New Active HIV-1 Protease Inhibitors Derived from 3-Hexanol: Conformation Study of the Free Inhibitors in Crystalline State and in Complex with the Enzyme
Jindřich Hašek
Chemical Biology & Drug Design, 2012
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Structure-Based Design of HIV Protease Inhibitors: Sulfonamide-Containing 5,6-Dihydro-4-hydroxy-2-pyrones as Non-Peptidic Inhibitors
Barry Finzel
Journal of Medicinal Chemistry, 1996
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Pentacycloundecane-diol-Based HIV-1 Protease Inhibitors: Biological Screening, 2 D NMR, and Molecular Simulation Studies
Bahareh Honarparvar, Yasien Sayed
ChemMedChem, 2012
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Potent New Antiviral Compound Shows Similar Inhibition and Structural Interactions with Drug Resistant Mutants and Wild Type HIV-1 Protease †
Yuan-fang Wang, Irene Weber
Journal of Medicinal Chemistry, 2007
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Synthesis of 5,6-Dihydro-4-hydroxy-2- pyrones as HIV-1 Protease Inhibitors: The Profound Effect of Polarity on Antiviral Activity
Edmund Ellsworth
Journal of Medicinal Chemistry, 1997
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Inhibitors of HIV Protease: Unique Non‐peptide Active Site Templates
Christopher Gajda
Journal of Molecular Recognition, 1996
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Novel Protease Inhibitors (PIs) Containing Macrocyclic Components and 3(R),3a(S),6a(R)-bis-Tetrahydrofuranylurethane That Are Potent against Multi-PI-Resistant HIV-1 Variants In Vitro
Masayuki Amano
Antimicrobial Agents and Chemotherapy, 2010
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An Orally Bioavailable HIV1 Protease Inhibitor Containing an Imidazole-Derived Peptide Bond Replacement: Crystallographic and Pharmacokinetic Analysis
Sherin S. Abdel-Meguid
Biochemistry, 1994
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Design, Synthesis, and Biological and Structural Evaluations of Novel HIV-1 Protease Inhibitors To Combat Drug Resistance
Md Akbar Ali
Journal of Medicinal Chemistry, 2012
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Structure-Based Design of Novel HIV-1 Protease Inhibitors to Combat Drug Resistance
Hiroyuki Gatanaga
J. Med. …, 2006
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Discovery and optimization of nonpeptide HIV-1 protease inhibitors
John Domagala
Bioorganic & Medicinal Chemistry, 1996
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INHIBITORS OF HIV-1 PROTEASE: A Major Success of Structure-Assisted Drug Design 1
Alexander Wlodawer
Annual Review of Biophysics and Biomolecular Structure, 1998
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Crystal structures of multidrug-resistant HIV-1 protease in complex with two potent anti-malarial compounds
deepak gupta
Biochemical and Biophysical Research Communications, 2012
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The design, synthesis and evaluation of novel HIV-1 protease inhibitors with high potency against PI-resistant viral strains
Emilio Emini
Bioorganic & Medicinal Chemistry Letters, 2003
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Future appeal of comparative studies on putative binding sites of HIV-1 virus-encoded proteolytic enzyme inhibitor of different Food and Drug Administration-approved compounds
SAMI MELEBARI
HIV & AIDS Review
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Novel Insight into Inhibitor Binding of Highly Symmetric HIV-1 Protease
German Erlenkamp
ChemBioChem, 2008
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Design, Synthesis, Evaluation, and Crystallographic-Based Structural Studies of HIV1 Protease Inhibitors with Reduced Response to the V82A Mutation
F. Javier Sardina
Journal of Medicinal Chemistry, 2008
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Pentacycloundecane-based Inhibitors of Wild-type C-South African HIV Protease
Katja Petzold, Yasien Sayed
Bioorganic & medicinal …, 2011
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Potent 7-Hydroxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic Acid-Based Macrocyclic Inhibitors of Hepatitis C Virus NS3 Protease
Andrew Prongay
Journal of Medicinal Chemistry, 2006
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JE2147: A Dipeptide Protease Inhibitor (PI) That Potently Inhibits Multi-PI-Resistant HIV1
John Erickson
Proceedings of The National Academy of Sciences, 1999
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An in silico pharmacological approach toward the discovery of potent inhibitors to combat drug resistance HIV‐1 protease variants
Ishwar Chandra D
Journal of Cellular Biochemistry, 2018
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Design and synthesis of sulfoximine based inhibitors for HIV1 protease
Abbas Raza
Bioorganic & Medicinal Chemistry Letters, 2008
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