Inhibiting the inhibitors: Retro-inverso Smac peptides (original) (raw)

IAPS : More than just inhibitors of apoptosis proteins

Laurence Dubrez-daloz

Cell Cycle, 2008

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The membrane-associated inhibitor of apoptosis protein, BRUCE/Apollon, antagonizes both the precursor and mature forms of Smac and caspase-9

Alfred Goldberg

Journal of Biological Chemistry, 2004

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Inhibitors of Apoptotic Proteins: New Targets for Anticancer Therapy

M. I. Qadir

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Direct inhibition of caspase 3 is dispensable for the anti-apoptotic activity of XIAP

John Silke

The EMBO Journal, 2001

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Inhibitor of Apoptosis Proteins in Eukaryotic Evolution and Development: A Model of Thematic Conservation

Laura Bauler

Developmental Cell, 2008

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Targeting the BIR Domains of Inhibitor of Apoptosis (IAP) Proteins in Cancer Treatment

Eloise Mastrangelo

Computational and Structural Biotechnology Journal

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Distinct roles for the cellular inhibitors of apoptosis proteins 1 and 2

Tyson Graber

Cell Death and Disease, 2011

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Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs)

Jean Berthelet, Dubrez L

2013

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The Neuronal Apoptosis Inhibitory Protein Is a Direct Inhibitor of Caspases 3 and 7

Sophie Roy

2002

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Antagonists of IAP-family anti-apoptotic proteins - Probe 1

Marcos Lopez

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Mechanism of XIAP-Mediated Inhibition of Caspase-9

Stefan Riedl, S. Shivaprasad

Molecular Cell, 2003

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The zinc finger protein A20 interacts with a novel anti-apoptotic protein which is cleaved by specific caspases

Rudi Beyaert, Karen Heyninck

Oncogene, 1999

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XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs

Stefan Riedl

The EMBO Journal, 2005

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The BIR domain of IAP-like protein 2 is conformationally unstable: implications for caspase inhibition

Viviane Abreu Nunes

Biochemical …, 2005

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The anti-apoptotic activity of XIAP is retained upon mutation of both the caspase 3- and caspase 9-interacting sites

John Silke

Journal of Cell Biology, 2002

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To fight or die — inhibitor of apoptosis proteins at the crossroad of innate immunity and death

juanita lopez

Current Opinion in Cell Biology

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A single BIR domain of XIAP sufficient for inhibiting caspases

Ryosuke Takahashi

Journal of Biological …, 1998

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Peptides in apoptosis research

G. Malet, Ismael Mingarro

Journal of Peptide Science, 2002

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The inhibitors of apoptosis (IAPs) and their emerging role in cancer

Robert Korneluk, Stephen Baird

Oncogene, 1999

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An IAP-IAP Complex Inhibits Apoptosis

Temesgen Samuel

Journal of Biological Chemistry, 2004

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Targeting Inhibitors of Apoptosis Proteins (IAPs) For New Breast Cancer Therapeutics

liu liu

Journal of Mammary Gland Biology and Neoplasia, 2012

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ARTS binds to a distinct domain in XIAP-BIR3 and promotes apoptosis by a mechanism that is different from other IAP-antagonists

N. Edison

Apoptosis, 2011

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Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

brendan eckelman

Embo Reports, 2006

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The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9

Kirk Wright

Acta Crystallographica Section D-biological Crystallography, 2009

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