Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor-dependent migration and induces aggregation of nh(2)-terminal FAK in the nuclei of apoptotic glioblastoma cells
Joel Machado
Cancer research, 2001
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Differential Role of Proline-Rich Tyrosine Kinase 2 and Focal Adhesion Kinase in Determining Glioblastoma Migration and Proliferation1 1 National Institutes of Health Grants HL67938 (J.C.L.) and NS42262 (M.E.B.)
Michael Berens
Molecular Cancer Research, 2003
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Differential role of proline-rich tyrosine kinase 2 and focal adhesion kinase in determining glioblastoma migration and proliferation
Joseph Loftus
Molecular cancer research : MCR, 2003
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The Tyrosine Kinase Pyk2 Promotes Migration and Invasion of Glioma Cells
Michael Berens
Neoplasia, 2005
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Inhibition of focal adhesion kinase expression or activity disrupts epidermal growth factor-stimulated signaling promoting the migration of invasive human carcinoma cells
Joseph Loftus
Cancer research, 2001
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Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo
Dowdy Jackson
Molecular Cancer Therapeutics, 2007
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Pharmacologic blockade of FAK autophosphorylation decreases human glioblastoma tumor growth and synergizes with temozolomide
Brian Eliceiri
Molecular cancer therapeutics, 2013
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Protein Kinase A Activity In The Leading Edge of Migrating Cells Is Dependent On The Activity of Focal Adhesion Kinase
Alan Howe
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Pyk2/FAK Signaling Is Upregulated in Recurrent Glioblastoma Tumors in a C57BL/6/GL261 Glioma Implantation Model
Mikhail Inyushin
International Journal of Molecular Sciences
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Antitumor Activity and Pharmacology of a Selective Focal Adhesion Kinase Inhibitor, PF-562,271
Walter Roberts
Cancer Research, 2008
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Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and -861
Thomas Iskratsch
Cancer Research, 2019
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Extended survival of Pyk2 or FAK deficient orthotopic glioma xenografts
Michael Berens
Journal of Neuro-Oncology, 2008
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Focal adhesion kinase is involved in mechanosensing during fibroblast migration
Yu-li Wang
Proceedings of the National Academy of Sciences, 2001
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A Novel Interaction between Pyk2 and MAP4K4 Is Integrated with Glioma Cell Migration
Harshil Dhruv
Journal of signal transduction, 2013
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Platelet-derived growth factor-BB (PDGF-BB) regulation of migration and focal adhesion kinase phosphorylation in rabbit aortic vascular smooth muscle cells: roles of phosphatidylinositol 3-kinase and mitogen-activated protein kinases
Rosario Cospedal
Cardiovascular Research, 1999
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Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma
Immanuel Dhanasingh
Cancer biology & therapy, 2018
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Epidermal Growth Factor-Induced Tumor Cell Invasion and Metastasis Initiated by Dephosphorylation and Downregulation of Focal Adhesion Kinase
Guoqiang Jiang
Molecular and Cellular Biology, 2001
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Focal Adhesion Kinase: An Old Protein with New Roles
Atul Pandey
OnLine Journal of Biological Sciences
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Regulation of FAK Ser-722 phosphorylation and kinase activity by GSK3 and PP1 during cell spreading and migration
Stefania De Lucchini
Biochemical …, 2005
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The Pyk2 FERM domain as a target to inhibit glioma migration
Joseph Loftus
Molecular Cancer Therapeutics, 2009
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Regulation of focal adhesion dynamics and disassembly by phosphorylation of FAK at tyrosine 397
Monique Dontenwill
Journal of Cell Science, 2005
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Involvement of Focal Adhesion Kinase in Inhibition of Motility of Human Breast Cancer Cells by Sphingosine 1-Phosphate
Ana Olivera
Experimental Cell Research, 1999
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Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility
Jan Brábek
Frontiers in Bioscience, 2003
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L1 stimulation of human glioma cell motility correlates with FAK activation
magdy boulos
Journal of Neuro-oncology
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FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration
rodrigo jacamo
Journal of Cellular Physiology, 2007
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The role of focal-adhesion kinase in cancera new therapeutic opportunity
Egle Avizienyte
Nature Reviews …, 2005
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Focal adhesion kinase (FAK) phosphorylation is a key regulator of embryonal rhabdomyosarcoma (ERMS) cell viability and migration
Mana Alshehri
Journal of Cancer Research and Clinical Oncology, 2019
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G Protein-coupled Receptor Activation Rapidly Stimulates Focal Adhesion Kinase Phosphorylation at Ser-843: MEDIATION BY Ca2+, CALMODULIN, AND Ca2+/CALMODULIN-DEPENDENT KINASE II
Robert Fan
Journal of Biological Chemistry, 2005
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Inhibition of PKA Blocks Fibroblast Migration in Response to Growth Factors
Matthew Edin
Experimental Cell Research, 2001
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Synergistic Effect of Focal Adhesion Kinase Overexpression and Hepatocyte Growth Factor Stimulation on Cell Transformation
Po-Chao Chan
Journal of Biological Chemistry, 2002
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A Study of the Focal Adhesion Kinase Inhibitor GSK2256098 in Patients with Recurrent Glioblastoma with Evaluation of Tumor Penetration of [11C]GSK2256098
Kurt Auger
Neuro-oncology, 2018
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Focal Adhesion Kinase Expression in Human Neuroblastoma: Immunohistochemical and Real-time PCR Analyses
Wendy London
Clinical Cancer Research, 2008
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