Constitutive expression of the pre-TCR enables development of mature T cells (original) (raw)
Early TCR Expression and Aberrant T Cell Development in Mice with Endogenous Prerearranged T Cell Receptor Genes
Rudolf Jaenisch
The Journal of Immunology, 2007
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The timing of TCR expression critically influences T cell development and selection
M. Sandau
Journal of Experimental Medicine, 2005
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The timing of TCR alpha expression critically influences T cell development and selection
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The Journal of experimental medicine, 2005
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Molecular mechanisms that control mouse and human TCR-αβ and TCR-γδ T cell development
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TCRβ enhancer activation occurs in some but not all cells with T cell lineage developmental potential
Aaron Martin
Cellular Immunology, 2003
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TCR gene rearrangements and expression of the pre-T cell receptor complex during human T-cell differentiation
Arjen Bakker
Blood, 1999
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T Cell Development in TCR Enhancer-Deleted Mice: Implications for T Cell Lineage Commitment and Differentiation
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The Journal of Immunology, 2000
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Regulation of pre-T cell receptor (pTα-TCRβ) gene expression during human thymic development
Maria Toribio
Journal of Experimental Medicine
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Regulation of pre-T cell receptor (pT alpha-TCR beta) gene expression during human thymic development
Maria Toribio
Journal of Experimental Medicine, 1996
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T cells in mice expressing a transgenic human TCRbeta chain get positively selected but cannot be activated in the periphery by signaling through TCR
annie george
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Development of T cells expressing an altered TCR complex
Thomas Ramos
European Journal of Immunology, 2003
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TCRA Gene Rearrangement in Immature Thymocytes in Absence of CD3, Pre-TCR, and TCR Signaling
Pierre Ferrier
The Journal of Immunology, 2001
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Is TCR β expression an essential event in early thymocyte development?
Donald Palmer
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TCRγ Silencing during αβ T Cell Development Depends upon Pre-TCR-Induced Proliferation
Luc Otten
The Journal of Immunology, 2006
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Identification of a Late Stage of Small Noncycling pT - Pre-T Cells as Immediate Precursors of T Cell Receptor / + Thymocytes
Maria Toribio
Journal of Experimental Medicine, 1998
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Regulation of naive T cell differentiation by varying the potency of TCR signal transduction
David Leitenberg
Seminars in Immunology, 1999
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Early Molecular Events Induced by T Cell Receptor (TCR) Signaling in Immature CD4 + CD8 + Thymocytes: Increased Synthesis of TCR-c~ Protein Is an Early Response to TCR Signaling That Compensates for TCR-c~ Instability, Improves TCR Assembly, and Parallels Other Indicators of Positive Selection
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2000
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Regulation of T-cell progenitor survival and cell-cycle entry by the pre-T-cell receptor
Tomas Vilimas, Malay Mandal
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In vivo fate mapping identifies pre-TCR expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis
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Journal of Experimental Medicine, 2013
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Selective Expression of the 21-Kilodalton Tyrosine-Phosphorylated Form of TCR ζ Promotes the Emergence of T Cells with Autoreactive Potential
Edward Wakeland
The Journal of Immunology, 2005
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In vivo fate mapping identifies pre-TCRα expression as an intra- and extrathymic, but not prethymic, marker of T lymphopoiesis
Hervé LUCHE
Journal of Experimental Medicine, 2013
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Agonist Ligands Expressed by Thymic Epithelium Enhance Positive Selection of Regulatory T Lymphocytes from Precursors with a Normally Diverse TCR Repertoire
Joost Van Meerwijk, Paola Romagnoli
The Journal of Immunology, 2006
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Developmental and Molecular Characterization of Emerging β- and γδ-Selected Pre-T Cells in the Adult Mouse Thymus
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Premature TCRab Expression and Signaling in Early Thymocytes Impair Thymocyte Expansion and Partially Block Their Development
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The Journal of Immunology, 2001
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Threshold of pre-T-cell-receptor surface expression is associated with αβ T-cell lineage commitment
Alexander Scheffold
Current Biology, 1999
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TCR repertoire selection in the thymus and peripheral T cell
Alexander Fleming
2007
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Premature TCR Expression and Signaling in Early Thymocytes Impair Thymocyte Expansion and Partially Block Their Development
Ljiljana Vasovic
The Journal of Immunology, 2001
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Posttranslational regulation of TCR Vα allelic exclusion during T cell differentiation
Nicholas Gascoigne
The Journal of Immunology, 1998
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Characterization of TCR Gene Rearrangements During Adult Murine T Cell Development
Michelle Tourigny
The Journal of Immunology, 1999
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A Transgenic TCR Directs the Development of IL-4+ and PLZF+ Innate CD4 T Cells
Joy Das
The Journal of Immunology, 2013
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Agonist ligands expressed by thymic epithelium enhance positive selection of regulatory T lymphocytes from precursors with a normally diverse TCR-repertoire 1
Joost Van Meerwijk
2006
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Selective Expression of the 21-Kilodalton Tyrosine-Phosphorylated Form of TCR Promotes the Emergence of T Cells with Autoreactive Potential
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The Journal of Immunology, 2005
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NF-κB Activation by the Pre-T Cell Receptor Serves as a Selective Survival Signal in T Lymphocyte Development
Adrian Hayday
Immunity, 2000
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Early molecular events induced by TCR signaling in immature CD4+ CD8+ thymocytes
Kelly Kearse
1995
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Positive Selection by the Pre-TCR Yields Mature CD8+ T Cells
Nicolai van Oers
The Journal of Immunology, 2002
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