cis Expression of the F12 Human Immunodeficiency Virus (HIV) Nef Allele Transforms the Highly Productive NL4-3 HIV Type 1 to a Replication-Defective Strain: Involvement of both Env gp41 and CD4 Intracytoplasmic Tails (original) (raw)

Nef from Human Immunodeficiency Virus Type 1F12 Inhibits Viral Production and Infectivity

Paola D'Aloja

Journal of Virology, 2001

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Genetic and functional analysis of the human immunodeficiency virus (HIV) type 1-inhibiting F12-HIVnef allele

Paola D'Aloja

The Journal of general virology, 2001

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Internalization and intracellular retention of CD4 are two separate functions of the human immunodeficiency virus type 1 Nef protein

Margherita Doria

Journal of General Virology, 2007

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Functional characterization of HIV-1 Nef mutants in the context of viral infection

Olivier Schwartz

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Structural Basis of CD4 Downregulation by HIV-1 Nef

Yonghwa Kwon

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HIV-1 Nef: at the crossroads

Victor Garcia

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Biology of the HIV Nef protein

Suman Das

The Indian journal of medical research, 2005

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HIV-1 Nef control of cell signalling molecules: Multiple strategies to promote virus replication

Dale McPhee

Journal of Biosciences, 2003

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Effects of the exogenous Nef protein on HIV-1 target cells

Caterina Martini

Cell Biochemistry and Function, 1999

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Inhibition of HIV1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein

Alp Oran

Current Biology, 1999

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CD4 Down-regulation by HIV-1 and Simian Immunodeficiency Virus (SIV) Nef Proteins Involves Both Internalization and Intracellular Retention Mechanisms

Katy Janvier

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HIV-1 Nef Transfer and Intracellular Signalling in Uninfected Cells

Elisabetta Affabris

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Determinants in HIV1 Nef for enhancement of virus replication and depletion of CD4+ T lymphocytes in human lymphoid tissue ex vivo

Serkan Sertel

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Nef Alleles from Human Immunodeficiency Virus Type 1-Infected Long-Term-Nonprogressor Hemophiliacs with or without Late Disease Progression Are Defective in Enhancing Virus Replication and CD4 Down-Regulation

Andrea Crotti

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Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis

MARY MORENO

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CD4 downregulation by the human immunodeficiency virus type 1 Nef protein is dispensable for optimal output and functionality of viral particles in primary T cells

Stefania Petrini

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Nef-Induced CD4 Downregulation: a Diacidic Sequence in Human Immunodeficiency Virus Type 1 Nef Does Not Function as a Protein Sorting Motif through Direct Binding to -COP

Olivier Schwartz

Journal of Virology, 2001

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gag, vif, and nef genes contribute to the homologous viral interference induced by a nonproducer human immunodeficiency virus type 1 (HIV-1) variant: identification of novel HIV-1-inhibiting viral protein mutants

D. Pedacchia, Paola D'Aloja

Journal of virology, 1998

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Enhancement of human immunodeficiency virus type 1 infectivity by Nef is producer cell-dependent

Akari Miller

1998

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Nef Enhances Human Immunodeficiency Virus Type 1 Infectivity Resulting from Intervirion Fusion: Evidence Supporting a Role for Nef at the Virion Envelope

M. Pizzato

Journal of Virology, 2001

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Potent Enhancement of HIV-1 Replication by Nef in the Absence of SERINC3 and SERINC5

Heinrich Gőttlinger

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Human immunodeficiency virus type 1 (HIV-1) provirus expression and LTR transcription are repressed in NEF-expressing cell lines

Nafees Ahmad

Virology, 1991

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Nef proteins from HIV-1 elite controllers are inefficient at preventing ADCC

George Lewis

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Nef-Induced CD4 Downregulation: a Diacidic Sequence in Human Immunodeficiency Virus Type 1 Nef Does Not Function as a Protein Sorting Motif through Direct Binding to b-COP

Olivier Schwartz

J Virol, 2001

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Virological Importance of the Protease-Cleavage Site in Human Immunodeficiency Virus Type 1 Nef Is Independent of both Intravirion Processing and CD4 Down-regulation

Jacques Corbeil

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HIV-1 Nef mutations abrogating downregulation of CD4 affect other Nef functions and show reduced pathogenicity in transgenic mice

Patrick Vincent

Virology, 2006

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Coreceptor Phenotype of Natural Human Immunodeficiency Virus with Nef Deleted Evolves In Vivo, Leading to Increased Virulence

Dominique Schols

Journal of Virology, 2002

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SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

Heinrich Gőttlinger

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Nef: “Necessary and Enforcing Factor” in HIV Infection

Ajith Joseph

Current Hiv Research, 2005

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Down-modulation of HIV-1 LTR activity by an extra-LTR nef gene fragment

R. Brack-werner

Virology, 1996

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Cellular Functions of the Human Immunodeficiency Virus Type 1 (HIV-1) Nef Protein

Aki Manninen

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Human Immunodeficiency Virus Type 1 Nef: Adapting to Intracellular Trafficking Pathways

Kathleen Collins

Microbiology and Molecular Biology Reviews, 2006

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