Mitochondrial DNA: more than an evolutionary bystander (original) (raw)

Natural Selection on Human Mitochondrial DNA

Chuan-Chao Wang

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Mitochondrial whims: metabolic rate, longevity and the rate of molecular evolution

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Comparative Genomics and the Evolution of Human Mitochondrial DNA: Assessing the Effects of Selection

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Progress' renders detrimental an ancient mitochondrial DNA genetic variant

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Human Molecular Genetics, 2011

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Evolution of the mitochondrial genetic system: an overview

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Victoria Metcalf

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An Ecologist’s Guide to Mitochondrial DNA Mutations and Senescence

Geoffrey Hill

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Mitochondrial DNA and two perspectives on evolutionary genetics

Steven Carr

… Journal of the …, 1985

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Variation in mitochondrial genotype has substantial lifespan effects which may be modulated by nuclear background

David Clancy

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Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA

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The role of selection in the evolution of human mitochondrial genomes

Toomas Kivisild

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Linking the mitochondrial genotype to the organismal phenotype

Richard Melvin

Molecular Ecology, 2010

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De Benedictis, G. et al. Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans. FASEB J. 13, 1532-1536

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Transmission of Functional, Wild-Type Mitochondria and the Fittest mtDNA to the Next Generation: Bottleneck Phenomenon, Balbiani Body, and Mitophagy

Szczepan Bilinski

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Large Variation in the Ratio of Mitochondrial to Nuclear Mutation Rate across Animals: Implications for Genetic Diversity and the Use of Mitochondrial DNA as a Molecular Marker

Stefano Donega

Molecular Biology and Evolution, 2017

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What cost mitochondria? The maintenance of functional mitochondrial DNA within and across generations

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Ageing and mammalian mitochondrial genetics

Yau-huei Wei

Trends in Genetics, 1998

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Mitochondrial mutational spectrum provides an universal marker of cellular and organismal longevity

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2019

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Naturally Occurring Mitochondrial Dna Haplotypes Exhibit Metabolic Differences: Insight Into Functional Properties of Mitochondria

J William O Ballard

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Experimental evidence that thermal selection shapes mitochondrial genome evolution

Zdenek Lajbner

Scientific Reports, 2018

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Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans

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Mitochondrial genome function and maternal inheritance

Wilson de Paula

2016

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Natural selection of mitochondria during somatic lifetime promotes healthy aging

Albert Gjedde

2013

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Effects of Purifying and Adaptive Selection on Regional Variation in Human mtDNA

D. Mishmar

Science, 2004

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The co-occurrence of mtDNA mutations on different oxidative phosphorylation subunits, not detected by haplogroup analysis, affects human longevity and is population specific

Laura Lomartire

Aging Cell, 2013

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