Structure–function relationships in the hammerhead ribozyme probed by base rescue (original) (raw)

Faculty of 1000 evaluation for Capturing hammerhead ribozyme structures in action by modulating general base catalysis

Pascale Legault

F1000 - Post-publication peer review of the biomedical literature, 2008

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Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis

Young-In Chi

PLoS Biology, 2008

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Structural Variation Induced by Different Nucleotides at the Cleavage Site of the Hammerhead Ribozyme †

Nassim Usman

Biochemistry, 1998

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Structure—function studies of the hammerhead ribozyme

Sandeep Verma

Current Opinion in Chemical Biology, 1997

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Morphing the minimal and full-length hammerhead ribozymes: implications for the cleavage mechanism

NOE PENA

Biological Chemistry, 2007

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Computational Mutagenesis Studies of Hammerhead Ribozyme Catalysis

Tai-sung Lee

Journal of the American Chemical Society, 2010

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A small modified hammerhead ribozyme and its conformational characteristics determined by mutagenesis and lattice calculation

Brooke Lustig

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Rescue of abasic hammerhead ribozymes by exogenous addition of specific bases

Leonid Beigelman, Alessio Peracchi

Proceedings of the National Academy of Sciences, 1996

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Using linkers to investigate the spatial separation of the conserved nucleotides A9 and G12 in the hammerhead ribozyme

mohammad reza r. Moghaddam

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1994

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A Kinetic and Thermodynamic Framework for the Hammerhead Ribozyme Reaction

Klemens Hertel

Biochemistry, 1994

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Thermodynamic Dissection of the Substrate−Ribozyme Interaction in the Hammerhead Ribozyme †

Klemens Hertel

Biochemistry, 1998

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Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme

Timothy D Wilson

Proceedings of the National Academy of Sciences, 2010

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Specificity of hammerhead ribozyme cleavage

Klemens Hertel

The EMBO Journal, 1996

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The Structural Basis of Hammerhead Ribozyme Self-Cleavage

Alexander Karpeisky

Cell, 1998

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Physicochemical Characterization of the Catalytic Unit of Hammerhead Ribozyme and Its Relationship with the Catalytic Activity

Chojiro Kojima

Biophysica

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Nucleobase catalysis in the hairpin ribozyme

Timothy D Wilson

RNA (New York, N.Y.), 2006

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Origin of Mutational Effects at the C3 and G8 Positions on Hammerhead Ribozyme Catalysis from Molecular Dynamics Simulations

Tai-sung Lee

Journal of the American Chemical Society, 2008

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Mixed DNA/RNA polymers are cleaved by the hammerhead ribozyme

Nassim Usman

Biochemistry, 1990

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Involvement of a Specific Metal Ion in the Transition of the Hammerhead Ribozyme to Its Catalytic Conformation

Leonid Beigelman, Alessio Peracchi

Journal of Biological Chemistry, 1997

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Model for General Acid−Base Catalysis by the Hammerhead Ribozyme: pH−Activity Relationships of G8 and G12 Variants at the Putative Active Site †

John Burke

Biochemistry, 2005

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Sequence specificity of the hammerhead ribozyme revisited; the NHH rule

Narendra Vaish

Nucleic Acids Research, 1998

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Active-Site Monovalent Cations Revealed in a 1.55-Å-Resolution Hammerhead Ribozyme Structure

Harrison Anderson

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Base and Sugar Requirements for RNA Cleavage of Essential Nucleoside Residues in Internal Loop B of the Hairpin Ribozyme: Implications for Secondary Structure

Leonid Beigelman

Nucleic Acids Research, 1996

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A stable hammerhead structure is not required for endonucleolytic activity of a ribozyme in vivo

Gerhard Steger

Gene, 1994

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Solvent Protection of the Hammerhead Ribozyme in the Ground State: Evidence for a Cation-Assisted Conformational Change Leading to Catalysis †

John Burke

Biochemistry, 2003

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In vitro evolution of the hammerhead ribozyme to a purine-specific ribozyme using mutagenic PCR with two nucleotide analogues1

Narendra Vaish

Journal of Molecular Biology, 2000

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In vitro evolution of the hammerhead ribozyme to a purine-specific ribozyme using mutagenic PCR with two nucleotide analogues

Narendra Vaish

Journal of Molecular Biology, 2000

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Influence of substrate structure on cleavage by hammerhead ribozyme

Daniela Scarabino

FEBS Letters, 1996

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