ExoT of Cytotoxic Pseudomonas aeruginosa Prevents Uptake by Corneal Epithelial Cells (original) (raw)

Contribution of ExsA-Regulated Factors to Corneal Infection by Cytotoxic and Invasive Pseudomonas aeruginosa in a Murine Scarification Model

Suzanne Fleiszig

Investigative Ophthalmology & Visual Science, 2003

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ExoS and ExoT ADP ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival

Mausita Karmakar

The Journal of …, 2012

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Traversal of Multilayered Corneal Epithelia by Cytotoxic Pseudomonas aeruginosa Requires the Phospholipase Domain of ExoU

Suzanne Fleiszig

Investigative Ophthalmology & Visual Science, 2012

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Role of Pseudomonas aeruginosa ExsA in Penetration through Corneal Epithelium in a Novel In Vivo Model

Suzanne Fleiszig

Investigative Ophthalmology & Visual Science, 2003

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Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity

Suzanne Fleiszig

Experimental Eye Research, 2007

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The ADP Ribosyltransferase Domain of Pseudomonas aeruginosa ExoT Contributes to Its Biological Activities

Sasha Shafikhani

Infection and Immunity, 2004

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Cytotoxicity and corneal epithelial cell invasion by isolates of Pseudomonas aeruginosa

Suzanne Fleiszig

Infection and Immunity

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Ecto-ADP-ribosyltransferase activity of Pseudomonas aeruginosa exoenzyme S

David Knight

Infection and immunity, 1997

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The ADP-Ribosylation Domain of Pseudomonas aeruginosa ExoS Is Required for Membrane Bleb Niche Formation and Bacterial Survival within Epithelial Cells

Suzanne Fleiszig

Infection and Immunity, 2010

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Pseudomonas aeruginosa invasion and cytotoxicity are independent events, both of which involve protein tyrosine kinase activity

Suzanne Fleiszig

Infection and immunity, 1998

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Relationship between cytotoxicity and corneal epithelial cell invasion by clinical isolates of Pseudomonas aeruginosa

Suzanne Fleiszig

Infection and immunity

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Pseudomonas aeruginosa mediated apoptosis requires the ADP-ribosylating activity of exoS

Un-Hwan Ha

Microbiology (Reading, England), 2000

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The Importance of the Pseudomonas aeruginosa Type Three Secretion System in Epithelial Traversal Depends Upon Conditions of Host Susceptibility

Suzanne Fleiszig

Infection and immunity, 2015

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Pseudomonas aeruginosa invades corneal epithelial cells during experimental infection

Suzanne Fleiszig

Infection and immunity, 1994

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Pseudomonas aeruginosa survival and multiplication within corneal epithelial cells in vitro

Suzanne Fleiszig

Infection and Immunity

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Pseudomonas aeruginosa internalization by corneal epithelial cells involves MEK and ERK signal transduction proteins

Suzanne Fleiszig

FEMS Microbiology Letters, 2002

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Mutation of lasA and lasB reduces Pseudomonas aeruginosa invasion of epithelial cells

Suzanne Fleiszig

Microbiology, 2003

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Mechanistic Studies of the Roles of the Transcriptional Activator ExsA and Anti-activator Protein ExsD in the Regulation of the Type Three Secretion System in Pseudomonas aeruginosa

Manisha Shrestha

2018

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Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence

Suzanne Fleiszig

Microbial Pathogenesis, 2011

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Pseudomonas aeruginosa Strains with Lipopolysaccharide Defects Exhibit Reduced Intracellular Viability after Invasion of Corneal Epithelial Cells

Suzanne Fleiszig

Experimental Eye Research, 2002

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FlhA, a Component of the Flagellum Assembly Apparatus of Pseudomonas aeruginosa, Plays a Role in Internalization by Corneal Epithelial Cells

Suzanne Fleiszig

Infection and Immunity, 2001

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Backbone Interactions Between Transcriptional Activator ExsA and Anti-Activator ExsD Facilitate Regulation of the Type III Secretion System in Pseudomonas aeruginosa

Manisha Shrestha

Scientific Reports, 2020

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Pseudomonas aeruginosa Utilizes the Type III Secreted Toxin ExoS to Avoid Acidified Compartments within Epithelial Cells

Suzanne Fleiszig

PLoS ONE, 2013

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Self‐trimerization of ExsD limits inhibition of the Pseudomonas aeruginosa transcriptional activator ExsA in vitro

Florian Schubot

The FEBS Journal, 2013

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The Importance of the Pseudomonas aeruginosa Type III Secretion System in Epithelium Traversal Depends upon Conditions of Host Susceptibility

Suzanne Fleiszig

Infection and Immunity, 2015

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Mechanism of Transcriptional Activation by Pseudomonas aeruginosa ExsA

Keith Brady

Journal of Bacteriology, 2009

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The N-terminal Domain of Pseudomonas aeruginosa Exoenzyme S Is a GTPase-activating Protein for Rho GTPases

K. Aktories

Journal of Biological Chemistry, 1999

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Zaidi TS, Fleiszig SM, Preston MJ, Goldberg JB, Pier GB. Lipopolysaccharide outer core is a ligand for corneal cell binding and ingestion of Pseudomonas aeruginosa

Suzanne Fleiszig

Investigative Ophthalmology &amp Visual Science

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Lipopolysaccharide outer core is a ligand for corneal cell binding and ingestion of Pseudomonas aeruginosa

Suzanne Fleiszig

Investigative ophthalmology & visual science, 1996

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Actin cytoskeleton disruption by ExoY and its effects on Pseudomonas aeruginosa invasion

Suzanne Fleiszig

FEMS Microbiology Letters, 2005

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Type III Secretion-Dependent Modulation of Innate Immunity as One of Multiple Factors Regulated by Pseudomonas aeruginosa RetS

Suzanne Fleiszig

Infection and Immunity, 2006

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Role of Defensins in Corneal Epithelial Barrier Function against Pseudomonas aeruginosa Traversal

Suzanne Fleiszig

Infection and …, 2011

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Structural Analysis of the Regulatory Domain of ExsA, a Key Transcriptional Regulator of the Type Three Secretion System in Pseudomonas aeruginosa

Florian Schubot

PloS one, 2015

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Pseudomonas aeruginosa ExsE, a secreted regulator of type III secretion genes in

Arne Rietsch

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Characterization of ExsA and of ExsA-dependent promoters required for expression of the Pseudomonas aeruginosa type III secretion system

Keith Brady

Molecular Microbiology, 2008

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