original ) (raw )Syntheses and spectroscopic characterization of some phosphoramidates as reversible inhibitors of human acetylcholinesterase and determination of their potency
Mohammed Enamullah , Khosro Khajeh
Journal of Enzyme Inhibition and Medicinal Chemistry, 2006
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Structure-activity relations in reactivators of organophosphorus-inhibited acetylcholinesterase. 9. N-Heterocyclic acraldoximes methiodides
Francesca Arena
Journal of Medicinal Chemistry, 1975
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Structure-activity relations in reactivators of organophosphorus-inhibited acetylcholinesterase. 10. Hydroxyiminomethylarylethenylpyridine methiodides
Francesca Arena
J Med Chem, 1975
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Totally Selective Synthesis of Enantiopure (3 S ,5 S )- and (3 R ,5 R )-4-Amino-3,5-dihydroxypiperidines from Aminodiepoxides Derived from Serine
Santiago García-Granda
The Journal of Organic Chemistry, 2008
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Selectivity, acetylcholinesterase inhibition kinetics, and quantitative structure–activity relationships of a series of N-(2-oxido-1,3,2-benzodioxa-phosphol-2-yl) amino acid ethyl or diethyl esters
Hussein Ali
Pesticide Biochemistry and Physiology, 2005
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4-Aryl-4-oxo-N-phenyl-2-aminylbutyramides as acetyl- and butyrylcholinesterase inhibitors. Preparation, anticholinesterase activity, docking study, and 3D structure–activity relationship based on molecular interaction fields
Ivan Juranic
Bioorganic & Medicinal Chemistry, 2010
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A CoMFA Study of Enantiomeric Organophoshorus Inhibitors of Acetylcholinesterase
Philippe Bernard
Journal of Molecular Modeling, 2000
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Structure-activity relations in reactivators of organophosphorus-inhibited acetylcholinesterase. 7. 1-Aryl-2-hydroxyiminomethyl-3-methylimidazolium iodides
Francesca Arena
Journal of Medicinal Chemistry, 1974
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Quantitative structure-activity analysis of acetylcholinesterase inhibition by oxono and thiono analogs of organophosphorus compounds
Rolf Altenburger
Chemical Research in Toxicology, 1992
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A new key intermediate in the synthesis of 6-oxopiperidine-2-carboxylate derivatives
Hassan Allouchi
Acta Crystallographica Section E Structure Reports Online, 2004
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Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates
Zrinka Kovarik
Biochemical Journal, 2003
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Synthesis, characterization and inhibitory potency of two oxono and thiono analogues of phosphoramidate compounds on acetylcholinesterase
Hossein naderi-manesh
Journal of Enzyme Inhibition and Medicinal Chemistry, 2006
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Synthesis and Screening for Antiacetylcholinesterase Activity of (1Benzyl4-oxopiperidin-3-ylidene)methylindoles and -pyrroles Related to Donepezil
Aldo Andreani
Journal of Medicinal Chemistry, 2001
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Exploring the Active Center of Human Acetylcholinesterase with Stereomers of an Organophosphorus Inhibitor with Two Chiral Centers
Dov Barak
Biochemistry, 1999
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General approach to the synthesis of optically active 2-carboxy-4-[′3-(diethoxyphosphinyl)propyl]-5-alkylperazines (CCP analogues
Andrea Porcheddu
Tetrahedron-asymmetry, 1997
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The Absolute Configuration of the (þ)- and (� )-cis- and (þ)- and (� )-trans-1- Benzyl4-hydroxypiperidine-3-methanols: An Unusual Application of the 1 H-NMR-Mosher Method
Christian Clerc
2000
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Synthesis and Pharmacological Activity of 4-(4′-(Chlorophenyl)-4-hydroxypiperidine) Derivatives
Wolfgang Voelter
Chemical & …, 2005
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Design, Synthesis, and StructureActivity Relationship, Molecular Modeling, and NMR Studies of a Series of a Phenyl Alkyl Ketones as Highly Potent and Selective Phosphodiesterase4 Inhibitors
Xiaochuan Yang
Journal of Medicinal Chemistry, 2008
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Synthesis and conformational analysis of Substance P antagonist analogues based on a 1,7-naphthyridine scaffold
Frederik Rombouts
Tetrahedron, 2003
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Concise, stereodivergent and highly stereoselective synthesis of cis- and trans -2-substituted 3-hydroxypiperidines – development of a phosphite-driven cyclodehydration
Ari Koskinen
Beilstein Journal of Organic Chemistry, 2014
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Molecular docking and molecular dynamic studies of semi-synthetic piperidine alkaloids as acetylcholinesterase inhibitors
Carlos Fraga
Journal of the Brazilian Chemical Society, 2012
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Theoretical NMR and conformational analysis of solvated oximes for organophosphates-inhibited acetylcholinesterase reactivation
fahmi hilmi
Journal of Molecular Structure, 2017
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Synthesis, biological evaluation, QSAR study and molecular docking of novel N-(4-amino carbonylpiperazinyl) (thio)phosphoramide derivatives as cholinesterase inhibitors
Mahyar Bonsaii
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A novel and efficient one-pot synthesis of symmetrical diamide (bis-amidate) prodrugs of acyclic nucleoside phosphonates and evaluation of their biological activities
Zlatko Janeba
European Journal of Medicinal Chemistry, 2011
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An efficient and general method for the synthesis of 3-phosphorylated 4-aminoquinolines from β-phosphine oxide and phosphonate enamines
jesus garcia
Tetrahedron, 1997
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Structural determinations by analytical analysis of 7-phosphanorbornadiene derivatives and amino acid enantiomers
Stephen Fratpietro
2000
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Search for the Enaminal Derivative from the Dipalmitoyl Phosphatidyl Ethanolamine
Dipak Das
Annals of the New York Academy of Sciences, 1988
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Convenient synthesis and NMR spectral studies of variously substituted N-methylpiperidin-4-one-O-benzyloximes (Monatsh Chem (2009) 140:287–301)
P. Parthiban
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Biological activity of synthesized 5-{1-[(4-chlorophenyl)sulfonyl]piperidin-4-yl}-2-mercapto-1,3,4-oxadiazole derivatives demonstrated by in silico and BSA binding studies
Dr. Shahid Rasool
Brazilian Journal of Pharmaceutical Sciences
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The Synthesis and Absolute Configuration of Enantiomeric Pure (R)- and (S)-3-(piperidin-3-yl)-1H-Indole Derivatives
Ilona Materek
International Journal of Molecular Sciences
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Design, synthesis and biological activity of novel a,b-unsaturated carbonyl compounds as acetylcholinesterase inhibitors
Paul T P Wong
2010
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Synthesis of phosphorylated chrysin derivatives and estimation of efficiency and selectivity of their inhibitory activity towards carboxylesterase
Alexander Bogachenkov
Russian Journal of General Chemistry, 2016
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Synthesis of α-Heterocyclic α-Aminophosphonates, 1 Part II: Morpholine, Piperidine, Pyrrolidine, Tetrahydrofurylmethylamine, N -Benzyl- N -Methylamine, and Aniline Derivatives
Abdelrhani Elachqar
Phosphorus, Sulfur, and Silicon and the Related Elements, 2007
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Synthesis, Characterization, Acetylcholinesterase Inhibition, Molecular Modeling and Antioxidant Activities of Some Novel Schiff Bases Derived from 1-(2-Ketoiminoethyl)piperazines
Hapipah Mohd Ali
2011
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N-[11C]methylpiperidine esters as acetylcholinesterase substrates: an in vivo structure–reactivity study
thinh nguyen
Nuclear Medicine and Biology, 1998
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