Thymus, central T cell self-tolerance and type 1 diabetes
Vincent Geenen
International Diabetes Monitor, 2002
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Self-antigen–presenting cells expressing diabetes-associated autoantigens exist in both thymus and peripheral lymphoid organs
david garza
Journal of Clinical Investigation, 2001
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Dynamics of Pathogenic and Suppressor T Cells in Autoimmune Diabetes Development
Nadia Giarratana, Luciano Adorini
The Journal of Immunology, 2003
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The Thymus Contains a High Frequency of Cells that Prevent Autoimmune Diabetes on Transfer into Prediabetic Recipients
Abdelhadi Saoudi
Journal of Experimental Medicine, 1996
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Through Regulation of TCR Expression Levels, an Idd7 Region Gene(s) Interactively Contributes to the Impaired Thymic Deletion of Autoreactive Diabetogenic CD8+ T Cells in Nonobese Diabetic Mice
Aaron Brown
The Journal of Immunology, 2008
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Thymus-specific deletion of insulin induces autoimmune diabetes
Yong Fan
The EMBO Journal, 2009
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T cell-mediated inhibition of the transfer of autoimmune diabetes in NOD mice
Mireille Dardenne
Journal of Experimental Medicine, 1989
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The thymus in 2013: from a 'vestigial' organ to immunological self-tolerance and autoimmunity
Vincent Geenen
Proceedings of the Belgian Royal Academies of Medicine, 2014
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Thymic T cell anergy in autoimmune nonobese diabetic mice is mediated by deficient T cell receptor regulation of the pathway of p21ras activation
Alan Lazarus
Journal of Experimental Medicine
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Diabetic Mice Tolerance to Islet ß Cells of Nonobese Overcoming a Checkpoint in T Cell by B Lymphocytes Is Critical in -Mediated Antigen Presentation g7 IA
Susan Rostami
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Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance
Ryutaro Hirose
International Immunology, 1997
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Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reaction
Eugenio Marin
Proceedings of the …, 1998
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Abnormal T-Cell Development in the Thymus of Non-obese Diabetic Mice: Possible Relationship With the Pathogenesis of Type 1 Autoimmune Diabetes
Julia Lemos
Frontiers in Endocrinology, 2018
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Mouse Tolerance" in the Nonobese Diabetic Expressing L-Selectin Mediate "Active TCR{alpha}{beta}+CD4+ Thymocytes Mature Mainstream
Jean-Marc Gombert
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Peripheral Antigens Mechanisms in Tolerance Toward Suggests a Role for Central Self-Antigens in Human Thymus Transcription of a Broad Range of
Xavier Ferrer-Francesch
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Cutting Edge: Thymic Positive Selection and Peripheral Activation of Islet Antigen-Specific T Cells: Separation of Two Diabetogenic Steps by an I-Ag7 Class II MHC ß- …
Osami Kanagawa
The Journal of …, 1998
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Following the Fate of One Insulin-Reactive CD4 T cell: Conversion Into Teffs and Tregs in the Periphery Controls Diabetes in NOD Mice
Philippe Pagni, Georgia Fousteri, Amy Dave, Florence Lambolez
Diabetes, 2012
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Abnormal T cell selection on nod thymic epithelium is sufficient to induce autoimmune manifestations in C57BL/6 athymic nude mice
Véronique Thomas-Vaslin
Proceedings of the National Academy of Sciences, 1997
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Transcription of a broad range of self-antigens in human thymus suggests a role for central mechanisms in tolerance toward peripheral antigens.
Ricardo Pujol-Borrell
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Maintaining or breaking CD8+ T-cell tolerance to β islet cell antigens: lessons from transgenic mouse models
Eliane Piaggio
Journal of Autoimmunity, 2004
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Bim deficiency protects NOD mice from diabetes by diverting thymocytes to regulatory T cells
Andreas Strasser
Diabetes, 2015
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Regulation of NOD mouse autoimmune diabetes by T cells that recognize a TCR CDR3 peptide
Dana Elias
International Immunology, 1999
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Faculty of 1000 evaluation for Following the Fate of One Insulin-Reactive CD4 T cell: Conversion Into Teffs and Tregs in the Periphery Controls Diabetes in NOD Mice
Scott Lieberman
F1000 - Post-publication peer review of the biomedical literature, 2012
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T-Cell Tolerance by Dendritic Cells and Macrophages as a Mechanism for the Major Histocompatibility Complex-Linked Resistance to Autoimmune Diabetes
P. Santamaria
Diabetes, 2002
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In a Transgenic Model of Spontaneous Autoimmune Diabetes, Expression of a Protective Class II MHC Molecule Results in Thymic Deletion of Diabetogenic CD8+ T Cells
Shawn Hartman
The Journal of Immunology, 2004
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Cutting Edge: Thymic Positive Selection and Peripheral Activation of Islet Antigen-Specific T Cells: Separation of Two Diabetogenic Steps by an I-Ag7 Class II MHC β-Chain Mutant
Osami Kanagawa
Journal of Immunology, 1998
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Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes
ansu (ansuman) satpathy
Proceedings of The National Academy of Sciences, 2007
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Low rate of proliferation in immature thymocytes of the non-obese diabetic mouse maps to the Idd6 diabetes susceptibility region
Carlos Penha-gonçalves
Diabetologia, 2001
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Responses against islet antigens in NOD mice are prevented by tolerance to proinsulin but not IGRP
Anthony Purcell
Journal of Clinical Investigation, 2006
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Transgenic Mice Nonobese Diabetic 8.3 TCR IGRP Is Required for Diabetes in Autoimmunity to Both Proinsulin and
lina mariana
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