The design of potent hydrazones and disulfides as cathepsin S inhibitors (original) (raw)

Discovery of selective and nonpeptidic cathepsin S inhibitors

Kazuhiko Nonomura

Bioorganic & Medicinal Chemistry Letters, 2008

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Potency and Selectivity of the Cathepsin L Propeptide as an Inhibitor of Cysteine Proteases †

John Mort

Biochemistry, 1996

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Evaluation of Dipeptide α-Keto-β-aldehydes as New Inhibitors of Cathepsin S

Dieter Brömme

Biochemical and Biophysical Research Communications, 2000

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In Search of Selective Inhibitors of Cysteine Protease, Cathepsin K

Anders Grubb

International Journal of Peptide Research and Therapeutics, 2005

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Development of cell-active non-peptidyl inhibitors of cysteine cathepsins

Pathegama G Ranjith

Bioorganic & Medicinal Chemistry, 2013

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Peptidyl vinyl sulphones: a new class of potent and selective cysteine protease inhibitors: S2P2 specificity of human cathepsin O2 in comparison with cathepsins S and L

James Palmer

Biochemical Journal, 1996

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Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype

isabel P leal

Bioorganic & Medicinal Chemistry Letters, 2008

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Diazinones as P2 replacements for pyrazole-based cathepsin S inhibitors

Siquan Sun, Scott Bembenek

Bioorganic & Medicinal Chemistry Letters, 2010

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6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors

Tommi Meulemans, Iain Martin, Leon van Berkom, Sylviane Boucharens, Jiaqiang Cai

Bioorganic & Medicinal Chemistry Letters, 2010

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Chalcones, semicarbazones and pyrazolines as inhibitors of cathepsins B, H and L

neera raghav

International journal of biological macromolecules, 2015

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Structural basis for reversible and irreversible inhibition of human cathepsin L by their respective dipeptidyl glyoxal and diazomethylketone inhibitors

Rajesh Shenoy

Journal of Structural Biology, 2011

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Design and evaluation of inhibitors for dipeptidyl peptidase I (Cathepsin C)

Dwain Thiele

Archives of Biochemistry and Biophysics, 2004

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Synthesis and evaluation of some semicarbazone- and thiosemicarbazone-based cathepsin B inhibitors

neera raghav

Medicinal Chemistry Research, 2014

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Identification of new peptide amides as selective cathepsin L inhibitors: The first step towards selective irreversible inhibitors?

Tamara Lah

Bioorganic & Medicinal Chemistry Letters, 2013

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3,4-Disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P3 elements for potency and selectivity

James Janc

Bioorganic & Medicinal Chemistry Letters, 2005

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Synthesis and SAR of succinamide peptidomimetic inhibitors of cathepsin S

Tove Tuntland

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Inhibition of a Cathepsin L-Like Cysteine Protease by a Chimeric Propeptide-Derived Inhibitor †

Maya Belghazi, Gilles Lalmanach

Biochemistry, 2005

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N-formylpyrazolines and N-benzoylpyrazolines as potential inhibitors cathepsin L

neera raghav

AIMS molecular science, 2016

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Discovery and SAR studies of a novel series of noncovalent cathepsin S inhibitors

Jianmei Wei

Bioorganic & Medicinal Chemistry Letters, 2005

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Large-Scale Asymmetric Synthesis of a Cathepsin S Inhibitor

joe johnson

Journal of Organic Chemistry, 2010

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Synthesis and inhibiting activities of 1-peptidyl-2-haloacetyl hydrazines toward cathepsin B and calpains

Roberto Scandurra, Raffaele Calabretta

European Journal of Medicinal Chemistry, 1993

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