Lipase-Catalyzed Enantioselective Hydrolysis of Bis(acyloxymethyl) 1,4-Dihydro-3,5-pyridinedicarboxylates Leading to Optically Active Medicines (original) (raw)

Lipase-catalyzed enantioselective hydrolysis of methyl 2-fluoro-2-arylpropionates in water-saturated isooctane

Renzo Ruzziconi

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Carica papaya lipase: a novel biocatalyst for the enantioselective hydrolysis of (R,S)-naproxen 2,2,2-trifluoroethyl ester

Shau-Wei Tsai

Enzyme and Microbial Technology, 2005

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Hydrolytic resolution of (R,S)-naproxen 2,2,2-trifluoroethyl thioester byCarica papaya lipase in water-saturated organic solvents

Shau-Wei Tsai

Biotechnology and Bioengineering, 2005

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On the enzymatic hydrolysis of methyl 2-fluoro-2-arylpropionates by lipases

Renzo Ruzziconi

Tetrahedron, 2005

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Enantioselective esterification of (RS)-2-(4-chlorophenoxy)propionic acid via Carica papaya lipase in organic solvents

Shau-Wei Tsai

Tetrahedron: Asymmetry, 2004

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Effect of Acyl Chain Length and Branching on the Enantioselectivity of Candida r ugosa Lipase in the Kinetic Resolution of 4-(2-Difluoromethoxyphenyl)-Substituted 1,4-Dihydropyridine 3,5-Diesters

Brigita Vigante

The Journal of Organic Chemistry, 2002

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Partially purified Carica papaya lipase: a versatile biocatalyst for the hydrolytic resolution of ( R,S )-2-arylpropionic thioesters in water-saturated organic solvents

Shau-Wei Tsai

Biotechnology and Bioengineering, 2005

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Modulation of the enantioselectivity of Candida antarctica B lipase via conformational engineering. Kinetic resolution of (±)-α-hydroxy-phenylacetic acid derivatives

Cesar Mateo

Tetrahedron: Asymmetry, 2002

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Modulation of the Enantioselectivity of Candida Antarctica B Lipase via Conformational Engineering. Kinetic Resolution of (ą)-[Alpha]-Hydroxy-Phenylacetic Acid …

Manuel Fuentes

Tetrahedron: …, 2002

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Enantioselective resolution of side-chain modified gem-difluorinated alcohols catalysed by Candida antarctica lipase B and monitored by capillary electrophoresis

Václav Kašička

Bioorganic & Medicinal Chemistry, 2019

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A kinetic study of candida rugosa lipase-catalyzed synthesis of 4,6-dimethyl-3-cyano-2-pyridone

Zorica Knezevic-Jugovic

Journal of the Brazilian Chemical Society, 1997

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Enantioselective esterification of 2-arylpropionic acids and trans-2-phenyl-1-cyclohexanol: Comparison between immobilised lipases from Candida rugosa and Rhizomucor miehei

F. Valero

1998

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Preparation of the enantiomers of 1-phenylethan-1,2-diol. Regio- and enantioselectivity of acylase I and Candida antarctica lipases A and B

Liisa Kanerva

Tetrahedron: Asymmetry, 2001

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Modulation of the enantioselectivity of lipases via controlled immobilization and medium engineering: hydrolytic resolution of mandelic acid esters

Claudia Ortiz

Enzyme and Microbial Technology, 2002

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Immobilization of Candida rugosa lipase on glass beads for enantioselective hydrolysis of racemic Naproxen methyl ester

elif can

Bioresource Technology, 2011

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Kinetic Resolution of Profens by EnantioselectiveEsterification Catalyzed by Candida antarctica and Candida rugosa Lipases

Michał Marszałł

Chirality, 2014

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Lipase catalysis in the optical resolution of 2-amino-1-phenylethanol derivatives

Liisa Kanerva

Journal of the Chemical Society, Perkin Transactions 1, 1992

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Dynamic kinetic resolution of (R, S)-naproxen 2, 2, 2-trifluoroethyl ester via lipase-catalyzed hydrolysis in micro-aqueous isooctane

Shau-Wei Tsai

Journal of Molecular Catalysis B: Enzymatic, 2003

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Investigation of lipases from various Carica papaya varieties for hydrolysis of olive oil and kinetic resolution of (R,S)-profen 2,2,2-trifluoroethyl thioesters

Shau-Wei Tsai

Process Biochemistry, 2006

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Enzymatic production of (3S,4R)-(−)-4-(4′-fluorophenyl)-6-oxo-piperidin-3-carboxylic acid using a commercial preparation from Candida antarctica A: the role of a contaminant esterase

Manuel Fuentes

Tetrahedron: Asymmetry, 2002

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Regio- and enantioselective esterifications of polyoxygenated compounds catalyzed by lipases

Bernardo Herradón

Tetrahedron: Asymmetry, 1993

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Lipase-catalysed kinetic resolution in organic solvents: an approach to enantiopure α-methyl-β-alanine esters

Ferenc Fülöp

Tetrahedron: Asymmetry, 2002

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Carica papaya lipase-catalyzed transesterification resolution of secondary alcohols in organic solvents

Shau-Wei Tsai

Journal of the Taiwan Institute of Chemical Engineers, 2009

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Effective Method of Lipase-Catalyzed Enantioresolution of 6-Alkylsulfanyl-1,4-dihydropyridines

aleksandrs versilovskis

HETEROCYCLES, 2014

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Kinetics of Enantiomerically Enriched Synthesis of Solketal Esters Using Native and SBA-15 supported P. Fluorescens Lipase

Jolanta Bryjak

Chemical and Process Engineering, 2017

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Effects of medium and of reaction conditions on the enantioselectivity of lipases in organic solvents and possible rationales

Francesco Secundo

Tetrahedron: Asymmetry, 1992

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Enantiopreference of Candida antarctica lipase B toward carboxylic acids: Substrate models and enantioselectivity thereof

Shau-Wei Tsai

Journal of Molecular Catalysis B: Enzymatic, 2016

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Probing the substrate specificity for lipases. II. Kinetic and modeling studies on the molecular recognition of 2-arylpropionic esters by Candida rugosa and Rhizomucor miehei lipases

Simonetta Soro

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1997

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Lipases A and B from Candida antarctica in the enantioselective acylation of ethyl 3-heteroaryl-3-hydroxypropanoates: aspects on the preparation and enantiopreference

Florin Irimie

Tetrahedron-asymmetry, 2011

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Studies on the chemoenzymatic synthesis of (R)-and (S)-methyl 3-aryl-3-hydroxypropionates: the influence of toluene-pretreatment of lipase preparations on enantioselective transesterifications

Paweł Borowiecki

Tetrahedron Asymmetry

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Probing the substrate specificity for lipases. A CoMFA approach for predicting the hydrolysis rates of 2-arylpropionic esters catalyzed by Candida rugosa lipase

Simonetta Soro

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1996

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Highly enantioselective synthesis of long chain alkyl trifluoromethyl carbinols and β-thiotrifluoromethyl carbinols through lipases

Angel Guerrero

Tetrahedron Asymmetry, 1996

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