in protein processing and trafficking (original) (raw)

Role of the NH2-terminal Membrane Spanning Domain of Multidrug Resistance Protein 1/ABCC1 in Protein Processing and Trafficking

Christopher Westlake

Molecular Biology of the Cell, 2005

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Portrait of multifaceted transporter, the multidrug resistance-associated protein 1 (MRP1/ABCC1)

László Homolya

Pflügers Archiv - European Journal of Physiology, 2007

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Charged Amino Acids in the Sixth Transmembrane Helix of Multidrug Resistance Protein 1 (MRP1/ABCC1) Are Critical Determinants of Transport Activity

Roger Deeley

Journal of Biological Chemistry, 2002

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Identification of Proline Residues in the Core Cytoplasmic and Transmembrane Regions of Multidrug Resistance Protein 1 (MRP1/ABCC1) Important for Transport Function, Substrate Specificity, and Nucleotide Interactions

Roger Deeley

Journal of Biological Chemistry, 2004

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Functional Reconstitution of Substrate Transport by Purified Multidrug Resistance Protein MRP1 (ABCC1) in Phospholipid Vesicles

Roger Deeley

Journal of Biological Chemistry, 2000

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Mutations of Charged Amino Acids in or near the Transmembrane Helices of the Second Membrane Spanning Domain Differentially Affect the Substrate Specificity and Transport Activity of the Multidrug Resistance Protein MRP1 (ABCC1)

Roger Deeley

Molecular Pharmacology, 2004

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Membrane topology of the human multidrug resistance-associated protein (MRP) and its homologs

Gábor Tusnády, Balazs Sarkadi

Cytotechnology, 1998

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Mutational Analysis of Ionizable Residues Proximal to the Cytoplasmic Interface of Membrane Spanning Domain 3 of the Multidrug Resistance Protein, MRP1 (ABCC1)

Roger Deeley

Journal of Biological Chemistry, 2004

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Functional Importance of Three Basic Residues Clustered at the Cytosolic Interface of Transmembrane Helix 15 in the Multidrug and Organic Anion Transporter MRP1 (ABCC1)

Roger Deeley

Journal of Biological Chemistry, 2005

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The Structure of the Multidrug Resistance Protein 1 (MRP1/ABCC1)

Roger Deeley

Journal of Biological Chemistry, 2001

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Multidrug resistance protein 4 (MRP4/ABCC4): a versatile efflux transporter for drugs and signalling molecules

Rosalinde Masereeuw

Trends in Pharmacological Sciences, 2008

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Functional Multidrug Resistance Protein (MRP1) Lacking the N-terminal Transmembrane Domain

Gábor Tusnády, Balazs Sarkadi

Journal of Biological Chemistry, 1998

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Membrane Topology of the Multidrug Resistance Protein (MRP)

Roger Deeley

Journal of Biological Chemistry, 1997

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Molecular Modeling Correctly Predicts the Functional Importance of Phe594 in Transmembrane Helix 11 of the Multidrug Resistance Protein, MRP1 (ABCC1)

Roger Deeley

Journal of Biological Chemistry, 2003

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Role of the MRP1/ABCC1 Multidrug Transporter Protein in Cancer

Murray Norris

IUBMB Life, 2007

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Mouse transporter protein, a membrane protein that regulates cellular multidrug resistance, is localized to lysosomes

Tom Hobman

Cancer research, 1999

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Substrate recognition and transport by multidrug resistance protein 1 (ABCC1)

Roger Deeley

FEBS Letters, 2005

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STRUCTURE AND FUNCTION OF MULTIDRUG TRANSPORTER PROTEINS AND MECHANISM OF RESISTANCE TO AVAILABLE CHEMOTHERAPY

IJAR Indexing

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Identification and Characterization of Functionally Important Elements in the Multidrug Resistance Protein 1 COOH-terminal Region

Roger Deeley

Journal of Biological Chemistry, 2004

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Identification of Domains Participating in the Substrate Specificity and Subcellular Localization of the Multidrug Resistance Proteins MRP1 and MRP2

Takeshi Uchiumi

Journal of Biological Chemistry, 2003

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Localization, Regulation, and Substrate Transport Properties of Bpt1p, a Saccharomyces cerevisiae MRP-Type ABC Transporter

Anand K Bachhawat

Eukaryotic Cell, 2002

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Mutation of proline residues in the NH2-terminal region of the multidrug resistance protein, MRP1 (ABCC1): effects on protein expression, membrane localization, and transport function

Roger Deeley

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003

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Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters

Roger Deeley

Toxicology, 2001

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Multiple Membrane-associated Tryptophan Residues Contribute to the Transport Activity and Substrate Specificity of the Human Multidrug Resistance Protein, MRP1

Roger Deeley

Journal of Biological Chemistry, 2002

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Multidrug resistance mediated by the ATP‐binding cassette transporter protein MRP

Roger Deeley

BioEssays, 1998

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Monoclonal Antibodies That Inhibit the Transport Function of the 190-kDa Multidrug Resistance Protein, MRP

Roger Deeley

Journal of Biological Chemistry, 1999

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Functional Expression of Multidrug Resistance Protein 4 MRP4/ABCC4

Roslyn M Bill

2019

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Mammalian multidrug-resistance proteins (MRPs)

Andrew Slot

Essays in Biochemistry, 2011

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The predicted transmembrane fragment 17 of the human multidrug resistance protein 1 (MRP1) behaves as an interfacial helix in membrane mimics

Nadège Jamin

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2007

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Structural Characterization of the Drug Translocation Path of MRP1/ABCC1

Yossi Tsfadia

Israel Journal of Chemistry, 2014

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Mutation of a Single Conserved Tryptophan in Multidrug Resistance Protein 1 (MRP1/ABCC1) Results in Loss of Drug Resistance and Selective Loss of Organic Anion Transport

Roger Deeley

Journal of Biological Chemistry, 2001

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Mapping of the MRPm5 epitope to the cytosolic region between transmembrane helices 13 and 14 in the drug and organic anion transporter, MRP1 (ABCC1)

Roger Deeley

Biochemical and Biophysical Research Communications, 2004

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Transmembrane Helix 11 of Multidrug Resistance Protein 1 (MRP1/ABCC1): Identification of Polar Amino Acids Important for Substrate Specificity and Binding of ATP at Nucleotide Binding Domain 1

Roger Deeley

Biochemistry, 2004

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Structural Determinants of Substrate Specificity Differences between Human Multidrug Resistance Protein (MRP) 1 (ABCC1) and MRP3 (ABCC3)

Roger Deeley

Drug Metabolism and Disposition, 2008

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Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1)

Balazs Sarkadi

Journal of Cell Science, 2000

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