Characterization of new PPARγ agonists: Benzimidazole derivatives—importance of positions 5 and 6, and computational studies on the binding mode (original ) (raw )Indanylacetic Acid Derivatives Carrying 4-Thiazolyl-phenoxy Tail Groups, a New Class of Potent PPAR α/γ/δ Pan Agonists: Synthesis, Structure−Activity Relationship, and In Vivo Efficacy
fernando dela cruz
Journal of Medicinal Chemistry, 2007
View PDFchevron_right
N -(2-Benzoylphenyl)- l -tyrosine PPARγ Agonists. 2. Structure−Activity Relationship and Optimization of the Phenyl Alkyl Ether Moiety
Wallace Harrington
Journal of Medicinal Chemistry, 1998
View PDFchevron_right
Common binding requirements of PPAR-α/δ/γ pan agonists: quantitative structure–activity relationship analysis of indanylacetic acid derivatives carrying 4-thiazolyl-phenoxy tail group
Divya Yadav
Medicinal Chemistry Research
View PDFchevron_right
1,3-Diphenyl-1H-pyrazole derivatives as a new series of potent PPARγ partial agonists
Young Yang
Bioorganic & Medicinal Chemistry, 2010
View PDFchevron_right
Benzothiazole-based N-(phenylsulfonyl)amides as a novel family of PPARα antagonists
Letizia Giampietro
Bioorganic & Medicinal Chemistry Letters, 2011
View PDFchevron_right
Structure–activity relationships of dimeric PPAR agonists
Jan Nehlin
Bioorganic & Medicinal Chemistry Letters, 2005
View PDFchevron_right
A Comparative Study on Selective PPAR Modulators Through Quantitative Structure-Activity Relationship, Pharmacophore and Docking Analyses
Kunal Roy
Current computer-aided drug design, 2017
View PDFchevron_right
Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPARγ partial agonist
David Virley
Bioorganic & Medicinal Chemistry Letters, 2011
View PDFchevron_right
Design, synthesis and computational validation of novel benzimidazole/indole-based PPARα and PPARγ partial agonists
Raman Verma
Journal of Chemical Sciences, 2013
View PDFchevron_right
Design, Synthesis and Virtual Screening of Certain 2-PYRAZOLIN-5-ONE and PYRAZOLIDINE-3, 5- Dione Derivatives as Potential Ppar Agonists
maiy jaballah
View PDFchevron_right
Discovery of GSK1997132B a novel centrally penetrant benzimidazole PPAR? partial agonist
David Virley
Bioorg Medicinal Chem Letter, 2011
View PDFchevron_right
A combined ligand and structure based approach to design potent PPAR-alpha agonists
Gaurao Dhoke
Journal of Molecular Structure, 2012
View PDFchevron_right
Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618
Calin Steindal
European Journal of Medicinal Chemistry
View PDFchevron_right
DESIGN, IN SILICO DOCKING AND PREDICTIVE ADME PROPERTIES OF SOME THIAZOLIDINE-2, 4-DIONES DERIVATIVES AS PPARγ MODULATORS
International Journal of Pharmacy and Pharmaceutical Sciences (IJPPS)
International Journal of Pharmacy and Pharmaceutical Sciences, 2016
View PDFchevron_right
Structural insights for the design of new PPARgamma partial agonists with high binding affinity and low transactivation activity
Mayte Blay
Journal of Computer-Aided Molecular Design, 2011
View PDFchevron_right
Benzoxazinones as PPARγ agonists. part 1: SAR of three aromatic regions
Ignatius Turchi
Bioorganic & Medicinal Chemistry Letters, 2003
View PDFchevron_right
3,4,5-Trisubstituted isoxazoles as novel PPARδ agonists. Part 2
Mihai Azimioara
Bioorganic & Medicinal Chemistry Letters, 2006
View PDFchevron_right
METHYLCHROMONYL LINKED BENZYLIDENES AS NOVEL PARTIAL PPARγ AGONISTS: SYNTHESIS, CHARACTERIZATION AND DOCKING STUDIES
IJAR Indexing
View PDFchevron_right
Indolyl linked meta-substituted benzylidene-based novel PPAR ligands: synthetic and docking studies
Raman Verma
Medicinal Chemistry Research, 2014
View PDFchevron_right
Identification of a PPARδ agonist with partial agonistic activity on PPARγ
Alex zhang
Bioorganic & Medicinal Chemistry Letters, 2009
View PDFchevron_right
Benzoyl 2-methyl indoles as selective PPARγ modulators
Joel Berger
Bioorganic & Medicinal Chemistry Letters, 2005
View PDFchevron_right
Novel Phenoxazinones as potent agonist of PPAR-α: design, synthesis, molecular docking and in vivo studies
David Ugwu
Lipids in Health and Disease
View PDFchevron_right
Development of Improved PPARβ/δ Inhibitors
Wibke Diederich
ChemMedChem, 2012
View PDFchevron_right
Agonism activities of lyso-phosphatidylcholines (LPC) Ligands binding to peroxisome proliferator-activated receptor gamma (PPARγ)
jiayue wang
Journal of Biomolecular Structure and Dynamics, 2019
View PDFchevron_right
Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARγ agonists
Philippe Chavatte
Bioorganic & Medicinal Chemistry, 2006
View PDFchevron_right
Structure-Based Drug Design of a Novel Family of PPARγ Partial Agonists: Virtual Screening, X-ray Crystallography, and in Vitro/in Vivo Biological Activities
Chiung-tong Chen
Journal of Medicinal Chemistry, 2006
View PDFchevron_right
Scholars Research Library Understanding allosteric modulation in PPARγ receptors by comparative QSAR analysis
RAM BABU TRIPATHI
View PDFchevron_right
Design of a partial PPARδ agonist
Eva Johansson
Bioorganic & Medicinal Chemistry Letters, 2007
View PDFchevron_right
Rational design and synthesis of some PPAR-g agonists: Substituted benzylideneamino-benzylidene-thiazolidine-2,4-diones
Dr. Animeshchandra haldar
View PDFchevron_right
Synthesis and docking studies of novel antitumor benzimidazoles
Sean Kerwin
Bioorganic & Medicinal Chemistry, 2012
View PDFchevron_right
Imidazoline-1 Receptor Ligands as Apoptotic Agents: Pharmacophore Modeling and Virtual Docking Study
Katarina Nikolic
Combinatorial Chemistry & High Throughput Screening, 2013
View PDFchevron_right
Selective PPARγ modulators with improved pharmacological profiles
Joel Berger
Bioorganic & Medicinal Chemistry Letters, 2005
View PDFchevron_right