Pseudomonas aeruginosa internalization by corneal epithelial cells involves MEK and ERK signal transduction proteins (original) (raw)

Tyrosine kinases required for Pseudomonas aeruginosainvasion

Alexa Riehle

Respiratory Research

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Pseudomonas aeruginosa invasion and cytotoxicity are independent events, both of which involve protein tyrosine kinase activity

Suzanne Fleiszig

Infection and immunity, 1998

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Mutation of csk, encoding the C-terminal Src kinase, reduces Pseudomonas aeruginosa internalization by mammalian cells and enhances bacterial cytotoxicity

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Microbial Pathogenesis, 2002

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Polyphosphate Kinase 1 and the Ocular Virulence of Pseudomonas aeruginosa

Jeffery Hobden

Investigative Ophthalmology & Visual Science, 2005

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ExoT of Cytotoxic Pseudomonas aeruginosa Prevents Uptake by Corneal Epithelial Cells

David Chen

Infection and Immunity, 2000

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Pseudomonas aeruginosa invades corneal epithelial cells during experimental infection

Suzanne Fleiszig

Infection and immunity, 1994

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Cytotoxicity and corneal epithelial cell invasion by isolates of Pseudomonas aeruginosa

Suzanne Fleiszig

Infection and Immunity

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Pseudomonas aeruginosa survival and multiplication within corneal epithelial cells in vitro

Suzanne Fleiszig

Infection and Immunity

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Relationship between cytotoxicity and corneal epithelial cell invasion by clinical isolates of Pseudomonas aeruginosa

Suzanne Fleiszig

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Role of Pseudomonas aeruginosa ExsA in Penetration through Corneal Epithelium in a Novel In Vivo Model

Suzanne Fleiszig

Investigative Ophthalmology & Visual Science, 2003

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The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa

Manjeet Bains

Microbiology, 2009

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Traversal of Multilayered Corneal Epithelia by Cytotoxic Pseudomonas aeruginosa Requires the Phospholipase Domain of ExoU

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Investigative Ophthalmology & Visual Science, 2012

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The Importance of the Pseudomonas aeruginosa Type Three Secretion System in Epithelial Traversal Depends Upon Conditions of Host Susceptibility

Suzanne Fleiszig

Infection and immunity, 2015

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Contribution of ExsA-Regulated Factors to Corneal Infection by Cytotoxic and Invasive Pseudomonas aeruginosa in a Murine Scarification Model

Suzanne Fleiszig

Investigative Ophthalmology & Visual Science, 2003

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Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity

Suzanne Fleiszig

Experimental Eye Research, 2007

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FlhA, a Component of the Flagellum Assembly Apparatus of Pseudomonas aeruginosa, Plays a Role in Internalization by Corneal Epithelial Cells

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Infection and Immunity, 2001

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Pseudomonas aeruginosa ExoT Induces Atypical Anoikis Apoptosis in Target Host Cells by Transforming Crk Adaptor Protein into a Cytotoxin

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Pseudomonas aeruginosa can diversify after host cell invasion to establish multiple intracellular niches

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bioRxiv (Cold Spring Harbor Laboratory), 2022

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Pseudomonas aeruginosa host-pathogen interactions in human corneal infection models

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Targeting mechanisms of Pseudomonas aeruginosa pathogenesis

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Medecine et Maladies Infectieuses, 2006

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Contribution of an arsenal of virulence factors to pathogenesis of Pseudomonas aeruginosa infections

Tanya Strateva

Annals of Microbiology, 2011

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ExoS and ExoT ADP ribosyltransferase activities mediate Pseudomonas aeruginosa keratitis by promoting neutrophil apoptosis and bacterial survival

Mausita Karmakar

The Journal of …, 2012

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Pseudomonas aeruginosa Strains with Lipopolysaccharide Defects Exhibit Reduced Intracellular Viability after Invasion of Corneal Epithelial Cells

Suzanne Fleiszig

Experimental Eye Research, 2002

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Pseudomonas aeruginosa Acquires Biofilm-Like Properties within Airway Epithelial Cells

Pradeep Singh

Infection and Immunity, 2005

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Factors impacting corneal epithelial barrier function against Pseudomonas aeruginosa traversal

Irania Alarcon

Investigative ophthalmology & visual science, 2011

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The Role of Twitching Motility in Pseudomonas aeruginosa Exit from and Translocation of Corneal Epithelial Cells

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Investigative Ophthalmology & Visual Science, 2009

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The Sensor Kinase KinB Regulates Virulence in Acute Pseudomonas aeruginosa Infection

Anne Clatworthy

Journal of Bacteriology, 2011

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The Importance of the Pseudomonas aeruginosa Type III Secretion System in Epithelium Traversal Depends upon Conditions of Host Susceptibility

Suzanne Fleiszig

Infection and Immunity, 2015

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Predatory Bacteria can ReducePseudomonas aeruginosaInduced Corneal Perforation and Proliferation in a Rabbit Keratitis Model

Eric Romanowski

bioRxiv (Cold Spring Harbor Laboratory), 2023

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The role of type 4 pilus, flagella and type III secretion system in the interactions between Pseudomonas aeruginosa bacteria and corneal fibroblasts in human microbial keratitis

Parwez Hossain

Investigative Ophthalmology & Visual Science, 2016

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A proof-of-concept model for the identification of the key events in the infection process with specific reference to Pseudomonas aeruginosa in corneal infections

Ilias Soumpasis

Infection ecology & epidemiology, 2015

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Role of the Corneal Epithelial Basement Membrane in Ocular Defense against Pseudomonas aeruginosa

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Modification of Pseudomonas aeruginosa Interactions with Corneal Epithelial Cells by Human Tear Fluid

Suzanne Fleiszig

Infection and Immunity, 2003

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The junctional integrity of epithelial cells is modulated by Pseudomonas aeruginosa quorum sensing molecule through phosphorylation-dependent mechanisms

Elena Vikström, Karl-eric Magnusson

Experimental Cell Research, 2009

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Host Response and Bacterial Virulence Factor Expression in Pseudomonas aeruginosa and Streptococcus pneumoniae Corneal Ulcers

Rajapandian Siva Ganesa Karthikeyan

PLoS ONE, 2013

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