Structural studies of receptor binding by cholera toxin mutants (original) (raw)
Surprising leads for a cholera toxin receptor-binding antagonist: crystallographic studies of CTB mutants
Randall Holmes
Structure, 1995
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Novel Binding Site Identified in a Hybrid between Cholera Toxin and Heat-Labile Enterotoxin: 1.9 Å Crystal Structure Reveals the Details
Mats Ökvist
Structure, 2007
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Novel Binding Site Identified in a Hybrid between Cholera Toxin and Heat-Labile Enterotoxin
Mats Ökvist
Structure, 2004
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Crystal Structures Exploring the Origins of the Broader Specificity of Escherichia coli Heat-Labile Enterotoxin Compared to Cholera Toxin
Mats Ökvist
Journal of Molecular Biology, 2011
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Crystal structure of a new heat-labile enterotoxin, LT-IIb
Randall Holmes
Structure, 1996
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(1)H, (13)C, (15)N backbone assignment of the human heat-labile enterotoxin B-pentamer and chemical shift mapping of neolactotetraose binding
Per Kristiansen
Biomolecular NMR assignments, 2017
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Using a galactose library for exploration of a novel hydrophobic pocket in the receptor binding site of the Escherichia coli heat-labile enterotoxin
C. Verlinde
1999
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Hetero-multivalent binding of cholera toxin subunit B with glycolipid mixtures
Hung-jen Wu
Colloids and Surfaces B: Biointerfaces, 2017
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Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile
Jamshid Tanha
Journal of Biological Chemistry, 2013
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Binding efficiencies of carbohydrate ligands with different genotypes of cholera toxin B: molecular modeling, dynamics and docking simulation studies
sunil kumar
Journal of Molecular Modeling, 2012
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Two-dimensional structures of the Shiga toxin B-subunit and of a chimera bound to the glycolipid receptor Gb3
Sergio Marco
Journal of Structural Biology, 2002
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Structural diversity in a conserved cholera toxin epitope involved in ganglioside binding
Menachem Shoham
Protein Science, 2008
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A mutant Shiga-like toxin IIe bound to its receptor Gb3: structure of a group II Shiga-like toxin with altered binding specificity
Clifford Clark
Structure, 2000
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A mutational analysis of residues in cholera toxin A1 necessary for interaction with its substrate, the stimulatory g protein gsα
Randall Holmes
Toxins, 2015
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Fucosylation and protein glycosylation create functional receptors for cholera toxin
Andrea Rodriguez
eLife, 2015
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The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication
Yi-An Yang
PLOS Pathogens
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The 1.25 Å resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site
Randall Holmes
Journal of Molecular Biology, 1998
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A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity
Wayne Lencer
Proceedings of the National Academy of Sciences, 2001
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New insights into the structure-function relationships and therapeutic applications of cholera-like enterotoxins
Lolke de Haan
International Journal of Medical Microbiology, 2001
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Structural inferences for Cholera toxin mutations in Vibrio cholerae
Paul Shapshak
Bioinformation, 2011
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Structural Basis for the Differential Toxicity of Cholera Toxin and Escherichia coli Heat-labile Enterotoxin
Abu Tholib Aman
Journal of Biological Chemistry, 1999
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An association of 27- and 40-kDa molecules with glycolipids that bind A-B bacterial enterotoxins to cultured cells
Takashi Hamabata
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003
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Effects of Saccharide Spacing and Chain Extension on Toxin Inhibition by Glycopolypeptides of Well-Defined Architecture
brian polizzotti
Macromolecules, 2007
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Crystal structure of a biologically inactive mutant of toxic shock syndrome toxin-1 at 2.5 A resolution
Conrad P Quinn
Protein Science, 1996
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Genetic engineering of snake toxin. Role of invariant residues in the structural and functional properties of a curaremimetic toxin, as probed by site-directed mutagenesis
Sophie Zinn-justin
Journal of Biological Chemistry
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Cholera Toxin B Subunits Assemble into Pentamers - Proposition of a Fly-Casting Mechanism
Jihad Zrimi
PLoS ONE, 2010
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Multivalent binding of toxin A from Clostridium difficile to carbohydrate receptors
Margriet Jansze
Toxicon, 1994
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Identification of a conserved membrane localization domain within numerous large bacterial protein toxins
Brett Geissler
Proceedings of the National Academy of Sciences, 2010
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Mechanism of action of cholera toxin: effect of receptor density and multivalent binding on activation of adenylate cyclase
Esat Atikkan
Journal of Membrane Biology, 1980
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Sugar-induced conformational change found in the HA-33/HA-17 trimer of the botulinum toxin complex
Ken Inui
Biochemical and Biophysical Research Communications, 2013
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