original ) (raw )Evolution of the bile salt nuclear receptor FXR in vertebrates
Sean Ekins
The Journal of Lipid Research, 2008
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Evolution of the Pregnane X Receptor: Adaptation to Cross-Species Differences in Biliary Bile Salts
Lee Hagey
Molecular Endocrinology, 2005
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A Chemical, Genetic, and Structural Analysis of the Nuclear Bile Acid Receptor FXR
Mark Verdecia , A. Roecker , Marianne Bowman
Molecular Cell, 2003
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Functional evolution of the vitamin D and pregnane X receptors
Lee Hagey
BMC Evolutionary Biology, 2007
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Endogenous bile acids are ligands for the nuclear receptor FXR/BAR
Jasmine Chen
Molecular Cell, 1999
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Molecular Basis for Feedback Regulation of Bile Acid Synthesis by Nuclear Receptors
David Mangelsdorf
Molecular Cell, 2000
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Megatrends in bile acid receptor research
Luciano Adorini
Hepatology Communications
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Ligand specificity and evolution of liver X receptors
Lee Hagey
The Journal of Steroid Biochemistry and Molecular Biology, 2008
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Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR
Sean Ekins
Molecular and Cellular Endocrinology, 2011
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Identification of Pregnane X Receptor Binding Sites in the Regulatory Regions of Genes Involved in Bile Acid Homeostasis
Thomas Dunlop , Carsten Carlberg
Journal of Molecular Biology, 2005
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Bile acid receptors as targets for drug development
Peter Jansen
Nature Reviews Gastroenterology & Hepatology, 2013
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Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor
Bedri Durmishaj
Journal of Lipid Research, 2002
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Diversity of Bile Salts in Fish and Amphibians: Evolution of a Complex Biochemical Pathway
Peter R Møller
Physiological and Biochemical Zoology, 2010
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Pleiotropic functions of bile acids mediated by the farnesoid X receptor
Momir Mikov
Acta gastro-enterologica Belgica, 2012
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A Single Amino Acid Mutation in Zebrafish (Danio rerio) Liver Bile Acid-binding Protein Can Change the Stoichiometry of Ligand Binding
Dimitrios Fessas
Journal of Biological Chemistry, 2007
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Interactions between Bile Acids and Nuclear Receptors and Their Effects on Lipid Metabolism and Liver Diseases
Piero Portincasa
Journal of lipids, 2012
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The Amino Acid Residues Asparagine 354 and Isoleucine 372 of Human Farnesoid X Receptor Confer the Receptor with High Sensitivity to Chenodeoxycholate
Thomas Heard
Journal of Biological Chemistry, 2002
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Identification of a Bile Acid-responsive Element in the Human Ileal Bile Acid-binding Protein Gene INVOLVEMENT OF THE FARNESOID X RECEPTOR/9-cis-RETINOIC ACID RECEPTOR HETERODIMER
Philippe Besnard
Journal of Biological Chemistry, 1999
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Steroid Ring Hydroxylation Patterns Govern Cooperativity in Human Bile Acid Binding Protein
David Cistola
Biochemistry, 2003
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A Single Hydroxyl Group Governs Ligand Site Selectivity in Human Ileal Bile Acid Binding Protein
David Cistola
Journal of The American Chemical Society, 2004
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Two farnesoid X receptor alpha isoforms in Japanese medaka (Oryzias latipes) are differentially activated in vitro☆
Sean Ekins
Aquatic Toxicology, 2010
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Olfactory sensitivity to bile fluid and bile salts in the European eel (Anguilla anguilla), goldfish (Carassius auratus) and Mozambique tilapia (Oreochromis mossambicus) suggests a 'broad range' sensitivity not confined to those produced by conspecifics alone
Adelino V M Canario
The Journal of experimental biology, 2010
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Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump
Michael Muller
Hepatology, 2002
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Liver Receptor Homolog-1 Regulates Bile Acid Homeostasis but Is Not Essential for Feedback Regulation of Bile Acid Synthesis
Robert Hammer
Molecular Endocrinology, 2008
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Functional Characterization of the Semisynthetic Bile Acid Derivative INT-767, a Dual Farnesoid X Receptor and TGR5 Agonist
Luciano Adorini
Molecular Pharmacology, 2010
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Disrupted Bile Acid Homeostasis Reveals an Unexpected Interaction among Nuclear Hormone Receptors, Transporters, and Cytochrome P450
V. Lecureur
Journal of Biological Chemistry, 2001
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Activation of Steroid and Xenobiotic Receptor (SXR, NR1I2) and Its Orthologs in Laboratory, Toxicologic, and Genome Model Species
Matthew Milnes
Environmental Health Perspectives, 2008
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Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
Folkert Kuipers
Physiological Reviews, 2009
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AKR1B7 Is Induced by the Farnesoid X Receptor and Metabolizes Bile Acids
Samuel Schmidt
Journal of Biological Chemistry, 2010
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