Targeting gastrin-releasing peptide receptors for cancer treatment (original) (raw)

Gastrin-releasing peptide receptor as a molecular target in experimental anticancer therapy

Fabricia Petronilho

Annals of Oncology, 2007

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Targeting the Gastrin-Releasing Peptide Receptor (GRP-R) in Cancer Therapy: Development of Bombesin-Based Peptide–Drug Conjugates

Rita Olah-Szabo

International Journal of Molecular Sciences, 2023

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Phase I and Imaging Trial of a Monoclonal Antibody Directed Against Gastrin-Releasing Peptide In Patients With Lung Cancer

James Mulshine

Clinical Cancer …, 1999

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Selective stimulation of small cell lung cancer clonal growth by bombesin and gastrin-releasing peptide

Frank Cuttitta

Regulatory Peptides, 1987

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Gastrin releasing peptide-preferring bombesin receptors mediate growth of human renal cell carcinoma

Jean-louis Boulay, Elizaveta Fasler-kan

Journal of the …, 2000

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Characterization of a bombesin/gastrin‐releasing peptide receptor on a human gastric‐cancer cell line

Shaun Preston

… journal of cancer, 1994

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Isolation of the bombesin/gastrin-releasing peptide receptor from human small cell lung carcinoma NCI-H345 cells

Lynda Brown Portanova

Journal of Biological Chemistry, 1991

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I. High affinity receptors for bombesin/GRP-like peptides on human small cell lung cancer

Frank Cuttitta

Life Sciences, 1985

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Gastrin-Releasing Peptide (GRP) Analogues for Cancer Imaging

Penelope Bouziotis

Cancer Biotherapy and Radiopharmaceuticals, 2004

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Gastrin-releasing peptide: in vivo and in vitro growth effects on an acinar pancreatic carcinoma

Amor Hajri

Cancer research, 1992

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ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth

Terry Moody

Peptides, 2014

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Inhibition of growth of MKN45 human gastric-carcinoma xenografts in nude mice by treatment with bombesin/gastrin-releasing-peptide antagonist (RC-3095) and somatostatin analogue RC-160

G. Halmos

International Journal of Cancer, 1994

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Increased gastrin-releasing peptide (GRP) receptor expression in tumour cells confers sensitivity to [Arg6,D-Trp7,9,NmePhe8]-substance P (6-11)-induced growth inhibition

Uzma Hanif

British journal of cancer, 2003

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High-affinity binding sites for gastrin-releasing peptide on human colorectal cancer …

Shaun Preston

British journal of …

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Pre-clinical evaluation of eight DOTA coupled gastrin-releasing peptide receptor (GRP-R) ligands for in vivo targeting of receptor-expressing tumors

Michela Aurilio

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Expression of the gastrin-releasing peptide receptor confers a growth response to bombesin in immortalized human bronchial epithelial cells

Ala-Eddin Al Moustafa

Cancer research, 1995

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Bombesin antagonists inhibit in vitro and in vivo growth of human gastric cancer and binding of bombesin to its receptors

Tibor Ertl

Journal of Cancer Research and Clinical Oncology, 1994

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Gastrin-releasing peptide (GRP) induces angiogenesis and the specific GRP blocker 77427 inhibits tumor growth in vitro and in vivo

Miguel Terry

Oncogene, 2005

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Antitumoral activity of bombesin analogues on small cell lung cancer xenografts: Relationship with bombesin receptor expression

François Thomas

Lung Cancer, 1993

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Characterization of Bombesin/Gastrin-releasing Peptide Receptors in Human Breast Cancer and Their Relationship to Steroid Receptor Expression

James Wittliff

Cancer Research, 1995

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In Vitro and in Vivo Characterization of Novel 18 F-Labeled Bombesin Analogues for Targeting GRPR-Positive Tumors

Miljen Martic, Keith Graham

Bioconjugate Chemistry, 2010

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In vitro and in vivo evaluation of a 64Cu-labeled NOTA-Bn-SCN-Aoc-bombesin analogue in gastrin-releasing peptide receptor expressing prostate cancer

Buck Rogers

Nuclear Medicine and Biology, 2012

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Combination of gastrin-releasing peptide antagonist with cytotoxic agents produces synergistic inhibition of growth of human experimental colon cancers

Roberto Perez

Cell …, 2012

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18F-Labeled Bombesin Analog for Specific and Effective Targeting of Prostate Tumors Expressing Gastrin-Releasing Peptide Receptors

Miljen Martic, Keith Graham

Journal of Nuclear Medicine, 2011

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[Psi 13,14] bombesin analogues inhibit growth of small cell lung cancerin vitro and in vivo

Frank Cuttitta, James Mulshine

Cancer research, 1991

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Bombesin Receptor Antagonists May Be Preferable to Agonists for Tumor Targeting

D. Charalambidis, Theodosia Maina

Journal of Nuclear Medicine, 2008

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Bombesin analogues for gastrin-releasing peptide receptor imaging

Prasant Kumar Nanda

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BW2258U89: A GRP receptor antagonist which inhibits small cell lung cancer growth

Farah Zia

Life Sciences, 1995

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