TGF-β signaling, Smads, and tumor suppressors (original) (raw)

TGF-b signaling, Smads, and tumor suppressors

Richard W Padgett

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Smads Are the Central Component in Transforming Growth Factor-β Signaling

Richard W Padgett

Pharmacology & Therapeutics, 1998

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Signaling of transforming growth factor-β family members through Smad proteins

Marie-Jose Goumans

European Journal of Biochemistry, 2000

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Smad regulation in TGF-β signal transduction

Serhiy Souchelnytskyi

Journal of Cell Science, 2001

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SMAD regulation in TGF-beta signal transduction

Carl-henrik Heldin

Journal of Cell Science

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Differential regulation of TGF-β signaling through Smad2, Smad3 and Smad4

Anke Klippel

Oncogene, 2003

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Functional Characterization of Transforming Growth Factor beta Signaling in Smad2- and Smad3-deficient Fibroblasts

Raju Kucherlapati

Journal of Biological Chemistry, 2001

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Differential regulation of TGF-beta signaling through Smad2, Smad3 and Smad4

Anke Klippel

Oncogene, 2003

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Transforming growth factor-β signalling: Role and consequences of Smad linker region phosphorylation

Danielle Kamato, Terrence J Piva, Narin Osman

Cellular Signalling, 2013

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The Life Story of TGFβs superfamily: from the beginning to the end

Soheil Eagderi

International Journal of Aquatic Biology, 2020

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Smad7: not only a regulator, but also a cross-talk mediator of TGF-β signalling

Xiaohua Yan

Biochemical Journal, 2011

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Distribution of phosphorylated Smad2 identifies target tissues of TGFβ ligands in mouse development

Marie-Jose Goumans

Gene Expression Patterns, 2003

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Smad linker region phosphorylation is a signalling pathway in its own right and not only a modulator of canonical TGF-β signalling

Raafat Mohamed

Cellular and Molecular Life Sciences, 2019

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Phosphorylation of Smad7 at Ser-249 Does Not Interfere with Its Inhibitory Role in Transforming Growth Factor-β-dependent Signaling but Affects Smad7-dependent Transcriptional Activation

Serhiy Souchelnytskyi

Journal of Biological Chemistry, 2001

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Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

Rainer Heuchel, Carl-henrik Heldin

Nature, 1997

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Transcriptional regulation of Smad2 is required for enhancement of TGF?/Smad signaling by TGF? inducible early gene

Thomas Spelsberg

Journal of Cellular Biochemistry, 2002

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Evidence That Smad2 Is a Tumor Suppressor Implicated in the Control of Cellular Invasion

M. Mareel

Journal of Biological Chemistry, 1999

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Regulation of TGF-β signaling by Smad7

Xiaohua Yan

Acta Biochimica et Biophysica Sinica

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Identification of novel Smad2 and Smad3 associated proteins in response to TGF-β1

Brian Law

Journal of Cellular Biochemistry, 2008

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SMA-3 Smad Has Specific and Critical Functions in DBL-1/SMA-6 TGFβ-Related Signaling

Rafal Tokarz, Cathy Savage-dunn, Richard W Padgett

Developmental Biology, 2000

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Induction of Inhibitory Smad6 and Smad7 mRNA by TGF-β Family Members

Carl-henrik Heldin

Biochemical and Biophysical Research Communications, 1998

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Smad3 and Smad4 Mediate Transcriptional Activation of the Human Smad7 Promoter by Transforming Growth Factor beta

Markus Bitzer

Journal of Biological Chemistry, 2000

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Small C-terminal domain phosphatases dephosphorylate the regulatory linker regions of Smad2 and Smad3 to enhance transforming growth factor-β signaling

Danielle Martinez

Journal of Biological …, 2006

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TGF-beta-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines

Stephen Fink

Oncogene, 2003

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TGF-β-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines

Stephen Fink

Oncogene, 2003

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Genomic locus and promoter region of rat Smad7, an important antagonist of TGFβ signaling

Wilhelm Ansorge

Mammalian Genome, 2000

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Nucleocytoplasmic Shuttling of Smads 2, 3, and 4 Permits Sensing of TGF-β Receptor Activity

FRANCISCO JOSE NICOLAS

Molecular Cell, 2002

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Restoration of Transforming Growth Factor Signaling by Functional Expression of Smad4 Induces Anoikis

Robert Bookstein

2002

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The Oncoprotein Ski Acts as an Antagonist of Transforming Growth Factor- Signaling by Suppressing Smad2 Phosphorylation

Céline Prunier

Journal of Biological Chemistry, 2003

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Nuclear Export of Smad2 and Smad3 by RanBP3 Facilitates Termination of TGF-β Signaling

Chenbei Chang

Developmental Cell, 2009

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Smad7 Differentially Regulates Transforming Growth Factor β-mediated Signaling Pathways

Andrew Sizeland

Journal of Biological Chemistry, 1999

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Smad proteins and transforming growth factor-beta signaling

Markus Bitzer

Kidney international. Supplement

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Structural determinants of Smad function in TGF-β signaling

Maria Macias

Trends in Biochemical Sciences, 2015

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TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4

Serhiy Souchelnytskyi

The EMBO Journal, 1997

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Protein Kinase A Modulates Transforming Growth Factor- Signaling through a Direct Interaction with Smad4 Protein

Michael Uhler

Journal of Biological Chemistry, 2013

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