + cell lineage
John Munoz
Immunology, 1997
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Regulation of in vitro human T cell development through interleukin-7 deprivation and anti-CD3 stimulation
Jan Moreb
BMC Immunology, 2012
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Intrathymic IL-7: The where, when, and why of IL-7 signaling during T cell development
Changwan Hong
Seminars in Immunology, 2012
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New insights into IL-7 signaling pathways during early and late T cell development
Xuebin Qin
Cellular & Molecular Immunology, 2013
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Ontogeny and Regulation of IL7Expressing Thymic Epithelial Cells1
Nancy Manley
2000
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Interleukin-7 supports survival of T-cell receptor-β-expressing CD4 − CD8 − double-negative thymocytes
Thomas Yankee
Immunology, 2013
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Presence of CD8 alpha-CD8 beta-positive TcR gamma/delta thymocytes in the fetal murine thymus and their in vitro expansion with interleukin-7
Georges Leclercq, Jean Plum
European Journal of Immunology
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Interleukin‐7 in the transition of bone marrow progenitors to the thymus
Abdalla Sheikh
Immunology & Cell Biology, 2017
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Presence of CD8α-CD8β-positive TcR γ/δ thymocytes in the fetal murine thymus and theirin vitro expansion with interleukin-7
Jean Plum
European Journal of Immunology, 1992
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Treatment of fetal thymic organ culture with IL-1 leads to accelerated differentiation of subsets of CD4−CD8− cells
Gary Waanders
Cellular Immunology, 1992
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Origin, phenotype and autoimmune potential of T cells in human immune system mice receiving neonatal human thymus tissue
Megan Sykes
Frontiers in Immunology
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IL-7-Induced Proliferation of Human Naive CD4 T-Cells Relies on Continued Thymic Activity
Rui Anjos
Frontiers in immunology, 2017
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Dynamic regulation of IL-7 receptor expression is required for normal thymopoiesis
I. Munitic
Blood, 2004
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Responsiveness of fetal and adult CD4-, CD8- thymocytes to T cell activation
William Gause
The Journal of Immunology
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IL-7 Receptor Signals Inhibit Expression of Transcription Factors TCF-1, LEF-1, and ROR t: Impact on Thymocyte Development
B. Erman
Journal of Experimental Medicine, 2004
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Molecular and functional evidence for activity of murine IL-7 on human lymphocytes
Joao Barata
Experimental …, 2006
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Characterization of the thymic IL-7 niche in vivo
L. Peduto, Ana Cumano, Richard Boyd
Proceedings of the National Academy of Sciences, 2009
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