Functional evolution of the vitamin D and pregnane X receptors (original) (raw)
The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species
Sean Ekins
BMC Biochemistry, 2011
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Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish
Mauro Rebelo
Comparative Biochemistry and Physiology C-toxicology & Pharmacology, 2005
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Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in Zebrafish (Danio rerio)
Anders Goksøyr, Roger Lille-langøy
Aquatic Toxicology, 2013
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Sequence Variations in pxr (nr1i2) From Zebrafish (Danio rerio) Strains Affect Nuclear Receptor Function
John Stegeman
Toxicological Sciences, 2018
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Cloning of a Functional Vitamin D Receptor from the Lamprey (Petromyzon marinus), an Ancient Vertebrate Lacking a Calcified Skeleton and Teeth
ralph bernstein
Endocrinology, 2003
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Role of Pregnane X Receptor and Aryl Hydrocarbon Receptor in Transcriptional Regulation of pxr, CYP2, and CYP3 Genes in Developing Zebrafish
Bruce Woodin
Toxicological sciences : an official journal of the Society of Toxicology, 2015
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Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR
Sean Ekins
Molecular and Cellular Endocrinology, 2011
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Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors)
Lee Hagey
Nuclear receptor, 2005
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Ligand specificity and evolution of liver X receptors
Lee Hagey
The Journal of Steroid Biochemistry and Molecular Biology, 2008
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The xenobiotic sensor PXR in a marine flatfish species (Solea senegalensis): Gene expression patterns and its regulation under different physiological conditions
Vânia Roberto
Marine environmental research, 2017
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Independent losses of a xenobiotic receptor across teleost evolution
John Stegeman
Scientific Reports, 2018
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Transcriptional modulation of brain and hepatic estrogen receptor and P450arom isotypes in juvenile Atlantic salmon (Salmo salar) after waterborne exposure to the xenoestrogen, 4-nonylphenol
Valentina Meucci
Aquatic Toxicology, 2006
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CRISPR-Cas9 mutated pregnane x receptor (pxr) retains pregnenolone-induced expression of cytochrome p450 family 3, subfamily A, polypeptide 65 (cyp3a65) in zebrafish (Danio rerio) larvae
Nadja Brun
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Molecular cloning, tissue expression and regulation of liver X Receptor (LXR) transcription factors of Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss)
Matteo Minghetti
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 2009
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Evolution of the Pregnane X Receptor: Adaptation to Cross-Species Differences in Biliary Bile Salts
Lee Hagey
Molecular Endocrinology, 2005
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Activation of Steroid and Xenobiotic Receptor (SXR, NR1I2) and Its Orthologs in Laboratory, Toxicologic, and Genome Model Species
Matthew Milnes
Environmental Health Perspectives, 2008
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New retinoid-X-receptor subtypes in Zebra fish (Danio rerio) differentially modulate transcription and do not bind 9-cis retinoic acid
Joseph Grippo
Molecular and Cellular Biology
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Liver X receptor agonist T0901317 induced liver perturbation in zebrafish: Histological, gene set enrichment and expression analyses
Sinnakaruppan Mathavan
Biochimica Et Biophysica Acta-general Subjects
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Transcriptional activity and biological effects of mammalian estrogen receptor ligands on three hepatic estrogen receptors in Mozambique tilapia
Taisen Iguchi
The Journal of Steroid Biochemistry and Molecular Biology, 2010
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Molecular evolution of angrogen receptors in fish
Yann Guiguen
Fish Physiology and Biochemistry, 2000
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Expression and Regulation of the Vitamin D Receptor in the Zebrafish, Danio rerio
Joseph Grande
Journal of Bone and Mineral Research, 2008
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The evolution of drug-activated nuclear receptors: one ancestral gene diverged into two xenosensor genes in mammals
Adrian Roth
Nuclear receptor, 2004
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Transcriptional profiling of cytochrome P450 genes in the liver of adult zebrafish, Danio rerio
Daisuke Kondoh
The Journal of Toxicological Sciences
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Molecular cloning, characterization, and evolutionary analysis of estrogen receptors from phylogenetically ancient fish
Satomi Kohno
Endocrinology, 2008
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Zebrafish Androgen Receptor: Isolation, Molecular, and Biochemical Characterization
Laszlo Orban
Biology of Reproduction, 2008
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DNA elements for constitutive androstane receptor- and pregnane X receptor-mediated regulation of bovine CYP3A28 gene
Jenni Küblbeck
PLOS ONE
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