Detection of point mutations with a modified ligase chain reaction (Gap-LCR) (original) (raw)

Selective Amplification of Rare Mutations Using Locked Nucleic Acid Oligonucleotides that Competitively Inhibit Primer Binding to Wild-Type DNA

Reid Oldenburg

Journal of Investigative Dermatology, 2008

View PDFchevron_right

Ligation of a primer at a mutation: a method to detect low level mutations in DNA

Brendan Price

Mutagenesis, 2002

View PDFchevron_right

A Ligase-Mediated Gene Detection Technique

Robert Kaiser

Science, 1988

View PDFchevron_right

Mutation Detection by Denaturing DNA Chromatography Using Fluorescently Labeled Polymerase Chain Reaction Products

Karl Hecker

Analytical Biochemistry, 1999

View PDFchevron_right

Mutant DNA Polymerase for Improved Detection of Single-Nucleotide Variations in Microarrayed Primer Extension

Ramon Kranaster

ChemBioChem, 2008

View PDFchevron_right

Detection of single-base DNA mutations by enzyme-amplified electronic transduction

Itamar Willner

Nature biotechnology, 2001

View PDFchevron_right

Amplified DNA analysis and single-base mismatch detection using DNA-bioelectronic systems

Amir Lichtenstein

View PDFchevron_right

Improved heteroduplex detection of single-base substitutions in PCR-amplified DNA

Armand Peeters

Genome Research, 1994

View PDFchevron_right

Ultrasensitive single-nucleotide polymorphism detection using target-recycled ligation, strand displacement and enzymatic amplification

Dejian Zhou

Nanoscale, 2013

View PDFchevron_right

Genetic analysis of amplified DNA with immobilized sequence-specific oligonucleotide probes

Corey Levenson

Proceedings of the National Academy of Sciences of the United States of America, 1989

View PDFchevron_right

Advances in ligase chain reaction and ligation-based amplifications for genotyping assays: Detection and applications

Ola Adel

Mutation Research/Reviews in Mutation Research, 2017

View PDFchevron_right

Detection and location of single-base mutations in large DNA fragments by immunomicroscopy

Gerard Tromp

Genomics, 1989

View PDFchevron_right

Mutation Detection by Ligation to Complete n-mer DNA Arrays

Kevin Gunderson

Genome Research, 1998

View PDFchevron_right

LigAmp for sensitive detection of single-nucleotide differences

Dana Jones

Nature Methods, 2004

View PDFchevron_right

SuperSelective primer pairs for sensitive detection of rare somatic mutations

Fred Kramer

Scientific Reports

View PDFchevron_right

Single-Molecule Detection of Specific Nucleic Acid Sequences in Unamplified Genomic DNA

alonso castro

Analytical Chemistry, 1997

View PDFchevron_right

Sensitive detection of DNA polymorphisms by the serial invasive signal amplification reaction

Bruce Neri

Proceedings of the National Academy of Sciences, 2000

View PDFchevron_right

Strand displacement amplification--an isothermal, in vitro DNA amplification technique

michael little

Nucleic Acids Research, 1992

View PDFchevron_right

Detection of human genomic mutations by chemical single-reaction DNA sequencing

Giovanna Costanzo

Technical Tips Online, 1997

View PDFchevron_right

Single base pair mutation analysis by PNA directed PCR clamping

Henrik Orum

Nucleic Acids Research, 1993

View PDFchevron_right

Kinetic Hairpin Oligonucleotide Blockers for Selective Amplification of Rare Mutations

Yanwei Jia

Scientific Reports, 2014

View PDFchevron_right

Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification

Gerard Pals

Nucleic acids …, 2002

View PDFchevron_right

A protocol for the in vitro selection of specific oligonucleotide probes for high-resolution DNA typing

Maja Krajinovic, Ivan Brukner, Damian Labuda

Nature Protocols, 2007

View PDFchevron_right

Exploiting the Enzymatic Recognition of an Unnatural Base Pair to Develop a Universal Genetic Analysis System

Eric Roesch

2003

View PDFchevron_right

Ultraspecific and Amplification-Free Quantification of Mutant DNA by Single-Molecule Kinetic Fingerprinting

Nils Walter

Journal of the American Chemical Society, 2018

View PDFchevron_right

Ligase-based detection of mononucleotide repeat sequences

Timothy McCaffrey

Nucleic Acids Research, 1999

View PDFchevron_right

Evaluation of MutS as a tool for direct measurement of point mutations in genomic DNA

Barbara Parsons

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1997

View PDFchevron_right

Rolling circle amplification of DNA immobilized on solid surfaces and its application to multiplex mutation detection

Cl Smith

Genetic Analysis - Biomolecular Engineering, 1999

View PDFchevron_right

Rapid determination of single base mismatch mutations in DNA hybrids by direct electric field control

Michael Heller

Proceedings of the National Academy of Sciences, 1997

View PDFchevron_right

A sensitive scanning technology for low frequency nuclear point mutations in human genomic DNA

William Thilly

Nucleic Acids Research, 2000

View PDFchevron_right

In situ genotyping individual DNA molecules by target-primed rolling-circle amplification of padlock probes

Mats Nilsson

Nature Methods, 2004

View PDFchevron_right

Ligation of high-melting-temperature 'clamp' sequence extends the scanning range of rare point-mutational analysis by constant denaturant capillary electrophoresis (CDCE) to most of the human genome

William Thilly

Nucleic Acids Research, 2003

View PDFchevron_right

Development of a colorimetric test system for detection of point mutations via ligation of a tandem of short oligonucleotides on methacrylate beads

David Tabatadze

Molecular Biology, 2000

View PDFchevron_right