Identification of human liver cytochrome P450 isoforms mediating omeprazole metabolism
Tommy Andersson
British Journal of Clinical Pharmacology, 1993
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Identification of Residues 99, 220, and 221 of Human Cytochrome P450 2C19 as Key Determinants of Omeprazole Hydroxylase Activity
lee pedersen
Journal of Biological Chemistry, 1996
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Omeprazole Coinduces Multiple Xenobiotic‐metabolizing Enzymes in the Rata
Khosrow Kashfi
Annals of the New York Academy of Sciences, 1995
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The hydroxylation of omeprazole correlates with S -mephenytoin and proguanil metabolism
Selim Kortunay
European Journal of Clinical Pharmacology, 1997
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Effect of clopidogrel on the hydroxylation and sulfoxidation of omeprazole: A single dose study in healthy human volunteers
Dr Abad Khan
EXCLI journal, 2017
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Simultaneous determination of omeprazole, hydroxyomeprazole and omeprazole sulphone in human plasma by isocratic HPLC-DAD: application to the phenotyping of CYP2C19 and CYP3A4 in brazilian volunteers
Andre Arigony
Journal of the Brazilian Chemical Society, 2007
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Comparative Effects of Rabeprazole and Omeprazole on the Inducibility of Cytochrome P450-1A and Cytochrome P450-3A Isoenzymes in Human Hepatocytes, and Effects on Cyclosporin Metabolism in Human Liver Microsomes
Patrick Maurel
Clinical Drug Investigation, 2000
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Increased omeprazole metabolism in carriers of the CYP2C19*17 allele; a pharmacokinetic study in healthy volunteers
Staffan Rosenborg
British Journal of Clinical Pharmacology, 2008
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Induction of Cytochrome P-450 1A1 by Omeprazole in Human HepG2 Cells Is Protein Tyrosine Kinase-Dependent and Is Not Inhibited by α-Naphthoflavone
Anwar hossain
Archives of Biochemistry and Biophysics, 1998
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CYP2C19- and CYP3A4-Dependent Omeprazole Metabolism in West Mexicans
Héctor González
The Journal of Clinical Pharmacology, 2003
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Evidence of human metabolites of omeprazole and its structure elucidation by using HPLC-MS
Mohammad Hailat
Journal of Molecular Structure, 2021
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Omeprazole: Effects on Oxidative Drug Metabolism in the Rat
Peter Dosen
Clinical and Experimental Pharmacology and Physiology, 1986
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Omeprazole and aryl hydrocarbon hydroxylases: Should we be worried?
D. Kim Turgeon
Hepatology, 1991
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Phenotype of CYP2C19 and CYP3A4 by determination of omeprazole and its two main metabolites in plasma using liquid chromatography with liquid–liquid extraction
Carlos Hoyo
Journal of Chromatography B, 2002
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Ethoxy-, pentoxy-and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450
Richard Mayer
Biochemical …, 1985
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Identification of the Cytochrome P450 Enzymes Involved in theN-Oxidation of Voriconazole
ruth hyland
Drug Metabolism and Disposition, 2003
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Omeprazole limited sampling strategies to predict area under the concentration–time curve ratios: implications for cytochrome P450 2C19 and 3A phenotyping
Staffan Rosenborg
European Journal of Clinical Pharmacology, 2012
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Sensitive quantification of omeprazole and its metabolites in human plasma by liquid chromatography–mass spectrometry
Ute Hofmann
Journal of Chromatography B, 2006
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Improved procedure for quantitation of omeprazole and metabolites using reversed-phase high-performance liquid chromatography
Michael Amantea
Journal of Chromatography B: Biomedical Sciences and Applications, 1988
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Kinetics of omeprazole degradation in the presence of 2‐mercaptoethanol
Ali Al-matar
International Journal of …, 2008
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Inhibition of Human Cytochrome P450 Enzymes by 1,2-Dithiole-3-thione, Oltipraz and Its Derivatives, and Sulforaphane
André Guillouzo
Chemical Research in Toxicology, 2000
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Pharmacokinetics and pharmacodynamics of esomeprazole, the S-isomer of omeprazole
Tommy Andersson
Alimentary Pharmacology and Therapeutics, 2001
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Omeprazole preferentially inhibits the metabolism of (+)-(S)-citalopram in healthy volunteers
Adriana Rocha
British Journal of Clinical Pharmacology, 2010
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Sensitive sulphur-specific detection of omeprazole metabolites in rat urine by high-performance liquid chromatography/inductively coupled plasma mass spectrometry
Lars Weidolf
Rapid Communications in Mass Spectrometry, 2004
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Identification of the human cytochromes P450 catalysing the rate‐limiting pathways of gliclazide elimination
Benjamin Lewis
British journal of …, 2007
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Hydroxylation index of omeprazole in relation to CYP2C19 polymorphism and sex in a healthy Iranian population
reza tahvilian
DARU Journal of Pharmaceutical Sciences, 2014
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Cytochrome P 450 enzymes induced roles in pharamacokinetic and drug interaction
Pálma Porrogi
2016
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Identification of the cytochrome P450 enzymes involved in theN-demethylation of sildenafil
ruth hyland
British Journal of Clinical Pharmacology, 2001
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Metabolism of a 5HT6 Antagonist, 2-Methyl-1-(Phenylsulfonyl)-4-(Piperazin-1-yl)-1H-Benzo[d]imidazole (SAM-760): Impact of Sulfonamide Metabolism on Diminution of a Ketoconazole-Mediated Clinical Drug-Drug Interaction
Peter Lockwood
Drug Metabolism and Disposition, 2018
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Effects of Omeprazole and Genetic Polymorphism of CYP2C19 on the Clopidogrel Active Metabolite
Nassim Djebli, Xavier Boulenc
Drug Metabolism and Disposition, 2012
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Contribution of human cytochrome P -450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine
Patrick Maurel
British Journal of Pharmacology, 2003
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Effects of the Proton Pump Inhibitors Omeprazole and Pantoprazole on the Cytochrome P450-Mediated Metabolism of Venlafaxine
Christoph Hiemke
Clinical Pharmacokinetics, 2017
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Quantitative Prediction of the in Vivo Inhibition of Diazepam Metabolism by Omeprazole Using Rat Liver Microsomes and Hepatocytes
brian houston
Drug Metabolism and Disposition, 2004
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