The role of chromosomal alterations in human cancer development (original) (raw)

Making of fusion genes in cancer: An in-silico study of mechanism of chromosomal translocations

Afzal Ansari

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SUPPLEMENTARY DATA MATERIAL: Characterization of Chromosomal Translocation Breakpoint Sequences in Solid Tumours: “An In Silico Analysis”

Afzal Ansari

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Chromosomal Translocation Engineering to Recapitulate Primary Events of Human Cancer

Naty Lopez Rodriguez

Cold Spring Harbor Symposia on Quantitative Biology, 2005

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Signatures of Selection in Fusion Transcripts Resulting From Chromosomal Translocations in Human Cancer

Francisco Novo

PLoS ONE, 2009

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Proteomic Identification of Oncogenic Chromosomal Translocation Partners Encoding Chimeric Anaplastic Lymphoma Kinase Fusion Proteins

Cheryl Coffin

2006

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Genomic Hallmarks of Genes Involved in Chromosomal Translocations in Hematological Cancer

Francisco Novo

PLoS Computational Biology, 2012

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Gene Fusion events in Human Cancers

W.Hashini Jayathunga

PENSEE, 2021

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Fusion genes in solid tumors

Pierre Åman

Seminars in Cancer Biology, 1999

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Chromosome translocation based on illegitimate recombination in human tumors

Jessica zucman-rossi

Proceedings of the National Academy of Sciences, 1998

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Chromosomal biomarkers of genomic instability relevant to cancer

Michael Fenech

Drug Discovery Today, 2002

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Chromosome translocations in cancer: computational evidence for the random generation of double-strand breaks

J. Vizmanos

Trends in Genetics, 2006

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Genes that contribute to cancer fusion genes are large and evolutionarily conserved

Alfred Mbah

Cancer Genetics and Cytogenetics, 2009

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Identification of novel cancer fusion genes using chromosome breakpoint screening

Kate Hua

Oncology reports, 2017

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Lymphoma- and leukemia-associated chromosomal translocations in healthy individuals

Siegfried Janz

Genes, Chromosomes and Cancer, 2003

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TFG, a target of chromosome translocations in lymphoma and soft tissue tumors, fuses to GPR128 in healthy individuals

Andreas Fiebig

Haematologica, 2009

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Dynamic chromosomal rearrangements in Hodgkin's lymphoma are due to ongoing three-dimensional nuclear remodeling and breakage-bridge-fusion cycles

H. Knecht

Haematologica, 2010

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Epigenetic Changes Associated with Chromosomal Translocation in Leukemia

S. Nicovani

Myeloid Leukemia - Basic Mechanisms of Leukemogenesis, 2011

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Evidence of recurrent gene fusions in common epithelial tumors

Chandan Kumar-sinha

Trends in Molecular Medicine, 2006

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Complex oncogenic translocations with gene amplification are initiated by specific DNA breaks in lymphocytes

Yong Woo

Cancer research, 2009

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Finding fusion genes resulting from chromosome rearrangement by analyzing the expressed sequence databases

Ilan Kirsch

Proceedings of the …, 2004

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Cryptic ETV6-PDGFRB fusion in a highly complex rearrangement of chromosomes 1, 5, and 12 due to a chromothripsis-like event in a myelodysplastic syndrome/myeloproliferative neoplasm

Vu Duong

Leukemia & lymphoma, 2018

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Deciphering the Code of the Cancer Genome: Mechanisms of Chromosome Rearrangement

Nicholas Willis

Trends in Cancer, 2015

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Chromosome rearrangement associated inactivation of tumour suppressor genes in prostate cancer

Bryan Lee Hui Young

American Journal of Cancer Research, 2011

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Fusion oncogenes in tumor development

AMAN IMPORT

Seminars in Cancer Biology, 2005

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Comparison of constitutional and tumor-associated 11;22 translocations: nonidentical breakpoints on chromosomes 11 and 22

Jacques Ghysdael

Proceedings of the National Academy of Sciences of the United States of America, 1986

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Chromosomal Rearrangements and Altered Nuclear Organization: Recent Mechanistic Models in Cancer

Sabrina Tosi

Cancers, 2021

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Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray

Jochen Harbott

Proceedings of the National Academy of Sciences, 2008

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Mll fusions generated by Cre-loxP-mediated de novo translocations can induce lineage reassignment in tumorigenesis

Nicole Chan

The EMBO Journal, 2005

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Possible involvement of unstable sites on chromosomes 7 and 14 in human cancer

Jacques Scheres

Cancer Genetics and Cytogenetics, 1986

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Identification of Tumor Suppressor Genes via Cell Fusion and Chromosomal Transfer

Yee Ko

Tumor Suppressor Genes, 2012

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