Alleviation of benzo[a]pyrene-diolepoxide-DNA damage in human lung carcinoma by glutathione S-transferase M2 (original) (raw)

Expression of glutathione S-transferase M2 in stage I/II non-small cell lung cancer and alleviation of DNA damage exposure to benzo[a]pyrene

Chung-Ping Hsu

Toxicology Letters, 2010

View PDFchevron_right

Expression of human glutathione S-transferase P1 confers resistance to benzo(a)pyrene or benzo(a)pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1

Sandra Kabler

2007

View PDFchevron_right

Induction of glutathioneS-transferase π as a bioassay for the evaluation of potency of inhibitors of benzo(a)pyrene-induced cancer in a murine model

sanjay srivastava

International Journal of Cancer, 1997

View PDFchevron_right

Regulation of Benzo[ a ]pyrene-Mediated DNA- and Glutathione-Adduct Formation by 2,3,7,8-Tetrachlorodibenzo- p -dioxin in Human Lung Cells

Stacy Gelhaus

Chemical Research in Toxicology, 2011

View PDFchevron_right

Sensitivity to benzo(a)pyrene diol-epoxide associated with risk of breast cancer in young women and modulation by glutathione S-transferase polymorphisms: a case-control study

S Eva

Cancer research, 2001

View PDFchevron_right

Catalytic Activities of Human Alpha Class Glutathione Transferases toward Carcinogenic Dibenzo[ a , l ]pyrene Diol Epoxides †

Bengt Mannervik

Chemical Research in Toxicology, 2002

View PDFchevron_right

The role of DNA repair in benzene-induced carcinogenesis

Andrea Hartwig

Chemico-Biological Interactions, 2010

View PDFchevron_right

Binding of benzo(a)pyrene to rat lung glutathione S-transferases in vivo

shivendra srivastava

Febs Letters, 1985

View PDFchevron_right

Structural Basis for Catalytic Differences between α Class Human Glutathione Transferases hGSTA1-1 and hGSTA2-2 for Glutathione Conjugation of Environmental Carcinogen Benzo[a]pyrene-7,8-diol-9,10-epoxide

Dhimant Desai

Biochemistry, 2004

View PDFchevron_right

High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma

Nadine Martinet, Ingolf Cascorbi

2004

View PDFchevron_right

Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung

Costas Ioannides

Mutagenesis, 2008

View PDFchevron_right

p53 controls global nucleotide excision repair of low levels of structurally diverse benzo(g)chrysene-DNA adducts in human fibroblasts

Philip Hanawalt

Cancer research, 2002

View PDFchevron_right

Glutathione S-transferases of mouse lung. Selective binding of benzo [a] pyrene metabolites by the subunits which are preferentially induced by t-butylated …

Mukul Das

Biochemical …, 1987

View PDFchevron_right

Aldo−Keto Reductase- and Cytochrome P450-Dependent Formation of Benzo[ a ]pyrene-Derived DNA Adducts in Human Bronchoalveolar Cells

Stacy Gelhaus

Chemical Research in Toxicology, 2007

View PDFchevron_right

Impact of inherited polymorphisms in glutathione S-transferase M1, microsomal epoxide hydrolase, cytochrome P450 enzymes on DNA, and blood protein adducts of benzo(a)pyrene-diolepoxide

Marco Guanci

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998

View PDFchevron_right

Glycine N-Methyltransferase Tumor Susceptibility Gene in the Benzo(a)pyrene-Detoxification Pathway

Tsung-yun Liu

Cancer Research, 2004

View PDFchevron_right

Activity of Four Allelic Forms of Glutathione S-Transferase hGSTP1-1 for Diol Epoxides of Polycyclic Aromatic Hydrocarbons

sanjay srivastava

Biochemical and Biophysical Research Communications, 1997

View PDFchevron_right

Cytotoxicity and mutagenicity of dibenzo[ a,l]pyrene and (±)-dibenzo[ a,l]pyrene-11,12-dihydrodiol in V79MZ cells co-expressing either hCYP1A1 or hCYP1B1 together with human glutathione- S-transferase A1

Sarfaraz Ahmad

Mutation Research-fundamental and Molecular Mechanisms of Mutagenesis, 2007

View PDFchevron_right

Individual sensitivity to cytogenetic effects of benzo[alpha]pyrene in cultured human lymphocytes: influence of glutathione S-transferase M1 genotype

guven guven

Genetics and Molecular Biology, 2006

View PDFchevron_right

Repair of DNA damaged by mutagenic metabolites of benzo(a)pyrene in human cells

Oscar Guerra Hernandez

Chemico-Biological Interactions, 1978

View PDFchevron_right

Expression and polymorphism of glutathione S -transferase in human lungs: risk factors in smoking-related lung cancer

Ari Hirvonen

Carcinogenesis, 1995

View PDFchevron_right

Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons

Bengt Mannervik

Carcinogenesis, 1998

View PDFchevron_right

Microsome-Mediated Benzo(A)Pyrene-Dna Binding and Inhibition by Cytosolic Fractions from Liver and Skin of Adult and Weanling Rats

Abdolamir Allameh

2001

View PDFchevron_right

Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations

Bernd Kaina

Nucleic Acids Research, 2016

View PDFchevron_right

Benzo(a)pyrene metabolism by rat liver microsomes: effects of adding purified glutathione S-transferases A, B, and C

Ralf Morgenstern

Cancer research, 1982

View PDFchevron_right

P53-DEPENDENT Global Genomic Repair of BENZO[A]PYRENE-7,8-DIOL-9,10-EPOXIDE Adducts in Human Cells

Philip Hanawalt

Cancer research, 2000

View PDFchevron_right

Detoxication of carcinogenic fjord-region diol epoxides of polycyclic aromatic hydrocarbons by glutathione transferase P1-1 variants and glutathione

Bengt Mannervik

FEBS Letters, 1998

View PDFchevron_right

Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells

Stacy Gelhaus

Toxicology Letters, 2012

View PDFchevron_right

EXPOSURE OF MAMMALIAN CELLS TO DIOL EPOXIDES FROM BENZO[ A ]PYRENE AND DIBENZO[ A,L ]PYRENE AND EFFECTS ON Mdm2 AND P53

Albrecht Seidel, Ulla Stenius

Polycyclic Aromatic Compounds, 2004

View PDFchevron_right

Glutathione S-transferases and aromatic DNA adducts in smokers’ bronchoalveolar macrophages

Ari Hirvonen

Lung Cancer, 2003

View PDFchevron_right

The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice

Roger Godschalk

Archives of toxicology, 2015

View PDFchevron_right

Involvement of DNA polymerases in the repair of DNA damage by benzo[a]pyrene in cultured Chinese hamster cells

motoyasu ohsawa

Mutation Research/DNA Repair Reports, 1987

View PDFchevron_right

Benzo[a]pyrene-induced DNA damage associated with mutagenesis in primary human activated T lymphocytes

Eric Le FERREC

Biochemical Pharmacology, 2017

View PDFchevron_right