Identification of a juxtamembrane mechanosensitive domain in the platelet mechanosensor glycoprotein Ib-IX complex (original) (raw)
Platelet clearance via shear-induced unfolding of a membrane mechanoreceptor
Renhao Li, Wei Deng
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The N-terminal Flanking Region of the A1 Domain Regulates the Force-dependent Binding of von Willebrand Factor to Platelet Glycoprotein Ib
Miguel Cruz
Journal of Biological Chemistry, 2013
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Von Willebrand factor-A1 domain binds platelet glycoprotein Ibα in multiple states with distinctive force-dependent dissociation kinetics
Fangyuan Zhou
Thrombosis Research, 2015
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von Willebrand factor self-association on platelet GpIb alpha under hydrodynamic shear: effect on shear-induced platelet activation
Dr ishwar singh
2010
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von Willebrand factor self-association on platelet GpIbα under hydrodynamic shear: effect on shear-induced platelet activation
indrajeet kumar Singh
Blood, 2010
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Destabilization of the A1 Domain in von Willebrand Factor Dissociates the A1A2A3 Tri-domain and Provokes Spontaneous Binding to Glycoprotein Ib and Platelet Activation under Shear Stress
Erik Sedlák
Journal of Biological Chemistry, 2010
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O-linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditions
Agata Nowak
Blood, 2012
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Platelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ib
Hans Deckmyn
Haematologica, 2013
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Ultralarge multimers of von Willebrand factor form spontaneous high-strength bonds with the platelet glycoprotein Ib-IX complex: studies using optical tweezers
Bahman Anvari
Blood, 2002
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The von Willebrand Factor-Glycoprotein Ib/V/IX Interaction Induces Actin Polymerization and Cytoskeletal Reorganization in Rolling Platelets and Glycoprotein Ib/V/IX-transfected Cells
Warwick Nesbitt
Journal of Biological Chemistry, 1999
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Regulation of von Willebrand Factor Binding to the Platelet Glycoprotein Ib-IX by a Membrane Skeleton-dependent Inside-out Signal
Richard Bodnar
Journal of Biological Chemistry, 2001
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Shear Stress-Induced Binding of Large and Unusually Large von Willebrand Factor to Human Platelet Glycoprotein Ibα
Chester Li
Annals of Biomedical Engineering, 2000
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Filamin A binding to the cytoplasmic tail of glycoprotein Ib regulates von Willebrand factor-induced platelet activation
Julio c Resendiz
2003
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Importance of Temporal Flow Gradients and Integrin IIb 3 Mechanotransduction for Shear Activation of Platelets
Warwick Nesbitt
Journal of Biological Chemistry, 2005
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Platelet glycoprotein Ibα forms catch bonds with human WT vWF but not with type 2B von Willebrand disease vWF
Tadayuki Yago
Journal of Clinical Investigation, 2008
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Integrated system investigating shear-mediated platelet interactions with von Willebrand factor using microliters of whole blood
Brian Maccraith
2010
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Platelets and physics: How platelets “feel” and respond to their mechanical microenvironment
Wilbur Lam
Blood Reviews, 2015
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Platelet integrins exhibit anisotropic mechanosensing and harness piconewton forces to mediate platelet aggregation
Wilbur Lam
Proceedings of the National Academy of Sciences of the United States of America, 2017
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Crystal Structure of the von Willebrand Factor A1 Domain and Implications for the Binding of Platelet Glycoprotein Ib
Miguel Cruz
Journal of Biological Chemistry, 1998
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Long-Ranged Protein-Glycan Interactions Stabilize Von Willebrand Factor A2 Domain from Mechanical Unfolding
Alparslan Oztekin
Biophysical Journal, 2019
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Purified A2 domain of von Willebrand factor binds to the active conformation of von Willebrand factor and blocks the interaction with platelet glycoprotein Ib
lucia morales
Journal of Thrombosis and Haemostasis, 2007
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Title Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion , spreading , and activation Permalink
Wilbur Lam
2014
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Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow
Hans Deckmyn
Blood, 2011
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von Willebrand factor binding to platelet glycoprotein Ib-IX-V stimulates the assembly of an alpha-actinin-based signaling complex
Julio c Resendiz
Journal of Thrombosis and Haemostasis, 2004
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Article Force-Sensitive Autoinhibition of the von Willebrand Factor Is Mediated by Interdomain Interactions
Dmitry Kolyanov
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Circulating but not immobilized N-deglycosylated von Willebrand factor increases platelet adhesion under flow conditions
Achim Wixforth
Biomicrofluidics, 2013
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Changes in Thermodynamic Stability of von Willebrand Factor Differentially Affect the Force-Dependent Binding to Platelet GPIbα
Erik Sedlák
Biophysical Journal, 2009
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The platelet glycoprotein Ib-von Willebrand factor interaction activates the collagen receptor 2 1 to bind collagen: activation-dependent conformational change of the 2-I domain
Miguel Cruz
Blood, 2005
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Mechanics of transient platelet adhesion to von Willebrand factor under flow
O. Lomakin
Biophysical journal, 2005
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Dynamic Force Spectroscopy of Glycoprotein Ib-IX and von Willebrand Factor
Bahman Anvari
Biophysical Journal, 2005
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Shielding of the A1 Domain by the D'D3 Domains of von Willebrand Factor Modulates Its Interaction with Platelet Glycoprotein Ib-IX-V
Hans Deckmyn
Journal of Biological Chemistry, 2006
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Identification of Peptide Antagonists to Glycoprotein Ibα That Selectively Inhibit von Willebrand Factor Dependent Platelet Aggregation
Jaison Thomas
Biochemistry, 2008
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Characterization of Murine Anti-Glycoprotein Ib Monoclonal Antibodies That Differentiate between Shear-Induced and Ristocetin/Botrocetin-Induced Glycoprotein Ib-von Willebrand Factor Interaction
Marc Hoylaerts
Pathophysiology of Haemostasis and Thrombosis, 2000
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