Chromosomal biomarkers of genomic instability relevant to cancer (original) (raw)

Whole chromosome gain does not in itself confer cancer-like chromosomal instability

B. Baldetorp

Proceedings of the National Academy of Sciences, 2013

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The role of chromosomal alterations in human cancer development

marco alessandro pierotti

Journal of Cellular Biochemistry, 2007

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Gene Dosage Imbalance Contributes to Chromosomal Instability-Induced Tumorigenesis

Najate Benhra

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Aneuploidy, the Primary Cause of the Multilateral Genomic Instability of Neoplastic and Preneoplastic Cells

Alice Fabarius, Peter Duesberg

Iubmb Life, 2004

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Genetic Instability of Cancer Cells is Proportional to their Degree of Aneuploidy

David Rasnick, Peter Duesberg

Proceedings of The National Academy of Sciences, 1998

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Cancer Genes and Chromosome Instability

Aleksei A Stepanenko

Oncogene and Cancer - From Bench to Clinic, 2013

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Instability of chromosome structure in cancer cells increases exponentially with degrees of aneuploidy

Peter Duesberg

Cancer Genetics and Cytogenetics, 2003

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The Role of Chromosomal Instability in Cancer and Therapeutic Responses

Milena Rondón Lagos

Cancers

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Genomic Instability and Cancer

D. Kuppuswamy

Current Molecular Medicine, 2003

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The role of chromosomal instability in tumor initiation

Anirvan Sengupta

Proceedings of the National Academy of Sciences, 2002

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The chromosomal basis of cancer

Peter Duesberg

Cellular oncology : the official journal of the International Society for Cellular Oncology, 2005

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Evidence that both genetic instability and selection contribute to the accumulation of chromosome alterations in cancer

Joanne Staines

Carcinogenesis, 2004

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Chromosomal instability is associated with higher expression of genes implicated in epithelial-mesenchymal transition, cancer invasiveness, and metastasis and with lower expression of genes involved in cell cycle checkpoints, DNA repair, and chromatin maintenance

Ilan Kirsch

Neoplasia (New York, N.Y.), 2008

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Role of genomic instability in human carcinogenesis

Jung Moon

Experimental Biology and Medicine, 2019

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Genomic instability — the engine of tumorigenesis?

Oliver Sieber

Nature Reviews Cancer, 2003

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Genomic instability in context of the chromosomal theory

Peter Duesberg

Cellular oncology : the official journal of the International Society for Cellular Oncology, 2008

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Gene amplification: an example of accelerated evolution in tumorigenic cells

Inder Gadi

Proceedings of the National Academy of Sciences of the United States of America, 1985

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Can chromosomal instability initiate tumorigenesis?

Martin Nowak

Seminars in Cancer Biology, 2005

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Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances

David Mack

Genes, Chromosomes and Cancer, 2012

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Aneuploidy versus gene mutation as cause of cancer

Peter Duesberg

CURRENT SCIENCE …, 2001

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Cancer-causing karyotypes: chromosomal equilibria between destabilizing aneuploidy and stabilizing selection for oncogenic function

Peter Duesberg

Cancer Genetics and Cytogenetics, 2009

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Chromosomal Chaos and Cancer

Peter Duesberg

Scientific American, 2007

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Induction of aneuploidy by increasing chromosomal instability during dedifferentiation of hepatocellular carcinoma

michael gebel

Pathology - Research and Practice, 2004

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Generation of trisomies in cancer cells by multipolar mitosis and incomplete cytokinesis

Ingrid Øra, Nils Mandahl

Proceedings of the National Academy of Sciences, 2010

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A signature of chromosomal instability inferred from gene expression profiles predicts clinical outcome in multiple human cancers

Scott Carter

Nature Genetics, 2006

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A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells

Hee-Sheung Lee, V. Larionov

BMC cancer, 2013

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Increased chromosome instability but not cancer predisposition in haploinsufficientBub3 mice

Belinda Griffiths

Genes, Chromosomes and Cancer, 2005

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Mutagenesis, Malignancy and Genome Instability

Jeremy Bartos

2000

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Systematic over-expression screens for chromosome instability identify conserved dosage chromosome instability genes in yeast and human tumors

Cornelius Boerkoel

2016

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Strong association between cancer and genomic instability

Christian Streffer

Radiation and Environmental Biophysics, 2010

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Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations

Mary Cutler

Proceedings of the National Academy of Sciences, 2007

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Role of heterochromatin variation in the instability of a marker chromosome during tumor progression

P. Comoglio

Cancer Genetics and Cytogenetics, 1985

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Replication stress links structural and numerical cancer chromosomal instability

Nadeem Shaikh

Nature, 2013

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Emerging links among Chromosome Instability (CIN), cancer, and aging

Hiroshi Y . Yamada

Molecular carcinogenesis, 2017

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