Protective Efficacy of hGSTM1-1 against B[a]P and (+)- or ( )-B[a]P-7,8-Dihydrodiol Cytotoxicity, Mutagenicity, and Macromolecular Adducts in V79 Cells Coexpressing hCYP1A1
Sandra Kabler
Toxicological Sciences, 2007
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Cytotoxicity and mutagenicity of dibenzo[ a,l]pyrene and (±)-dibenzo[ a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione- S-transferase A1
Sarfaraz Ahmad
Mutation Research-fundamental and Molecular Mechanisms of Mutagenesis, 2007
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Regulation of Benzo[ a ]pyrene-Mediated DNA- and Glutathione-Adduct Formation by 2,3,7,8-Tetrachlorodibenzo- p -dioxin in Human Lung Cells
Stacy Gelhaus
Chemical Research in Toxicology, 2011
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A comparison of the genotoxicity of benzo[ a ]pyrene in four cell lines with differing metabolic capacity
Ume-Kulsoom Shah
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2016
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Repair of DNA damaged by mutagenic metabolites of benzo(a)pyrene in human cells
Oscar Guerra Hernandez
Chemico-Biological Interactions, 1978
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Stable Expression of Human Cytochrome P450 1B1 in V79 Chinese Hamster Cells and Metabolically Catalyzed DNA Adduct Formation of Dibenzo[ a , l ]pyrene
Volker Soballa, Albrecht Seidel
Chemical Research in Toxicology, 1998
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Aldo−Keto Reductase- and Cytochrome P450-Dependent Formation of Benzo[ a ]pyrene-Derived DNA Adducts in Human Bronchoalveolar Cells
Stacy Gelhaus
Chemical Research in Toxicology, 2007
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Comparison of the genotoxic activities of the K-region dihydrodiol of benzo[ a]pyrene with benzo[ a]pyrene in mammalian cells: morphological cell transformation; DNA damage; and stable covalent DNA adducts
Maria Pimentel
Mutation Research-genetic Toxicology and Environmental Mutagenesis, 2002
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Relationships between benzo(a)pyrene-DNA adduct levels and genotoxic effects in mammalian cells
George Hatch
Cancer research, 1987
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Mutagenesis by the (+)-anti-diol epoxide of benzo[a]pyrene: What controls mutagenic specificity?
Henry Rodriguez
Biochemistry, 1993
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Adducts, SCE's and Mutations following Benzo(a)pyrene Exposure: a Review of quantitative Data followed by some Considerations regarding Risk
Nik van Larebeke
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Identification and quantitation of benzo[a]pyrene-DNA adducts formed by rat liver microsomes in vitro
Ryszard Jankowiak
Chemical Research in Toxicology, 1992
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Benzo[a]pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytes
Eric Le FERREC
Biochemical Pharmacology, 2017
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Microsome-mediated bioactivation of dibenzo[a,l]pyrene and identification of DNA adducts by 32P-postlabeling
Jamal Arif
Carcinogenesis, 1997
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Mutagenicity of benzo[a]pyrene–deoxyadenosine adducts in a sequence context derived from the p53 gene
Homayoon Khalili
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2000
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Comparison of the morphological transforming activities of dibenzo[a,l]pyrene and benzo[a]pyrene in C3H10T1/2CL8 cells and characterization of the dibenzo[a,l]pyrene-DNA adducts
Dhimant Desai
Carcinogenesis, 1997
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Cytotoxicity and mutagenicity of 5-methylchrysene and its 1,2-dihydrodiol in V79MZ cells modified to express human CYP1A1 or CYP1B1, in the presence or absence of human GSTP1 coexpression
Sarfaraz Ahmad
Toxicology Letters, 2008
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Microsome-Mediated Benzo(A)Pyrene-Dna Binding and Inhibition by Cytosolic Fractions from Liver and Skin of Adult and Weanling Rats
Abdolamir Allameh
2001
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Identification and Quantitation of Dibenzo[a,l]pyrene-DNA Adducts Formed by Rat Liver Microsomes in Vitro: Preponderance of Depurinating Adducts
Ryszard Jankowiak
Biochemistry, 1995
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Comparison of cytochrome P450- and peroxidase-dependent metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in human cell lines: formation of stable DNA adducts and absence of a detectable increase in apurinic sites
Albrecht Seidel
Cancer research, 1999
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P01 Effect of Benzo(A)Pyrene Treatment on Hepatic Cytochrome P450 and Nadph:Cytochrome P450 Reductase (Por) Levels in Mice with Liver-Specific Deletion of the Por Gene
Dagmar Aimová
2000
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H2AX phosphorylation in A549 cells induced by the bulky and stable DNA adducts of benzo[a]pyrene and dibenzo[a,l]pyrene diol epoxides
Ian Cotgreave
Chemico-Biological Interactions, 2009
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DNA Adduct Formation in Precision-Cut Rat Liver and Lung Slices Exposed to Benzo[a]pyrene
James Olson
Toxicological Sciences, 2004
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Control of Glucose-6-Phosphate Dehydrogenase Deficiency on the Formation of Mutagenic and Carcinogenic Metabolites Derived from Benzo(a)pyrene
Francesco Feo
Toxicologic Pathology, 1987
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Alleviation of benzo[a]pyrene-diolepoxide-DNA damage in human lung carcinoma by glutathione S-transferase M2
Shun-fa Yang, Jiunn-liang Ko
DNA Repair, 2005
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Benzo[a]pyrene-Induced Toxicity: Paradoxical Protection in Cyp1a1(−/−) Knockout Mice Having Increased Hepatic BaP–DNA Adduct Levels
G. Talaska
Biochemical and Biophysical Research Communications, 2001
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<emph type="2">In Vitro</emph> and <emph type="2">In Vivo</emph> Studies on Oxygen Free Radical and DNA Adduct Formation in Rat Lung and Liver during Benzo[a]pyrene Metabolism
Jacob Briedé
Free Radical Research, 2004
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