Ontogeny of CD40 expression by activated peripheral blood lymphocytes in humans (original) (raw)

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Ontogeny of CD40 expression by activated peripheral blood lymphocytes in humans

1996

Daniel Graf

Alberto G. Ugazio

Luigi Notarangelo

Richard Kroczek

Massimo Marconi

Annarosa Soresina

Abstract

The CD40 ligand (CD40L) is a molecule expressed by activated T cells which plays a critical role in the regulation of B-cell responses, including differentiation into Ig-producing cells. Using the specific monoclonal antibody TRAP1 we have evaluated the ontogeny of CD40L ...

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