Granular cell tumors of the tracheobronchial tree (original) (raw)
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Pediatric granular cell tumor of the tracheobronchial tree
Journal of Pediatric Surgery, 2008
Granular cell tumors are lesions of neural crest origin with a predilection for the skin and soft tissue. Granular cell tumors of the tracheobronchial tree are exceedingly rare in the pediatric population, with only 5 reported cases. All 5 of these lesions presented within the cervical trachea. We report a large granular cell tumor in the posterior mediastinum, densely adherent to the intrathoracic tracheal carina.
Diagnostic Cytopathology, 2000
We report on a case of extraluminal tracheal granular-cell tumor which was interpreted as a Hurthle-cell neoplasm of the thyroid on fine-needle aspirate. Review of the literature reveals only one other such case. The patient was a 35-yr-old female who presented with an enlarged thyroid. Aspiration cytology revealed a syncytium of cells with abundant granular cytoplasm interpreted as a thyroid follicular neoplasm with Hurthle-cell change. However, histology of the resection specimen with immunohistochemistry confirmed it as a granular-cell tumor. The cytologic differential diagnosis of neoplasms with oncocytoid cytoplasm in and around the thyroid should include granular-cell tumor of the trachea.
Multiphasic multidetector computed tomography study of a rare tracheal tumor: granular cell tumor
Case reports in pulmonology, 2014
Our aim is to present the case report of a woman affected by tracheal granular cell tumor analysed by multiphasic contrast-enhanced multidetector CT. The tumor presents as polypoid lesion (diameter 13 mm), with smooth and well-defined margins, elevated contrast enhancement in arterial phase, and a modest release of contrast in venous phase. This pattern is quite different from the other tracheal tumours. We have performed a comprehensive review of literature to assess all cases of granular cell tumors of the trachea; only 40 cases are reported. Of these, no one focused on the contrast enhancement aspect, so our work is the first showing a specific pattern in multidetector computed tomography (MDCT) of the tracheal granular cell tumour and may help in differential diagnosis.
Journal of Pediatric Surgery, 2006
Bronchial granular cell tumor is an uncommon tumor in young children. Recurrent pneumonia in the same site should raise suspicion of an obstructing granular cell tumor of the bronchus. We present a 10-year-old girl with an 18-month history of recurrent pneumonia caused by obstruction of the main lingular bronchus by this type of tumor. In our patient, an upper left lobectomy was only technically feasible instead of a lingulectomy alone because of the spread pulmonary inflammation and the depth of bronchial wall invasion by the tumor. Delayed diagnosis resulted in a more extensive pulmonary resection. D
Laryngeal granular cell tumor; rare location
Acta medica (Hradec Králové) / Universitas Carolina, Facultas Medica Hradec Králové, 2011
Granular cell tumors are benign subcutaneous or submucosal lesions of neurogenic origin. In this case study one patient was diagnosed and treated successfully with complete surgical resection of a laryngeal granular cell tumor that was originated from the left arytenoid region that very rare location. There is no evidence of recurrence 2 years after surgery. Granular cell tumors should be considered in the differential diagnosis of laryngeal masses, particularly in the posterior glottis.
Granular cell tumour of the larynx - A case report
Ghana Medical Journal, 2016
Granular cell tumours (GCTs) are benign tumours rarely found in the larynx even though they are common in the head and neck region. The laryngeal tumour may be asymptomatic but typically patients present with hoarseness of voice, stridor, haemoptysis and dysphagia. The lesion can mimic squamous cell thus deep biopsy must be taken with adjacent normal tissue to confirm this pathology. Immunohistochemical staining is also used. Complete surgical resection of this tumour is the treatment of choice. We present a 25 year old woman with a laryngeal granular cell tumour involving the right vocal cord diagnosed after direct laryngoscopy and biopsy. She was treated by right cordectomy via a laryngofissure approach. We present the case due to the rarity of the laryngeal granular cell tumour and the need to highlight the importance of taking deep biopsies. If biopsies are superficial, an inexperienced pathologist would mistake it for well differentiated carcinoma.