Hypothalamic Regulatory Pathways and Potential Obesity Treatment Targets (original) (raw)

Dissecting the role of cocaine- and amphetamine-regulated transcript (CART) in the control of appetite

Kevin Murphy

Briefings in Functional Genomics and Proteomics, 2005

View PDFchevron_right

Actions of cocaine- and amphetamine-regulated transcript (CART) peptide on regulation of appetite and hypothalamo–pituitary axes in vitro and in vivo in male rats

Richard Hunter

Brain Research, 2001

View PDFchevron_right

The hypothalamus and obesity

Joanne Harrold, J. Halford

Recent patents on CNS drug discovery, 2006

View PDFchevron_right

Energy balance effects of central melanocortin, cocaine and amphetamine related transcript and leptin: Moving outside of the hypothalamic box

Karolina Skibicka

2009

View PDFchevron_right

Hypothalamic cocaine-and amphetamine-regulated transcript peptide is reduced and fails to modulate feeding behavior in rats with chemically-induced mammary …

SWATI KOTWAL

Pharmacology …, 2010

View PDFchevron_right

Chronic central infusion of cocaine- and amphetamine-regulated transcript (CART 55-102): effects on body weight homeostasis in lean and high-fat-fed obese rats

Michael Statnick

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2002

View PDFchevron_right

Synergistic effect of CART (cocaine- and amphetamine-regulated transcript) peptide and cholecystokinin on food intake regulation in lean mice

Alexander Kis

BMC Neuroscience, 2008

View PDFchevron_right

Effect of anorexinergic peptides, cholecystokinin (CCK) and cocaine and amphetamine regulated transcript (CART) peptide, on the activity of neurons in hypothalamic structures of C57Bl/6 mice involved in the food intake regulation

Alexander Kis

Peptides, 2010

View PDFchevron_right

Hypothalamic cocaine- and amphetamine-regulated transcript peptide is reduced and fails to modulate feeding behavior in rats with chemically-induced mammary carcinogenesis

Amit Taksande

Pharmacology Biochemistry and Behavior, 2010

View PDFchevron_right

Adage T, Scheurink AJW, de Boer SF, et al.: Hypothalamic, metabolic, and behavioral responses to pharmacological inhibition of CNS melanocortin signaling in rats

Tiziana Adage

The Journal of Neuroscience : The Official Journal of the Society for Neuroscience

View PDFchevron_right

CART in the regulation of appetite and energy homeostasis

Jackie Lau

Frontiers in neuroscience, 2014

View PDFchevron_right

Hypothalamic, Metabolic, and Behavioral Responses to Pharmacological Inhibition of CNS Melanocortin Signaling in Rats

Michael van Dijke

2001

View PDFchevron_right

Neurochemical regulators of food behavior for pharmacological treatment of obesity: current status and future prospects

Hasmik Harutyunyan

Future Medicinal Chemistry, 2020

View PDFchevron_right

Hypothalamic Neuropeptide Systems as Targets for Potential Anti-Obesity Drugs

Paolo Magni

Mini-Reviews in Medicinal Chemistry, 2007

View PDFchevron_right

Leptin stimulates neuropeptide Y and cocaine amphetamine-regulated transcript coexpressing neuronal activity in the dorsomedial hypothalamus in diet-induced obese mice

Melissa Kirigiti

The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013

View PDFchevron_right

Anorexigenic cocaine- and amphetamine-regulated transcript peptide intensifies fear reactions in rats

Ants Kask

Brain Research, 2000

View PDFchevron_right

Hypothalamic cocaine- and amphetamine-regulated transcript (CART) neurons: histochemical relationship to thyrotropin-releasing hormone, melanin-concentrating hormone, orexin/hypocretin and neuropeptide Y

Jackson Bittencourt

Brain Research, 1999

View PDFchevron_right

Neurobiology of overeating and obesity: The role of melanocortins and beyond

Louk Vanderschuren

European Journal of Pharmacology, 2011

View PDFchevron_right

Glucocorticoids decrease body weight and food intake and inhibit appetite regulatory peptide expression in the hypothalamus of rats

chen zhang

Experimental and therapeutic medicine, 2011

View PDFchevron_right

Hypothalamic cocaine-amphetamine regulated transcript (CART) is regulated by glucocorticoids

Mads Christensen

Brain Research, 2003

View PDFchevron_right

The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake

Niamh Cawley

Nature Medicine, 2009

View PDFchevron_right

Various Dietary Fats Differentially Change the Gene Expression of Neuropeptides Involved in Body Weight Regulation in Rats

Jacek Bartkowiak

Journal of Neuroendocrinology, 2007

View PDFchevron_right

Regulation of appetite to treat obesity

Jieru Lin

Expert Review of Clinical Pharmacology, 2011

View PDFchevron_right

Peptides that regulate food intake: appetite-inducing accumbens manipulation activates hypothalamic orexin neurons and inhibits POMC neurons

Hans-rudolf Berthoud

American journal of physiology. Regulatory, integrative and comparative physiology, 2003

View PDFchevron_right

Anti-obesity drugs and neural circuits of feeding

Louk Vanderschuren

Trends in Pharmacological Sciences, 2008

View PDFchevron_right

Overexpression of CART in the PVN Increases Food Intake and Weight Gain in Rats

Niamh Martin

Obesity, 2008

View PDFchevron_right

Blunted Vagal Cocaine- and Amphetamine-Regulated Transcript Promotes Hyperphagia and Weight Gain

Danielle Quinn

Cell Reports

View PDFchevron_right

Emerging Therapeutic Strategies for Obesity

David Cummings

Endocrine Reviews, 2006

View PDFchevron_right