Studies on the mechanism of 3-deazaguanine cytotoxicity in L1210-sensitive and -resistant cell lines
Bach Ardalan
Cancer Chemotherapy and Pharmacology, 1988
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Potentiation of CB 1954 cytotoxicity by reduced pyridine nucleotides in human tumour cells by stimulation of DT diaphorase activity
Patrick J Biggs
Biochemical Pharmacology, 1992
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Relationships between the formation of O6-methyldeoxyguanosine by 1-p-carboxyl-3,3-dimethylphenyltriazene in DNA and O6-alkylguanine-DNA alkyltransferase in human peripheral leukocytes
Siow-ming Lee
Cancer research, 1994
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Treatment of normal and malignant cells with nucleoside analogues and etoposide enhances deoxycytidine kinase activity
Staffan Eriksson, T. Spasokoukotskaja
European Journal of Cancer, 1999
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Alteration of the carbohydrate for deoxyguanosine analogs markedly changes DNA replication fidelity, cell cycle progression and cytotoxicity
Tico Thepsourinthone, Sheryl Flanagan, Brendon Ladd
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2010
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Repair of O6-alkylguanines in the nuclear DNA of human lymphocytes and leukaemic cells: analysis at the single-cell level
Michael Mueller
British Journal of Cancer, 1994
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DNA damage and differential cytotoxicity produced in human carcinoma cells by CC-1065 analogues, U-73,975 and U-77,779
Neil Gibson
Cancer research, 1991
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Genotoxic and cytotoxic effects of 4-aroyl-1-nitrosohydrazine-carboxamides onO 6-alkylguanine-DNA alkyltransferase-positive and-negative human cell lines
Evgeny Golovinsky
Journal of Cancer Research and Clinical Oncology, 1994
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Effects of the antitumor agent 8-carbamoyl-3-(2-chloroethyl)imidazo[5,1-d]-1,2,3,5-tetrazin-4(3 H)-one on the DNA of mouse L1210 cells
Neil Gibson
Cancer research, 1984
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Mechanism of inhibition of DNA synthesis in Ehrlich ascites tumour cells by diazoacetyl glycine-amide
Tullio Giraldi
Biochemical Pharmacology, 1973
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The effect of deoxyadenosine plus deoxycoformycin on replicative and repair synthesis of DNA in human lymphoblasts and isolated nuclei
Alice Yu
The Journal of biological chemistry, 1988
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Accumulation of DNA strand breaks in cells exposed to methotrexate or N10-propargyl-5,8-dideazafolic acid
Maurizio Dincalci
Cancer Research, 1988
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Detection of sequence-specific antitumor alkylating agent DNA damage from cells treated in culture and from a patient
George Ogata
Cancer research, 1994
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A mammalian cell variant in which 3-aminobenzamide does not potentiate the cytotoxicity of dimethyl sulphate
Manoochehr Tavassoli, Sydney Shall
Mutation Research/DNA Repair Reports, 1986
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DNA repair induction by cytostatic drugs in proliferating and quiescent MRC-5 cells
Romualdo Benigni
Birth Defects Research, 1983
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Deoxyribonucleoside incorporation and the role of hydroxyurea in a model system for studying DNA repair in carcinogenesis
Stewart Sell
Cancer Research
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Imbalanced DNA synthesis induced by cytosine arabinoside and fludarabine in human leukemia cells
Giuseppina Carbone
Biochemical Pharmacology, 2001
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Effect of Cytarabine and Decitabine in Combination in Human Leukemic Cell Lines
Jaroslav Jelinek
Clinical Cancer Research, 2007
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Depletion of O6-alkylguanine-DNA alkyltransferase activity in mammalian tissues and human tumor xenografts in nude mice by treatment with O6-methylguanine
Jason Yang
Cancer Chemotherapy and Pharmacology, 1989
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Metabolic activation of the tumorigenic pyrrolizidine alkaloid, monocrotaline, leading to DNA adduct formation in vivo
Richard Beger
Cancer Letters, 2005
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Transient inhibition of DNA synthesis results in increased dihydrofolate reductase synthesis and subsequent increased DNA content per cell
J. Feder
Molecular and Cellular Biology, 1986
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Formation of depurinating N3adenine and N7guanine adducts after reaction of 1,2-naphthoquinone or enzyme-activated 1,2-dihydroxynaphthalene with DNA
Muhammad Saeed
Chemico-Biological Interactions, 2007
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Characterization of DNA damage and cytotoxicity induced in two human colon carcinoma cell lines by cyclodisone
Neil Gibson
Cancer research, 1989
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DNA reactivity and in vitro cytotoxicity of the novel antitumor agent 1,5,2,4-dioxadithiepane-2,2,4,4-tetraoxide (NSC-348948) in human embryo cells
Neil Gibson
Cancer research, 1986
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Potentiation of etoposide-induced cytotoxicity and DNA damage in CCRF-CEM cells by pretreatment with non-cytotoxic concentrations of arabinosyl cytosine
Ray Hicks
Cancer Chemother Pharmacol, 1992
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Studies on DNA repair in human lymphocytes treated with proximate carcinogens and alkylating agents
Stewart Sell
Cancer Research
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Sedimentation of DNA from L1210 cells after treatment with 4'-demethylepipodophyllotoxin-9-(4,6-O-2-thenylidene-beta-D-glucopyranoside) or 1-beta-D-arabinofuranosylcytosine or both drugs
Charles Peck
Cancer research, 1980
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Resistance to fluorodeoxyuridine-induced DNA damage and cytotoxicity correlates with an elevation of deoxyuridine triphosphatase activity and failure to accumulate deoxyuridine triphosphate
Yvette Tang
Cancer research, 1993
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Role of NAD(P)H:Quinone oxidoreductase (DT-diaphorase) in cytotoxicity and induction of DNA damage by streptonigrin
Howard Beall
Biochemical Pharmacology, 1996
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Tracking Decitabine Incorporation into Malignant Myeloid Cell DNA in vitro and in vivo by LC-MS/MS with Enzymatic Digestion
Reda Mahfouz
Scientific Reports, 2019
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Cytotoxic activity and mechanism of action of 5-aza-2′-deoxycytidine in human CML cells
Valentino Conter
Leukemia Research, 1993
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DNA damage responses triggered by a highly cytotoxic monofunctional DNA alkylator, hedamycin, a pluramycin antitumor antibiotic
Thomas Melendy
Molecular cancer therapeutics, 2004
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Effects of in vivo exposure to antineoplastic drugs on DNA repair and replication in human lymphocytes
Lucia Celotti
Mutation Research Letters, 1990
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In Vitro Effects on DNA Synthesis as a Predictor of Biological Effect from Chemotherapy
Lance Heilbrun
Cancer Research, 1980
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Modulation of cytosine arabinoside toxicity by 3-deazauridine in a murine leukemia model
Steadman Harrison III
Leukemia Research, 1991
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