Antibodies, Fc receptors and cancer (original) (raw)
The interactions of therapeutic antibodies with Fc receptors
Marcello Albanesi
Immunology Letters, 2012
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Fc receptors enable anticancer action of proapoptotic and immune-modulatory antibodies
Avi Ashkenazi
Journal of Experimental Medicine, 2013
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Fc Optimization of Therapeutic Antibodies Enhances Their Ability to Kill Tumor Cells In vitro and Controls Tumor Expansion In vivo via Low-Affinity Activating Fcγ Receptors
Sergey Gorlatov
Cancer Research, 2007
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FcγR dependent mechanisms of cytotoxic, agonistic, and neutralizing antibody activities
Falk Nimmerjahn
Trends in Immunology, 2015
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Immunotherapy Targeting Inhibitory Fc Receptor IIB (CD32b) in the Mouse Is Limited by Monoclonal Antibody Consumption and Receptor Internalization
J. Verbeek, Mark Cragg
The Journal of Immunology, 2013
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A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies
Patrizia Mondello
Leukemia, 2017
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Fc Receptor Dependency of Agonistic CD40 Antibody in Lymphoma Therapy Can Be Overcome through Antibody Multimerization
Sjef Verbeek
The Journal of Immunology, 2014
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Fc-binding antibody-recruiting molecules exploit endogenous antibodies for anti-tumor immune responses
Akihiro Kishimura
Chemical Science, 2020
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CD32B, the human inhibitory Fc-γ receptor IIB, as a target for monoclonal antibody therapy of B-cell lymphoma
Sergey Gorlatov
Blood, 2006
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Advances in the assessment and control of the effector functions of therapeutic antibodies
Thomas Arroll
Nature Reviews Drug Discovery, 2011
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Fc gamma receptors and cancer
L. Cassard
Springer Seminars in Immunopathology, 2006
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Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities
Chae Reed, Yong Ying, Shan Chung, Valerie Quarmby
mAbs, 2012
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Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity …
Yong Ying
mAbs, 2012
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Combined glyco- and protein-Fc engineering simultaneously enhance cytotoxicity and half-life of a therapeutic antibody
Rémi Urbain
mAbs, 2014
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Enhanced binding of low-affinity antibodies interacting simultaneously with targeted cell surface molecules and Fc receptor
Michael Hansen
Tissue Antigens, 2002
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An Fcγ Receptor-Dependent Mechanism Drives Antibody-Mediated Target-Receptor Signaling in Cancer Cells
Dylan Lawrence
Cancer Cell, 2011
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Ligand inhibition studies on the role of Fc receptors in antibody-dependent cell-mediated cytotoxicity
M. Benczur, Gabriella Sarmay
Molecular Immunology, 1984
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Fc receptor inside-out signaling and possible impact on antibody therapy
Jeanette Leusen
Immunological Reviews, 2015
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Enhancing the potency of therapeutic monoclonal antibodies via Fc optimization
Sergey Gorlatov
Advances in Enzyme Regulation, 2008
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Chronic lymphocytic leukaemia cells are efficiently killed by an anti-CD20 monoclonal antibody selected for improved engagement of FcγRIIIA/CD16
Vincent Vieillard
British Journal of Haematology, 2008
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Evaluating Antibodies for Their Capacity to Induce Cell-mediated Lysis of Malignant B Cells1
Peisheng Hu
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FcγRIIIb Restricts Antibody-Dependent Destruction of Cancer Cells by Human Neutrophils
Robin Van Bruggen
Frontiers in Immunology, 2019
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Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields
John Maher
Frontiers in Immunology
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Evaluating antibodies for their capacity to induce cell-mediated lysis of malignant B cells
Peisheng Hu
Cancer research, 1998
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Immunotherapy Targeting Inhibitory Fcγ Receptor IIB (CD32b) in the Mouse Is Limited by Monoclonal Antibody Consumption and Receptor Internalization
Mark Cragg
The Journal of Immunology, 2013
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Monoclonal antibodies that bind to distinct epitopes on Fc gamma RI are able to trigger receptor function
Paul Guyre
Journal of Immunology, 1989
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Fc Receptors: cell activators of antibody functions
Eileen Uribe-Querol
2013
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Fc-Engineering for Modulated Effector Functions—Improving Antibodies for Cancer Treatment
Mark Cragg
Antibodies, 2020
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Fc receptor targeting in the treatment of allergy, autoimmune diseases and cancer
kenichi akiyama
Expert Opinion on Therapeutic Targets, 2005
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