T Cell Tolerance and the Thymusa (original) (raw)

Stage-dependent reactivity of thymocytes to self-peptide–MHC complexes

Jianzhu Chen

Proceedings of the National Academy of Sciences, 2007

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Positive selection of self-MHC-reactive T cells by individual peptide–MHC class II complexes

Marcela Gomez

Proceedings of the …, 2002

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Differential processing of self-antigens by subsets of thymic stromal cells

Hervé Luche

Current Opinion in Immunology, 2012

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Peripheral Expression of Self-MHC-II Influences the Reactivity and Self-Tolerance of Mature CD4+ T Cells

A. Bhandoola

Immunity, 2002

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Cutting edge: negative selection of immature thymocytes by a few peptide-MHC complexes: differential sensitivity of immature and mature T cells

Osami Kanagawa

Journal of immunology (Baltimore, Md. : 1950), 1999

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Role of thymic cortex-specific self-peptides in positive selection of T cells

Takeshi Nitta

Seminars in Immunology, 2010

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Major Histocompatibility Complex Class II-Positive Cortical Epithelium Mediates the Selection of Cd4+25+ Immunoregulatory T Cells

Andrew Caton

Journal of Experimental Medicine, 2001

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Antibodies Directed Against the MHC-I Molecule H-2Dd Complexed with an Antigenic Peptide: Similarities to a T Cell Receptor with the Same Specificity

David H Margulies

The Journal of Immunology, 2000

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MHC class II peptide flanking residues of exogenous antigens influence recognition by autoreactive T cells

Stephanie Conant

Autoimmunity Reviews, 2003

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Divergent Changes in the Sensitivity of Maturing T Cells to Structurally Related Ligands Underlies Formation of a Useful T Cell Repertoire

Bruno Lucas

Immunity, 1999

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Precursors of Functional MHC Class I- or Class II-Restricted CD8αα+ T Cells Are Positively Selected in the Thymus by Agonist Self-Peptides

Mitchell Kronenberg

Immunity, 2002

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Specificity to a T Cell Receptor with the Same Similarities with an Antigenic Peptide: Complexed d MHC-I Molecule H-2D Antibodies Directed Against the

Jay Berzofsky

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T cell receptor engagement by peptide- MHC ligands induces a conformational change in the CD3 complex of thymocytes

Diana Gil

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Self-Tolerance and the Composition of T Cell Repertoire

Anwar Murtaza

Immunologic Research, 2000

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Specific Recognition of Thymic Self-Peptides Induces the Positive Selection of Cytotoxic T Lymphocytes

Joseph Opferman

Immunity, 1997

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MHC-peptide ligand interactions establish a functional threshold for antigen-specific T cell recognition

Sandra Reichstetter

1999

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Decreased Binding of Peptides-MHC Class I (pMHC) Multimeric Complexes to CD8 Affects Their Binding Avidity for the TCR But Does Not Significantly Impact on pMHC/TCR Dissociation Rate

charles hesdorffer

The Journal of Immunology, 2003

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CD4+ T-cell responses to self-peptide–MHC

Jianzhu Chen

Trends in Immunology, 2003

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An autonomous CDR3δ is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by γδ T cells

Erin Adams

Nature Immunology, 2008

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Autoreactive T cells can be protected from tolerance induction through competition by flanking determinants for access to class II MHC

Emanual Maverakis

Proceedings of the National Academy of Sciences, 2003

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Structure of an Autoimmune T Cell Receptor Complexed with Class II Peptide-MHCInsights into MHC Bias and Antigen Specificity

Erin Adams

Immunity, 2005

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CD8 T Cells, Like CD4 T Cells, Are Triggered by Multivalent Engagement of TCRs by MHC-Peptide Ligands but Not by Monovalent Engagement1

Lawrence Stern

2000

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CD8 T cells, like CD4 T cells, are triggered by multivalent engagement of TCRs by MHC-peptide ligands but not by monovalent engagement

Jennifer Stone

The Journal of Immunology, 2006

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Regulatory T cells and co‐evolution of allele‐specific MHC recognition by the TCR

ROBYN LINDLEY

Scandinavian Journal of Immunology, 2019

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Immunology: How Do T Cells Recognize Antigen?

Anton Merwe

Current Biology, 2005

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pMHC/TCR Dissociation Rate Not Significantly Impact on Does Binding Avidity for the TCR But Complexes to CD8 Affects Their Class I (pMHC) Multimeric Decreased Binding of Peptides-MHC

Valérie Dutoit

2000

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Not by Monovalent Engagement but of TCRs by MHC-Peptide Ligands Engagement Triggered by Multivalent CD8 T Cells, Like CD4 T Cells, Are

Jennifer Stone

2010

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Low-affinity peptides and T-cell selection

Rainer Böckmann

Trends in Immunology, 2009

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The TCR's sensitivity to self peptide–MHC dictates the ability of naive CD8+ T cells to respond to foreign antigens

Sara Hamilton

Nature Immunology, 2014

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How the T Cell Repertoire Becomes Peptide and MHC Specific

Eric Huseby

Cell, 2005

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A Role for CD8 in the Developmental Tuning of Antigen Recognition and CD3 Conformational Change1

Adam Schrum

2000

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Affinity of thymic self-peptides for the TCR determines the selection of CD8+ T lymphocytes in the thymus

Joseph Opferman

International Immunology, 2000

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A constant affinity threshold for T cell tolerance

Mark Daniels

Journal of Experimental Medicine, 2007

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