Clinical and histo-morphological presentation of isolated maxillo–palatal fibromatosis (original) (raw)
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Surgical Management of a Severe Case of Gingival Fibromatosis
oral health and dental management, 2016
Gingival fibromatosis (GF) is a fibrous overgrowth of gingiva that maybe idiopathic or may have an inheritance pattern wherein it is known as hereditary gingival fibromatosis (HGF). This case report describes a 16-year old female patient who presented generalized extensive gingival overgrowth, involving the maxillary and mandibular arches. Diagnosis of GF was substantiated by the patient’s clinical features and histopathological examination. Excision of the gingival tissue was done by gingivectomy with manual instrumentation and electrosurgery. The postoperative course was uneventful and the patient’s aesthetic concerns were addressed. Thus, in severe cases of GF, the use of multiple modalities of surgery is warranted to achieve favorable esthetic and functional results.
American Journal of Case Reports, 2016
Objective: Rare disease Background: Hereditary gingival fibromatosis is characterized by slowly progressive enlargement of the gingiva that can present as an isolated condition or a part of various syndromes. Case Report: An 11-year-old female reported with a gingival lesion that caused masticatory problems and poor oral hygiene. Periodontal examination revealed a dense tissue covering 30% of her teeth crowns within both jaws. Panoramic x-ray showed a normal bone height and teeth positioning. The patient did not use any medications, but a similar condition was also present in other family members. The patient was diagnosed with hereditary gingival fibromatosis. Surgery was carried out to remove excess of gingival tissue. Post-surgical healing was uneventful, but four weeks after the first surgery, the condition recurred amounting to 45% of the initial tissue volume presenting in the mandible, and 25% in the maxilla. Two months later, no significant growth was noted in the mandible, while in the maxilla, growth increased to 40% of the pre-operative state. Analysis by polarized microscope showed a significant increase of thin fibrotic fibrils that contributed 80% of the total pool of collagen fibrils in the patient's gingiva, but only 25% in healthy gingiva. The patient was receiving outpatient care for follow-up every three months and surgical intervention had not been planned as long as her periodontal health would not be compromised. Conclusions: It is currently not clear whether the extent of the fibrosis had a mechanistic association with the ratio of gingival tissue re-growth in our case study. Further studies are needed to explain this association and improve the management of this condition.
Gingival fibromatosis: clinical, molecular and therapeutic issues
Orphanet Journal of Rare Diseases, 2016
Gingival fibromatosis is a rare and heterogeneous group of disorders that develop as slowly progressive, local or diffuse enlargements within marginal and attached gingiva or interdental papilla. In severe cases, the excess tissue may cover the crowns of the teeth, thus causing functional, esthetic, and periodontal problems, such as bone loss and bleeding, due to the presence of pseudopockets and plaque accumulation. It affects both genders equally. Hereditary, drug-induced, and idiopathic gingival overgrowth have been reported. Hereditary gingival fibromatosis can occur as an isolated condition or as part of a genetic syndrome. The pathologic manifestation of gingival fibromatosis comprises excessive accumulation of extracellular matrix proteins, of which collagen type I is the most prominent example. Mutation in the Son-of-Sevenless-1 gene has been suggested as one possible etiological cause of isolated (non-syndromic) hereditary gingival fibromatosis, but mutations in other genes are also likely to be involved, given the heterogeneity of this condition. The most attractive concept of mechanism for drug-induced gingival overgrowth is epithelial-to-mesenchymal transition, a process in which interactions between gingival cells and the extracellular matrix are weakened as epithelial cells transdifferentiate into fibrogenic fibroblast-like cells. The diagnosis is mainly made on the basis of the patient's history and clinical features, and on histopathological evaluation of affected gingiva. Early diagnosis is important, mostly to exclude oral malignancy. Differential diagnosis comprises all pathologies in the mouth with excessive gingival overgrowth. Hereditary gingival fibromatosis may present as an autosomal-dominant or less commonly autosomal-recessive mode of inheritance. If a systemic disease or syndrome is suspected, the patient is directed to a geneticist for additional clinical examination and specialized diagnostic tests. Treatments vary according to the type of overgrowth and the extent of disease progression, thus, scaling of teeth is sufficient in mild cases, while in severe cases surgical intervention is required. Prognosis is precarious and the risk of recurrence exists.
Fibroma Of The Gingiva: A Case Report Of 20 Year Long Standing Lesion
Fibroma is a common benign tumor. It can occur at any age from almost any soft tissue site the tongue, gingiva, and buccal mucosa being the most common. Females are twice as likely to develop this benign tumor than male. Typically the lesion is a rounded, well-demarcated, variably sized mass attached to tissue by a stalk. The surface is smooth, and the color is slightly paler than the adjacent healthy tissue. It is usually characterized by a slow, painless growth accumulated over a period of months or years. Treatment usually requires total excision and recurrence is rare.
Idiopathic gingival fibromatosis – case report
Idiopathic gingival enlargement is a type of gingival fibromatosis characterized by progressive overgrowth of the gingival tissues.This case report presented the clinical features of a typical idiopathic gingival enlargement which was treated with external bevel gingivactomy. The patient presented with generalized diffuse gingival enlargement involving the maxillary and mandibular arches extending on buccal and lingual/palatal surfaces and covering incisal/occlusal third of the tooth resulting in difficulty in speech and mastication since last three years. Gingivectomy was carried outto improve patient's quality of life. Since removal of hyperplastic gingival tissue eliminates difficulties in eating and speaking. Therefore, this surgical intervention improves access for plaque control, and leads to psychological benefits due to esthetic improvement. In this case, even after one year from following-up, no recurrence of gingival overgrowth was observed. Keyword: Gingival Overgrowt...
Indian Journal of Dental Research, 2011
Gingival fibromatosis is characterized by fibrotic enlargement of the gingiva that can occur as inherited or sporadic form. Inherited form can be an isolated trait or as a component of a syndrome. This article reports a 35 year old male patient affected by gingival fibromatosis associated with hemiosseous hyperplasia of mandible, maxilla, and zygoma on the right side, viral papillomatosis of maxillary anterior gingiva, fissured tongue and congenitally missing anterior teeth. The patient was subjected to phase I and phase II periodontal therapy. There was no evidence of recurrence of the enlargement after one year but the papillomatosis recurred. Gingival fibromatosis has been reported to be associated with various other abnormalities but not with those described in our case. This observation raises the possibility that the coexistence of these entities in our case may represent a new syndrome.
Study About Hereditary Gingival Fibromatosis and Its Impact on Dental Treatment
2019
Introduction: Gingival Fibromatosis orGingival Hyperplasia is a rare disorderwith slow and progressive growth andis characterized by being a neoplasm inthe gingival tissue, where it can be foundin a localized manner. This study aimsto elucidate the characteristics and possiblemanifestations, aiming to facilitateits identifi cation, treatment and control.Methodology: This is a literature review.Forty-two articles and theses with languagesin English, Spanish, French, and Portuguesewere researched, whose sourcesare Scielo and Pubmed, and 25 articleswere included for their relevance to thetopic. Literature review: Gingival fi bromatosisis a clinical manifestation presentin several genetic syndromes that canlead to a craniofacial involvement that ischaracterized by the expansion and accumulationof connective tissue with increasednumber of cells and collagen fi bers.Fibromatosis has a proliferation of well-differentiated fi broblasts with varying amountsof collagen between proliferating c...
Traumatic gingival fibroma of anterior maxilla: A case report
International Dental Journal of Student's Research, 2022
Traumatic fibroma, also called irritation fibroma is a common oral lesion which is benign and exophytic in appearance. It develops as result of tissue injury and can occur at any age. It is the healed end product of the inflammatory hyperplastic lesion. Sites most commonly involved are buccal mucosa, any soft tissue site, tongue, gingiva. Female predilection seen. It is the most common reactive lesion, and the treatment of choice is surgical excision. The aim of this case report is to present a benign lesion in a 33 years old female patient, who reported to the department with a complaint of pain and swelling in the right upper front tooth region since 12-15 days and on examination, the lesion appeared well circumscribed, lobulated, tender, smooth, firm and reddish pink swelling measuring 2 cm × 3 cm involving right maxillary premolars. Surgical excision of the lesion was done. No recurrence was noted 1 month postoperatively. Radiographic and histopathological examination is essenti...
Idiopathic Gingival Fibromatosis - a Case Series
International Journal of Advanced Research, 2020
Unusual Cases with the complaint of swollen gums in the region of left upper and lower back teeth since 2years of are presented. They had moderate to severe, unilateral diffuse gingival enlargement in the maxilla and mandible. The diagnosis was made based on clinical and histopathological examination after ruling out drug and family history. Surgical removal of the hyperplastic tissue was done.