von Willebrand factor binding to platelet glycoprotein Ib-IX-V stimulates the assembly of an alpha-actinin-based signaling complex (original) (raw)

Pathological Shear Stress Stimulates the Tyrosine Phosphorylation of α-Actinin Associated with the Glycoprotein Ib-IX Complex

Julio c Resendiz

Biochemistry, 2002

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Paradoxical Effect of Nonphysiological Shear Stress on Platelets and von Willebrand Factor

Dr. Nandan K Mondal

Artificial organs, 2015

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von Willebrand factor self-association on platelet GpIb alpha under hydrodynamic shear: effect on shear-induced platelet activation

Dr ishwar singh

2010

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The von Willebrand Factor-Glycoprotein Ib/V/IX Interaction Induces Actin Polymerization and Cytoskeletal Reorganization in Rolling Platelets and Glycoprotein Ib/V/IX-transfected Cells

Warwick Nesbitt

Journal of Biological Chemistry, 1999

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Importance of Temporal Flow Gradients and Integrin IIb 3 Mechanotransduction for Shear Activation of Platelets

Warwick Nesbitt

Journal of Biological Chemistry, 2005

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Shear Stress-Induced Binding of Large and Unusually Large von Willebrand Factor to Human Platelet Glycoprotein Ibα

Chester Li

Annals of Biomedical Engineering, 2000

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Destabilization of the A1 Domain in von Willebrand Factor Dissociates the A1A2A3 Tri-domain and Provokes Spontaneous Binding to Glycoprotein Ib and Platelet Activation under Shear Stress

Erik Sedlák

Journal of Biological Chemistry, 2010

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von Willebrand factor self-association on platelet GpIbα under hydrodynamic shear: effect on shear-induced platelet activation

indrajeet kumar Singh

Blood, 2010

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Platelet Activation via Shear Stress Exposure Induces a Differing Pattern of Biomarkers of Activation versus Biochemical Agonists

Yana Roka Moiia

Thrombosis and Haemostasis, 2020

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Activation and shedding of platelet glycoprotein IIb/IIIa under non-physiological shear stress

Mark S. Slaughter

Molecular and cellular biochemistry, 2015

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Shear-induced platelet receptor shedding by non-physiological high shear stress with short exposure time: Glycoprotein Ibα and glycoprotein VI

Dr. Nandan K Mondal

Thrombosis research, 2015

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Inhibition of Shear-Stress-Induced Platelet Aggregation and Phosphotyrosine Signaling by GPIIb–IIIa Antagonists

Steven Slack

Annals of Biomedical Engineering, 2000

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Thrombospondin-1 mediates platelet adhesion at high shear via glycoprotein Ib (GPIb): an alternative/backup mechanism to von Willebrand factor

David Varon, Beate Kehrel

The FASEB Journal, 2003

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Activation of pp125FAK by type 2B recombinant von Willebrand factor binding to platelet GPIb at a high shear rate occurs independently of alphaIIbbeta3 engagement

Dominique Baruch

Blood, 2003

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ATP Augments von Willebrand Factor-dependent Shear-induced Platelet Aggregation through Ca2+Calmodulin and Myosin Light Chain Kinase Activation

Cécile Oury

Journal of Biological Chemistry, 2004

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Shear-mediated platelet activation in the free flow II: Evolving mechanobiological mechanisms reveal an identifiable signature of activation and a bi-directional platelet dyscrasia with thrombotic and bleeding features

Samuel Gutierrez

Journal of Biomechanics, 2021

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Platelet interaction with von Willebrand factor is enhanced by shear-induced clustering of glycoprotein Ib

Hans Deckmyn

Haematologica, 2013

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Purinergic P2Y12 Receptor Blockade Inhibits Shear-Induced Platelet Phosphatidylinositol 3Kinase Activation

Julio c Resendiz

Molecular Pharmacology, 2003

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p21 activated kinase signaling coordinates glycoprotein receptor VI-mediated platelet aggregation, lamellipodia formation, and aggregate stability under shear

Joseph Aslan, Jonathan Chernoff

Arteriosclerosis, thrombosis, and vascular biology, 2013

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Platelet Aggregation Induced by a Monoclonal Antibody to the A1 Domain of von Willebrand Factor

hans deckmyn

Blood, 1998

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ACTIVATION OF pp125FAK BY TYPE 2B RECOMBINANT VON WILLEBRAND FACTOR BINDING TO PLATELET GPIb AT HIGH SHEAR RATE OCCURS

Dominique Baruch

2003

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Filamin A binding to the cytoplasmic tail of glycoprotein Ib regulates von Willebrand factor-induced platelet activation

Julio c Resendiz

2003

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Key role of glycoprotein Ib/V/IX and von Willebrand factor in platelet activation-dependent fibrin formation at low shear flow

Hans Deckmyn

Blood, 2011

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A New Role for P-Selectin in Shear-Induced Platelet Aggregation

Perumal Thiagarajan

Circulation, 2000

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The Role of a Disintegrin and Metalloproteinase Proteolysis and Mechanical Damage in Nonphysiological Shear Stress-Induced Platelet Receptor Shedding

katherin arias

ASAIO Journal, 2019

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Activation of pp125FAK by type 2B recombinant von Willebrand factor binding to platelet GPIb at a high shear rate occurs independently of αIIbβ3 engagement

Abdel Saci

Blood, 2003

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Integrated system investigating shear-mediated platelet interactions with von Willebrand factor using microliters of whole blood

Brian Maccraith

2010

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The effect of glycoprotein IIb-IIIa receptor occupancy on the cytoskeleton of resting and activated platelets

Lewis Coons

Journal of Biological Chemistry, 1991

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Mechanism of platelet adhesion to von Willebrand factor and microparticle formation under high shear stress

Harry Heijnen

Blood, 2006

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High shear induces platelet dysfunction leading to enhanced thrombotic propensity and diminished hemostatic capacity

Dr. Nandan K Mondal

Platelets, 2017

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Abstracts of papers presented at the XIXth European Platelet Meeting, 14th–16th October 2004, Dorint Resort & Spa, Bad Brückenau, Germany

Sabine Gruener

Platelets, 2005

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Regulation of von Willebrand Factor Binding to the Platelet Glycoprotein Ib-IX by a Membrane Skeleton-dependent Inside-out Signal

Richard Bodnar

Journal of Biological Chemistry, 2001

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Circulating Activated Platelets Assist THP-1 Monocytoid/Endothelial Cell Interaction Under Shear Stress

claude remacle

Blood, 1999

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The N-terminal Flanking Region of the A1 Domain Regulates the Force-dependent Binding of von Willebrand Factor to Platelet Glycoprotein Ib

Miguel Cruz

Journal of Biological Chemistry, 2013

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Inhibition of adhesive and signaling functions of the platelet GPIb-V-IX complex by a cell penetrating GPIbα peptide

Tovo David

Journal of Thrombosis and Haemostasis, 2006

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