The ontogeny of drug metabolizing enzymes and transporters in the rat (original) (raw)

The postnatal development of drug-metabolizing enzymes in hepatic, pulmonary and renal tissues of the goat

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Journal of Veterinary Pharmacology and Therapeutics, 1993

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Presence of phase I and phase II drug metabolizing enzymes in cultured human foetal hepatocytes

André Guillouzo

Biochemical Pharmacology, 1982

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Carlo Nebbia

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Expression and induction of drug-metabolizing enzymes in cultured fetal rat hepatocytes

Nadine Stouvenakers

Cell Biology and Toxicology, 1994

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British Journal of Clinical Pharmacology, 2003

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Timing and Duration of Drug Exposure Affects Outcomes of a Drug-Nutrient Interaction During Ontogeny

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Pharmaceutics, 2010

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Genetic Aspects of Toxicity during Development

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Environmental Health Perspectives, 1976

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Acta Physiologica Hungarica, 2013

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Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54

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Estimating Pediatric Doses of Drugs Metabolized by Cytochrome P450 (CYP) Isozymes, Based on Physiological Liver Development and Serum Protein Levels

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YAKUGAKU ZASSHI, 2010

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Expression Profiles of Metabolic Enzymes and Drug Transporters in the Liver and along the Intestine of Beagle Dogs

Neil Parrott

Drug Metabolism and Disposition, 2012

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Metabolism: A Bottleneck in In Vitro Toxicological Test Development The Report and Recommendations of ECVAM Workshop 541

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Determinants of Drug Metabolism in Early Neonatal Life

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Current Clinical Pharmacology, 2007

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Differential effects of microsomal enzyme–inducing chemicals on the hepatic expression of rat organic anion transporters, OATP1 and OATP2

Dylan Hartley

Hepatology, 2001

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Evaluation of the Assumptions of an Ontogeny Model of Rat Hepatic Cytochrome P450 Activity

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Drug Metabolism and Disposition, 2007

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Drug metabolizing enzyme activities in rat liver epithelial cell lines, hepatocytes and bile duct cells

Mohamed Elmouelhi

Biochemical Pharmacology, 1991

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Ontogeny of hepatic drug transporters as quantified by LC-MS/MS proteomics

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Clinical pharmacology and therapeutics, 2016

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A retrospective analysis of developmental toxicity studies in rat and rabbit: What is the added value of the rabbit as an additional test species?

Theo Vermeire

Regulatory Toxicology and Pharmacology, 2008

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Human ontogeny of drug transporters: Review and recommendations of the pediatric transporter working group

Michael Rieder

Clinical pharmacology and therapeutics, 2015

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Drug-Metabolizing Enzymes Mechanisms and Functions

Salah Sheweita

Current Drug Metabolism, 2000

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Species-specific developmental toxicity in rats and rabbits: Generation of a reference compound list for development of alternative testing approaches

Alexander Amberg

Reproductive Toxicology, 2018

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Proposal for a tiered approach to developmental toxicity testing for veterinary pharmaceutical products for food-producing animals

Gregg Cappon

Food and Chemical Toxicology, 2003

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Changes of Drug Metabolizing Enzymes in the Liver of Male Sheep Exposed to either Cypermethrin or Dimethoate

Salah Sheweita

Drug Metabolism Letters, 2012

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