Heterocyclic cycloalkanol ethylamines as norepinephrine reuptake inhibitors (original) (raw)
Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI)
Warren Wade
Bioorganic & Medicinal Chemistry Letters, 2008
View PDFchevron_right
3-(Arylamino)-3-phenylpropan-2-olamines as a new series of dual norepinephrine and serotonin reuptake inhibitors
Paige Mahaney
Bioorganic & Medicinal Chemistry Letters, 2009
View PDFchevron_right
Discovery of N-methyl-1-(1-phenylcyclohexyl)ethanamine, a novel triple serotonin, norepinephrine and dopamine reuptake inhibitor
Kerry Spear
Bioorganic & Medicinal Chemistry Letters, 2011
View PDFchevron_right
Structure–activity relationships of chiral selective norepinephrine reuptake inhibitors (sNRI) with increased oxidative stability
Anna Aparicio, Warren Wade
Bioorganic & Medicinal Chemistry Letters, 2008
View PDFchevron_right
Design and optimization of selective serotonin re-uptake inhibitors with high synthetic accessibility Part 1
Mark Lansdell
Bioorganic & Medicinal Chemistry Letters, 2009
View PDFchevron_right
Synthesis and activity of a new class of dual acting norepinephrine and serotonin reuptake inhibitors: 3-(1H-indol-1-yl)-3-arylpropan-1-amines
Paige Mahaney
Bioorganic & Medicinal Chemistry, 2006
View PDFchevron_right
Designing rapid onset selective serotonin re-uptake inhibitors. Part 1: Structure–activity relationships of substituted (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthaleneamine
Barry Jones
Bioorganic & Medicinal Chemistry Letters, 2006
View PDFchevron_right
Synthesis and activity of novel 1- or 3-(3-amino-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones as selective norepinephrine reuptake inhibitors
an vu
Bioorganic & Medicinal Chemistry Letters, 2008
View PDFchevron_right
Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor
Kerry Spear
Bioorganic & Medicinal Chemistry Letters, 2011
View PDFchevron_right
Discovery and structure–activity relationships of novel selective norepinephrine and dual serotonin/norepinephrine reuptake inhibitors
Christian Montalbetti
Bioorganic & Medicinal Chemistry Letters, 2005
View PDFchevron_right
Synthesis of a potent wide-spectrum serotonin-, norepinephrine-, dopamine-reuptake inhibitor (SNDRI) and a species-selective dopamine-reuptake inhibitor based on the gamma-amino alcohol functional group
Elliott Richelson
Bioorganic & Medicinal Chemistry Letters, 1998
View PDFchevron_right
Discovery of a Potent, Dual Serotonin and Norepinephrine Reuptake Inhibitor
Magnus W Walter
ACS Medicinal Chemistry Letters, 2013
View PDFchevron_right
Pharmacological and Behavioral Analysis of the Effects of Some Bivalent Ligand-Based Monoamine Reuptake Inhibitors
alan kozikowski
Journal of Medicinal Chemistry, 2001
View PDFchevron_right
Designing rapid onset selective serotonin re-uptake inhibitors. 2: Structure–activity relationships of substituted (aryl)benzylamines
Paul Morgan
Bioorganic Medicinal Chemistry Letters, 2008
View PDFchevron_right
Structure–activity relationships of the 1-amino-3-(1H-indol-1-yl)-3-phenylpropan-2-ol series of monoamine reuptake inhibitors
Paige Mahaney
Bioorganic & Medicinal Chemistry Letters, 2009
View PDFchevron_right
Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition
Thomas Ryckmans
Bioorganic & Medicinal Chemistry Letters, 2008
View PDFchevron_right
Structural Requirements for Modulating 4-Benzylpiperidine Carboxamides from Serotonin/Norepinephrine Reuptake Inhibitors to Triple Reuptake Inhibitors
Eunae Kim
Biomolecules & Therapeutics, 2021
View PDFchevron_right
3β-(4-Ethyl-3-iodophenyl)nortropane-2β- carboxylic Acid Methyl Ester as a High-Affinity Selective Ligand for the Serotonin Transporter
Anita Lewin
Journal of Medicinal Chemistry, 1997
View PDFchevron_right
Novel 3,3-disubstituted pyrrolidines as selective triple serotonin/norepinephrine/dopamine reuptake inhibitors
Matthew Lucas
Bioorganic & Medicinal Chemistry Letters, 2008
View PDFchevron_right
Elucidation of Structural Elements for Selectivity across Monoamine Transporters: Novel 2-[(Diphenylmethyl)sulfinyl]acetamide (Modafinil) Analogues
Theresa Kopajtic, Jonathan Katz
Journal of Medicinal Chemistry, 2014
View PDFchevron_right
Stereospecific inhibition of monoamine uptake transporters by meta-hydroxyephedrine isomers.
Nicholas V Cozzi, Ph.D., Marcian Van Dort, Arnold Ruoho
Journal of Neural Transmission, 2002
View PDFchevron_right
Discovery of a new series of monoamine reuptake inhibitors, the 1-amino-3-(1 H-indol-1-yl)-3-phenylpropan-2-ols
Eric Manas
Bioorganic & Medicinal Chemistry Letters, 2009
View PDFchevron_right
Structure−Activity Relationship Studies of 4-[2-(Diphenylmethoxy)ethyl]-1-benzylpiperidine Derivatives and Their N-Analogues: Evaluation of Behavioral Activity of O- and N-Analogues and Their Binding to Monoamine Transporters
aloke dutta
Journal of Medicinal Chemistry, 2001
View PDFchevron_right
Second generation N-(1,2-diphenylethyl)piperazines as dual serotonin and noradrenaline reuptake inhibitors: Improving metabolic stability and reducing ion channel activity
Gerwyn Bish
Bioorganic & Medicinal Chemistry Letters, 2010
View PDFchevron_right
Derivatives of (3S)-N-(biphenyl-2-ylmethyl)pyrrolidin-3-amine as selective noradrenaline reuptake inhibitors: Reducing P-gp mediated efflux by modulation of H-bond acceptor capacity
Thomas Ryckmans
Bioorganic & Medicinal Chemistry Letters, 2008
View PDFchevron_right
Studies towards the next generation of antidepressants. Part 1: indolylcyclohexylamines as potent serotonin reuptake inhibitors
Richard Mewshaw
Bioorganic & Medicinal Chemistry Letters, 2001
View PDFchevron_right
Studies of the Biogenic Amine Transporters. 12. Identification of Novel Partial Inhibitors of Amphetamine-Induced Dopamine Release
Joseph Pariser
Journal of Pharmacology and Experimental Therapeutics, 2008
View PDFchevron_right
Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs)
Thaddeus Molski
Bioorganic & Medicinal Chemistry Letters, 2005
View PDFchevron_right
Faculty of 1000 evaluation for Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET
George White
F1000 - Post-publication peer review of the biomedical literature, 2011
View PDFchevron_right