p38 Inhibitors: piperidine- and 4-aminopiperidine-substituted naphthyridinones, quinolinones, and dihydroquinazolinones
Stephen O'Keefe
Bioorganic & Medicinal Chemistry Letters, 2003
View PDFchevron_right
Piperidine-based heterocyclic oxalyl amides as potent p38α MAP kinase inhibitors
Xuefei Tan
Bioorganic & Medicinal Chemistry Letters, 2010
View PDFchevron_right
Design and synthesis of piperazine-indole p38α MAP kinase inhibitors with improved pharmacokinetic profiles
vinh tran
Bioorganic & Medicinal Chemistry Letters, 2010
View PDFchevron_right
Design and synthesis of potent, orally bioavailable dihydroquinazolinone inhibitors of p38 MAP kinase
chris thompson
Bioorganic & Medicinal Chemistry Letters, 2003
View PDFchevron_right
Discovery of pyrrolo[2,1-f][1,2,4]triazine C6-ketones as potent, orally active p38α MAP kinase inhibitors
Gary Schieven
Bioorganic & Medicinal Chemistry Letters, 2011
View PDFchevron_right
KR-003048, a potent, orally active inhibitor of p38 mitogen-activated protein kinase
Antonio Garrido Montalban
European Journal of Pharmacology, 2010
View PDFchevron_right
SAR of 4-hydroxypiperidine and hydroxyalkyl substituted heterocycles as novel p38 map kinase inhibitors
Peter Hiestand
Bioorganic & Medicinal Chemistry Letters, 2000
View PDFchevron_right
SAR of benzoylpyridines and benzophenones as p38α MAP kinase inhibitors with oral activity
Peter Hiestand
Bioorganic & Medicinal Chemistry Letters, 2004
View PDFchevron_right
New Approaches to the Treatment of Inflammatory Disorders Small Molecule inhibitors of p38 MAP Kinase
Gerd Wagner, Christian Peifer
Current Topics in Medicinal Chemistry, 2006
View PDFchevron_right
Pharmacological profile of AW-814141, a novel, potent, selective and orally active inhibitor of p38 MAP kinase
Geeta Sharma
International Immunopharmacology, 2010
View PDFchevron_right
1,7-Naphthyridine 1-oxides as novel potent and selective inhibitors of p38 mitogen activated protein kinase
Laura Vidal
Journal of medicinal chemistry, 2011
View PDFchevron_right
Synthesis, anti-inflammatory, p38α MAP kinase inhibitory activities and molecular docking studies of quinoxaline derivatives containing triazole moiety
Sana Tariq
Bioorganic chemistry, 2017
View PDFchevron_right
6-Amino-2-(4-fluorophenyl)-4-methoxy-3- (4-pyridyl)-1H-pyrrolo[2,3-b]pyridine (RWJ 68354): A Potent and Selective p38 Kinase Inhibitor
Ignatius Turchi
Journal of Medicinal Chemistry, 1998
View PDFchevron_right
Structure−Activity Relationships of the p38α MAP Kinase Inhibitor 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea (BIRB 796)
Jeffrey Madwed
Journal of Medicinal Chemistry, 2003
View PDFchevron_right
SAR of 2,6-diamino-3,5-difluoropyridinyl substituted heterocycles as novel p38MAP kinase inhibitors
Peter Hiestand
Bioorganic & Medicinal Chemistry Letters, 2002
View PDFchevron_right
Structural basis for p38α MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity
Giovanna Scapin
Nature Structural Biology, 2003
View PDFchevron_right
Implications for selectivity of 3,4-diarylquinolinones as p38αMAP kinase inhibitors
Christian Peifer
Bioorganic & Medicinal Chemistry Letters, 2008
View PDFchevron_right
Novel p38 inhibitors with potent oral efficacy in several models of rheumatoid arthritis
Peter Hiestand
Bioorganic & Medicinal Chemistry Letters, 2004
View PDFchevron_right
Imidazolyl benzimidazoles and imidazo[4,5- b]pyridines as potent p38α MAP kinase inhibitors with excellent in vivo antiinflammatory properties
Bryan Dios
Bioorganic & Medicinal Chemistry Letters, 2008
View PDFchevron_right
Design and Synthesis of Potent, Selective, and Orally Bioavailable Tetrasubstituted Imidazole Inhibitors of p38 Mitogen-Activated Protein Kinase
Matthew Kostura
Journal of Medicinal Chemistry, 1999
View PDFchevron_right
Discovery of N-substituted pyridinones as potent and selective inhibitors of p38 kinase
lance christie
Bioorganic & medicinal …, 2009
View PDFchevron_right