Silencing of heat shock factor 1: A potential therapeutic strategy for pancreatic cancer (original) (raw)

Targeting heat shock response pathways to treat pancreatic cancer

Palma Rocchi

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Hyperthermia-associated carboplatin resistance: Differential role of p53, HSF1 and Hsp70 in hepatoma cells

Avtar Singh Meena

Cancer Science, 2010

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Implication of Heat Shock Factors in Tumorigenesis: Therapeutical Potential

Aurelie de thonel

Cancers, 2011

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Targeting Heat Shock Protein 90 in Pancreatic Cancer Impairs Insulin-like Growth Factor-I Receptor Signaling, Disrupts an Interleukin-6/Signal-Transducer and Activator of Transcription 3/Hypoxia-Inducible Factor-1α Autocrine Loop, and Reduces Orthotopic Tumor Growth

Felix Popp

Clinical Cancer Research, 2007

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The Clinical Significance of Phosphorylated Heat Shock Protein 27 (HSPB1) in Pancreatic Cancer

Seiji Adachi

International Journal of Molecular Sciences, 2016

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Differential Expression of Heat Shock Proteins in Pancreatic Carcinoma

Helmut Friess

1994

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Stimulated upregulation of HO‑1 is associated with inadequate response of gastric and ovarian cancer cell lines to hyperthermia and cisplatin treatment

Zilvinas Dambrauskas

Oncology Letters

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Impact of Heat Shock Proteins in Hepatocellular Carcinoma

Mihir Parmar

International Journal of Cell Science & Molecular Biology

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Targeting heat shock proteins in cancer

Gaetan Jego

Cancer Letters, 2013

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The significance of phosphorylated heat shock protein 27 on the prognosis of pancreatic cancer

Seiji Adachi

Oncotarget, 2016

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Overexpression of heat shock protein 27 (HSP27) increases gemcitabine sensitivity in pancreatic cancer cells through S-phase arrest and apoptosis

Eric Kampmann

Journal of cellular and molecular medicine, 2015

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Mouse Pancreatic Cancer Cells from KRASG12D/P53−/− Transgenic Mice Overexpress Heat Shock Protein 70 (HSP70), and Its Inhibition by Triptolide Decreases Cell Viability

Yumi Yokoyama

Pancreas, 2008

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Inhibiting heat shock protein 90 and the ubiquitin-proteasome pathway impairs metabolic homeostasis and leads to cell death in human pancreatic cancer cells

Ganji Nagaraju

Cancer, 2017

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Heat Shock Proteins: Their Role in Tumor Development and Their Therapeutic Applications Against Cancer

Tilaye S . Mengistu

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Heat Shock Protein 70 Increases Tumorigenicity and Inhibits Apoptosis in Pancreatic Adenocarcinoma

Rajinder Dawra

Cancer Research, 2007

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Heat Shock Protein 27 Protects L929 Cells from Cisplatin-Induced Apoptosis by Enhancing Akt Activation and Abating Suppression of Thioredoxin Reductase Activity

Xun Shen

Clinical Cancer Research, 2007

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Interplay between heat shock proteins, inflammation and cancer: a potential cancer therapeutic target

Simphiwe Mbatha

American journal of cancer research, 2019

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Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice

Volker Schmitz

Hepatology, 2009

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Panobinostat reduces hypoxia-induced cisplatin resistance of non-small cell lung carcinoma cells via HIF-1α destabilization

Franz Quehenberger

Molecular cancer, 2015

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Heat shock protein 27 as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma

Denise Buchner

Journal of Cellular and Molecular Medicine, 2012

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Heat shock protein 27 was up-regulated in cisplatin resistant human ovarian tumor cell line and associated with the cisplatin resistance

Aikou Okamoto

Cancer Letters, 2001

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Heat shock transcription factor Hsf1 is involved in tumor progression via regulation of hypoxia-inducible factor 1 and RNA-binding protein HuR

Michael Sherman

Molecular and cellular biology, 2012

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Targeting heat shock factor 1 with a triazole nucleoside analog to elicit potent anticancer activity on drug-resistant pancreatic cancer

Palma Rocchi

Cancer Letters, 2012

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Narrow line between benefit and harm: Additivity of hyperthermia to cisplatin cytotoxicity in different gastrointestinal cancer cells

Zilvinas Dambrauskas

World journal of gastroenterology, 2018

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Synergistic Antipancreatic Tumor Effect by Simultaneously Targeting Hypoxic Cancer Cells With HSP90 Inhibitor and Glycolysis Inhibitor

Wendy Frankel

Clinical Cancer Research, 2008

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Heat Shock Proteins:Roles in Thermotolerance and as Molecular Targets for Cancer Therapy

Takaaki Matsumoto

Thermal Medicine(Japanese Journal of Hyperthermic Oncology), 1998

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Membrane-Associated Heat Shock Proteins in Oncology: From Basic Research to New Theranostic Targets

László Vigh

Cells, 2020

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Heat shock proteins as targets in oncology

Alejandra Ortiz

Clinical & Translational Oncology, 2010

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Radiosensitization of Normoxic and Hypoxic H1339 Lung Tumor Cells by Heat Shock Protein 90 Inhibition Is Independent of Hypoxia Inducible Factor1

daniela schilling

PLOS One, 2012

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Triptolide Induces Pancreatic Cancer Cell Death via Inhibition of Heat Shock Protein 70

Rajinder Dawra

2000

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Expression levels of heat shock protein 20 decrease in parallel with tumor progression in patients with hepatocellular carcinoma

Takashi Kumada

Oncology Reports, 2007

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Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia

Natalia Vydra

BMC Genomics, 2013

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Attenuating effects of heat shock against TGF-β1-induced apoptosis in cultured rat hepatocytes

David Andrés

Free Radical Biology and Medicine, 2002

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Cytotoxicity and cell signalling induced by continuous mild hyperthermia in freshly isolated mouse hepatocytes

Jose Alberto Duarte

Toxicology, 2006

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