Are androgen receptor variants a substitute for the full-length receptor? (original) (raw)
Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor
Charles Sawyers
Proceedings of the National Academy of Sciences, 2010
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A Novel Androgen Receptor Splice Variant Is Up-regulated during Prostate Cancer Progression and Promotes Androgen Depletion-Resistant Growth
Jonathan Melamed
Cancer Research, 2009
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Androgen receptor splice variants activating the full-length receptor in mediating resistance to androgen-directed therapy
Yanfeng Qi
Oncotarget, 2014
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The Androgen Receptor in Prostate Cancer: Effect of Structure, Ligands and Spliced Variants on Therapy
Maria Mudryj
Biomedicines
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Splice variants of androgen receptor and prostate cancer
Orazio Caffo
Oncology Reviews, 2016
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Data of relative mRNA and protein abundances of androgen receptor splice variants in castration-resistant prostate cancer
Derek Zhang
Data in Brief, 2021
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Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer
Daniel Nava Rodrigues
The Journal of clinical investigation, 2018
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Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
Ilsa Coleman
Journal of Clinical Investigation, 2010
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Comprehensive Profiling of the Androgen Receptor in Liquid Biopsies from Castration-resistant Prostate Cancer Reveals Novel Intra-AR Structural Variation and Splice Variant Expression Patterns
Luc Dirix
European Urology, 2017
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Splicing variants of androgen receptor in prostate cancer
Yanfeng Qi
American journal of clinical and experimental urology, 2013
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Androgen Receptor Cofactors in Prostate Cancer: Potential Therapeutic Targets of Castration-Resistant Prostate Cancer
Akira Yokomizo
Current Cancer Drug Targets, 2011
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Androgen Receptor Splice Variants Activate Androgen Receptor Target Genes and Support Aberrant Prostate Cancer Cell Growth Independent of Canonical Androgen Receptor Nuclear Localization Signal
Yingming Li
Journal of Biological Chemistry, 2012
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960 ASC-J9® Suppresses Castration-Resistant Prostate Cancer Growth via Degradation of Full-Length and Splice Variant Androgen Receptors
Tatsuo Tochigi
The Journal of Urology, 2012
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Androgen receptor splice variants dimerize to transactivate target genes
Yanfeng Qi
Cancer research, 2015
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Androgen receptor splice variant 7 (AR-V7) and drug efficacy in castration-resistant prostate cancer: biomarker for treatment selection exclusion or inclusion?
William Figg
Cancer biology & therapy, 2016
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Assessment of Androgen Receptor splice variant-7 as a biomarker of clinical response in castration-sensitive prostate cancer
Bora Gurel
2022
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Prospective Multicenter Validation of Androgen Receptor Splice Variant 7 and Hormone Therapy Resistance in High-Risk Castration-Resistant Prostate Cancer: The PROPHECY Study
Gabor Kemeny
Journal of Clinical Oncology
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AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression
Betsy Hirsch
Oncogene, 2012
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Beyond Prostate Cancer: An Androgen Receptor Splice Variant Expression in Multiple Malignancies, Non-Cancer Pathologies, and Development
Maria Mudryj
Biomedicines
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Analytical Validation and Clinical Qualification of a New Immunohistochemical Assay for Androgen Receptor Splice Variant-7 Protein Expression in Metastatic Castration-resistant Prostate Cancer
Daniel Nava Rodrigues
European urology, 2016
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Lessons from tissue compartment-specific analysis of androgen receptor alterations in prostate cancer
Mark Daniel
The Journal of steroid biochemistry and molecular biology, 2016
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Targeting a Single Alternative Polyadenylation Site Coordinately Blocks Expression of Androgen Receptor mRNA Splice Variants in Prostate Cancer
Yingming Li
Cancer Research
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Androgen receptor splice variants mediate enzalutamide resistance in castration-resistant prostate cancer cell lines
Yingming Li
2013
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Treatment-Dependent Androgen Receptor Mutations in Prostate Cancer Exploit Multiple Mechanisms to Evade Therapy
Kenneth Pienta
Cancer Research, 2009
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Small molecule screening reveals a transcription-independent pro-survival function of androgen receptor in castration-resistant prostate cancer
Inna Shyshynova
Cell Cycle, 2009
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Development of an Androgen Receptor Inhibitor Targeting the N-Terminal Domain of Androgen Receptor for Treatment of Castration Resistant Prostate Cancer
Hisham Mohammed
Cancers, 2021
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Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer
James Dalton
Cancer research, 2017
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Increased androgen receptor transcription: a cause of castration-resistant prostate cancer and a possible therapeutic target
Masaki Shiota
Journal of Molecular …, 2011
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Androgen receptor splice variants contribute to prostate cancer aggressiveness through induction of EMT and expression of stem cell marker genes
Wael Sakr
The Prostate, 2015
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Clinical relevance of androgen receptor alterations in prostate cancer
Pernilla Wikström
Endocrine Connections, 2017
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Recent Discoveries in the Androgen Receptor Pathway in Castration-Resistant Prostate Cancer
Asish Pati
Frontiers in Oncology, 2020
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Androgen Receptor Signaling Pathway in Prostate Cancer: From Genetics to Clinical Applications
Alessia Cimadamore
Cells
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Expression of Androgen Receptor Splice Variants in Prostate Cancer Bone Metastases is Associated with Castration-Resistance and Short Survival
Anders Bergh
PLoS ONE, 2011
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